Rubin Lab
Tuberculosis (TB) kills 1.3 million people each year. Our research on Mycobacterium tuberculosis focuses on its cell biology and how it causes TB, to develop new therapies. We also study non-tuberculous mycobacteria (NTM), as cases are increasing in number and hard to treat, aiming to discover new treatments through advanced research tools.
Harvard T.H. Chan School of Public Health
665 Huntington Ave.
Building 1, Room 810
Boston, MA 02115
Our Team
Eric Rubin
Since the Circus closed, Eric Rubin has devoted full time to research and medicine. He is a tuberculosis researcher at the Harvard T.H. Chan School of Public Health, an infectious disease specialist at the Brigham and Women’s Hospital, and Editor-In-Chief at the New England Journal of Medicine.
For scheduling requests for Dr. Rubin, please contact Maria Sedjo at the New England Journal of Medicine.
Researchers
Tatos is working on the Clp protease system of Mycobacterium tuberculosis (Mtb) – a high priority target for drug development.
Emmy handles managerial responsibilities for the lab. These include ordering supplies, managing safety trainings, maintaining equipment, and shipping materials to collaborators.
Kristi (not a slave to fashion) Guinn has been keenly interested in TB since 2000. She did her Master’s work studying genetic determinants of pathogenicity, and migrated away from the bench shortly thereafter to try her hand at project management. She has happily remained in this capacity, joining the Rubin Lab in 2011.
Mohlopheni (Jackson) is interested in host factors that drive lung granuloma progression in TB patients. He is also interested in genes utilized by M. tuberculosis to subvert macrophage killing effects. Office: University of Cape Town, Cape Town, South Africa.
Tetiana comes to HSPH with a background in medicinal chemistry and small molecules synthesis, working recently in a contract research organization on integrated projects for 9 years. Her passion is working on integrated projects combining synthetic chemistry, biology, and computational chemistry.
Ian’s research focuses on genes of unknown function in tuberculosis.
Office: Chinese Academy of Sciences, Beijing, China.
Postdoctoral Fellows
Kritee comes to HSPH with a strong interest in understanding infectious disease biology. She has a background of zoology and biomedical research from University of Delhi, India. Kritee completed her Ph.D. studies exploring Mycobacterium tuberculosis secondary metabolism from CSIR-Institute of economics and Integrative Biology, New Delhi, India. Outside of work, Kritee enjoys baking, crafting, reading for leisure and of course, eating spicy food.
Sille has experience in microbiology and structural biology. She is interested in the inner workings of the mycobacterial cell envelope as well as drug resistance mechanisms in M. abscessus.
Mark is studying Mycobacterium abscessus lung infection through the use of tissue culture model systems.
Students
