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Center for Climate, Health, and the Global Environment

We seek climate solutions that can provide for a healthier and more just world today and a livable future for our children.

Location

665 Huntington Avenue 
Building 1, Room 1312 
Boston, MA 02115

Helping COPD patients breathe easier

Research team for the Air Purification for Eosinophilic COPD Study

Federal funding for this project was terminated in May 2025. We are actively fundraising to continue the work.

Impact level: Individuals

Location: Boston 

What problem are we trying to solve? 

Chronic obstructive pulmonary disease (COPD) is an incurable and deadly disease that affects 15% of adults over 40 years of age in the United States and is made worse by exposure to air pollution. COPD is the third most common cause of death in the United States. We have found that people with eosinophilic COPD, an inflammatory subtype affecting more than a third of COPD patients, are more susceptible to air pollution. 

What climate and health solution are we researching? 

We are using a randomized control trial—the “gold standard” for testing interventions—to test whether high efficiency particulate air (HEPA) purifiers improve symptoms and lung function in people with eosinophilic COPD.   

What’s the level of impact?

This solution may improve individual patients’ lives and provide a potential low-risk, non-drug intervention that may prevent airborne triggers of COPD symptoms, such as traffic pollution, allergens, and smoke. If the evidence supports their use, HEPA filters could be covered by medical insurance as durable medical equipment, much like supplemental oxygen or nebulizer machines. 

Who will this research benefit? 

This research aims to improve the health of eosinophilic COPD patients by reducing their exposure to particles that worsen airway inflammation, potentially providing a way to reduce the need for costly medications.  

Where is the research happening? 

Global map pointing to Boston, Massachusetts
Boston, Massachusetts

Learn more

To learn more about this clinical trial, contact Anna Miller.

C-CHANGE team