Tatos Akopian

Biography

Publications

• Targeted protein degradation in mycobacteria uncovers antibacterial effects and potentiates antibiotic efficacy.

  Won HI, Zinga S, Kandror O, Akopian T, Wolf ID, Schweber JTP, Schmid EW, Chao MC, Waldor M, Rubin EJ, Zhu J. Nat Commun 2024 May 14

• Correction: Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.

  Weinhäupl K, Gragera M, Bueno-Carrasco MT, Arranz R, Krandor O, Akopian T, Soares R, Rubin E, Felix J, Fraga H. J Biol Chem 2023

• Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.

  Weinhäupl K, Gragera M, Bueno-Carrasco MT, Arranz R, Krandor O, Akopian T, Soares R, Rubin E, Felix J, Fraga H. J Biol Chem 2022 11

• ClpX Is Essential and Activated by Single-Strand DNA Binding Protein in Mycobacteria.

  Kester JC, Kandror O, Akopian T, Chase MR, Zhu J, Rubin EJ, Goldberg AL, Fortune SM. J Bacteriol 2021 01 25

• Pyrazinamide triggers degradation of its target aspartate decarboxylase.

  Gopal P, Sarathy JP, Yee M, Ragunathan P, Shin J, Bhushan S, Zhu J, Akopian T, Kandror O, Lim TK, Gengenbacher M, Lin Q, Rubin EJ, Grüber G, Dick T. Nat Commun 2020 04 03