About the research

Phase 2 Dose Response (DR):

This study will identify dietary intake biomarkers. In other words, we will study the body’s (absorption, digestion, uptake) responses to 10 paired foods at 3 different dose levels (high, medium, zero). The 10 test foods include chicken, beef, salmon, whole wheat bread, oats, potatoes, corn, cheese, soybeans (tofu/tempeh), and yogurt. The body’s response to a pair of test food will be measured over three separate 8 day-controlled feeding periods. During each feeding period a pair of test food will be consumed, as part of a regular diet, in high, medium, and zero amounts. During the feeding periods all meals, snacks, and most beverages are provided.

What to expect

• 12 in-person visits over 2-3 months-including food pickups (9) and clinic visits (3)
• Food pick ups and study visits in Boston
• Questionnaires, blood, urine, and stool samples
• Daily food record keeping
• Eat a prescribed diet for 8 days- Example menu VIEW HERE