Department of Molecular Metabolism
Researching the complex interplay between the major factors underlying metabolic health and disease, including diet, age, environment, and genetics, for the prevention and treatment of widespread chronic diseases.
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News
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June 9, 2023
Sympathetic tone dictates the impact of lipolysis on FABP4 secretion
In a paper published in the Journal of Lipid Research, Kacey Prentice, PhD, and a group of scientists from the Hotamışlıgil Lab at the Sabri Ülker Center demonstrated that secretion…
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Infectious Diseases May 22, 2023
Unlocking cellular secrets to better treat diseases
Sophie Lockwood, PhD ’23, uncovered a complex biological mechanism that could potentially help in drug development.
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May 12, 2023
Mitochondrial morphology controls fatty acid utilization by changing CPT1sensitivity to malonyl-CoA
In a paper published in the EMBO Journal in February, the Danial (Molecular Metabolism/ Dana Farber Cancer Institute) and Shirihai (UCLA) labs reported that fatty acid utilization is selectively coupled…
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January 20, 2023
Zachary Nagel promoted to Associate Professor of Genomics and Cancer Biology
Dear Members of the Harvard Chan School Community: Please join me in congratulating Zachary Nagel on his promotion to Associate Professor of Genomics and Cancer Biology in the Department of…
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January 5, 2023
mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species
In a recent paper published in Nature Metabolism mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species, Department of Molecular Metabolism postdoctoral fellow Aaron Hosios and other colleagues in…
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November 17, 2022
Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
In a paper published in iScience, Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex, from the Laboratory of Professor Brendan Manning, MollyMcNamara Goodrich…
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Food, Nutrition, Diet June 14, 2022
Alexander Banks recognized for excellence in endocrine research
Alexander Banks received the 2022 Armen H. Tashjian Jr. Award for Excellence in Endocrine Research for his work to standardize data analysis in obesity research.
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Chronic Diseases March 9, 2022
Obesity alters molecular architecture of liver cells; repairing structure reverses metabolic disease
Cells use their molecular architecture to regulate their metabolic functions, and repairing diseased cells’ architecture to a healthier state can also repair metabolism, according to a study led by Harvard T.H. Chan School of Public Health researchers.
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Cancer December 10, 2021
Newly identified hormone may be a critical driver of type 1 and type 2 diabetes
A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to research led by the Sabri Ülker Center for Metabolic Research at Harvard Chan School.
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Chronic Diseases November 17, 2021
Hidden in plain view
Bob Farese Jr. is an expert in how lipid synthesis and storage may lead to disease—and an accomplished amateur photographer.
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