Directions to 221 Longwood Ave, Boston

221 Longwood General Instruction

Note: This building is on the corner of Avenue Louis Pasteur and Longwood Avenue. It is the building of the former Lying-In Hospital. Handicapped parking is available on-site

Please arrive at 221 Longwood Ave and VALET park your vehicle. Your parking will be validated for your time at the clinic.

ACC Front Desk: 617-732-6860

Directions inside the building:

A Study Staff member will greet you at the Clinical Center of Investigation clinic (3rd floor.)

1.  Enter through the front doors of 221 Longwood Avenue
2. In the lobby, you will see a security desk to your right
3. Turn left and walk down the hallway, past the small cafe.
4. At the end of the hallway, you will see an elevator on your left
5. Take these elevators to the 3rd floor and check in at the reception desk.

221 Longwood Driving Directions

From the West: Head east on the Mass Pike to exit 22 (Prudential/Copley). Stay left on the exit ramp following the signs for the Prudential Center. You will exit onto Huntington Avenue (Route 9 West). Follow past the Museum of Fine Arts and Mass. College of Art and go right onto Longwood Avenue. 221 Longwood Avenue is on your right. Valet parking is available in front of the building. 

From the South: Head north on Route 3. Take the Massachusetts Ave./Roxbury exit. At end of ramp, cross Massachusetts Avenue onto Melnea Cass Boulevard. At the 8th traffic light, take left onto Tremont Street. Take first right onto Ruggles Street. Turn left onto Huntington Avenue at intersection with Ruggles Street. Turn right onto Longwood Avenue. 221 Longwood is on the right-hand side of the street. 

From Routes 93 North or South: Take the Storrow Drive exit. At the top of the exit ramp, bear right at the first traffic light. Continue straight for 1/2 mile (the road will become Brookline Avenue). Turn left onto Longwood Avenue. The main entrance for 221 Longwood Avenue is on the left, just after the Longwood Avenue and Avenue Louis Pasteur intersection. Valet parking is available in front of the building. 

221 Longwood by Transit

The nearest MBTA bus routes and subway lines to the hospital are:

• “E” Line: Heath Street Stop: Longwood Medical Area
• “D” Line: Riverside, Stop: Longwood
• Bus No. 66 to Dudley Station, Stop: Brigham Circle
• Bus No. 65 to Kenmore Station, Stop: Corner of Brookline and Longwood Avenues
• Bus No. 60 to Kenmore Station, Stop” Corner of Brookline and Longwood Avenues
• Bus No. 47 to Broadway Station, Stop: Corner of Louis Pasteur and Longwood Avenues
• Bus No. 39 to Back Bay Station, Stop: Corner of Longwood and Huntington Avenues
• Bus No. 8 to Kenmore Station, Stop: Corner of Louis Pasteur and Longwood Avenues
• Bus No. CT2 to Ruggles Station, Stop: Corner of Longwood and Huntington Avenues
• Bus No. CT3 to Andrew Station, Stop: Corner of Louis Pasteur and Longwood Avenues