Department of Molecular Metabolism
Researching the complex interplay between the major factors underlying metabolic health and disease, including diet, age, environment, and genetics, for the prevention and treatment of widespread chronic diseases.
665 Huntington Avenue
Building 2, 1st Floor
News
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October 5, 2023
Endothelial FABP4 constitutes the majority of basal circulating hormone levels and regulates lipolysis-driven insulin secretion
In a paper published in JCI Insight, titled, “Endothelial FABP4 constitutes the majority of basal circulating hormone levels and regulates lipolysis-driven insulin secretion”, a team of researchers from the Hotamışlıgil…
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October 5, 2023
Neuronal mTORC1 inhibition promotes longevity without suppressing anabolic growth and reproduction in C. elegans
In a recent paper published in PLoS Genetics, Dr. Mair and his team led by Hannah Smith, demonstrated that selectively inhibiting mechanistic target of rapamycin complex 1 (mTORC1) in neurons…
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Chronic Diseases September 14, 2023
Department of Molecular Metabolism celebrates 20th anniversary
Over 100 current and former members of Harvard T.H. Chan School of Public Health’s Department of Molecular Metabolism gathered on September 7 to celebrate the 20th anniversary of the department’s founding, to reflect on the successes of the past two decades, and to look ahead to promising research in the field of metabolism.
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June 30, 2023
Quad Garage Advisory- WAB Promenade Project and Quad Garage Ramp
Department Representatives, Due to the WAB Promenade Project, the Quad garage ramp will be reduced to one lane at all times starting on Thursday, June 15th. The project is expected…
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June 30, 2023
New European Union Shipping/Import Regulations Effective March 1st, 2023
Dear Department Administrators and Associate Directors of Finance: Please share this important shipping information with all shippers in your Harvard Chan Departments. The European Union (EU) is implementing a new…
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June 9, 2023
Sympathetic tone dictates the impact of lipolysis on FABP4 secretion
In a paper published in the Journal of Lipid Research, Kacey Prentice, PhD, and a group of scientists from the Hotamışlıgil Lab at the Sabri Ülker Center demonstrated that secretion…
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Infectious Diseases May 22, 2023
Unlocking cellular secrets to better treat diseases
Sophie Lockwood, PhD ’23, uncovered a complex biological mechanism that could potentially help in drug development.
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May 12, 2023
Mitochondrial morphology controls fatty acid utilization by changing CPT1sensitivity to malonyl-CoA
In a paper published in the EMBO Journal in February, the Danial (Molecular Metabolism/ Dana Farber Cancer Institute) and Shirihai (UCLA) labs reported that fatty acid utilization is selectively coupled…
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January 20, 2023
Zachary Nagel promoted to Associate Professor of Genomics and Cancer Biology
Dear Members of the Harvard Chan School Community: Please join me in congratulating Zachary Nagel on his promotion to Associate Professor of Genomics and Cancer Biology in the Department of…
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January 5, 2023
mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species
In a recent paper published in Nature Metabolism mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species, Department of Molecular Metabolism postdoctoral fellow Aaron Hosios and other colleagues in…
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