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The Mair lab investigates why aging increases susceptibility to chronic diseases. We explore how nutrition and environment affect aging rates, noting benefits of fasting and reduced food intake in extending health span across species. We study genetic pathways linking metabolism and aging, aiming to replicate benefits of dietary restriction without its drawbacks. Our research spans from yeast to humans, leveraging evolutionary conservation to understand and potentially mitigate human aging processes. 

Location

665 Huntington Avenue
Building 1, Room 509
Boston, MA 02115 

Meet Our Team

William Mair, Ph.D.

Dr. Mair is a Professor of Molecular Metabolism at Harvard and Director of the Harvard T.H. Chan Healthy Aging Initiative. As Director, he leads a multidisciplinary effort to extend human healthspan by identifying the drivers of age-related disease and developing interventions to help people worldwide spend more years in good health.

He received his BSc in Genetics and PhD in Biology from University College London, and completed his postdoctoral training at the Salk Institute for Biological Studies in La Jolla, CA. The Mair lab studies mechanisms that mitigate the risks of aging, focusing on metabolism and how changes to food intake impact the aging process. They are defining how nutrient and energy sensors in cells become dysfunctional with age, leading to metabolic inflexibility and accelerated aging. Dr. Mair’s work aims to develop therapeutics that maintain healthy metabolic function, thereby enabling our bodies to process food effectively as we age.

William Mair Headshot

Dr. Mair has won numerous awards for his work on aging and geroscience, including the American Federation Breakthrough in Gerontology Award, the Glenn Medical Foundation for Medical Research Scholar Award, and the Ellison Medical Foundation New Scholar in Aging Research Award. He is co-founding director of the MBL Biology of Aging Summer Research Course, and organizes several international conferences on geroscience and aging biology.

Lab Manager

Postdoctoral Fellow

Research Assistant

Lab Lab

Lab Alumni

Arpit Sharma
Postdoctoral Fellow

Peter Stine
Lab Assistant

Miriam Valera-Alberni
Postdoctoral Fellow

Maria Perez Matos
Graduate Student

Hannah Smith
Graduate Student

Ewelina Nowak
Graduate Student

Noel Jackson
Graduate Student

Carlos Silva Garcia
Visiting Scientist

Carlos Vergani
Visiting Graduate Student

Lourdes Pajuelo
Postbaccalaureate Student

Pallas Yao
Graduate Student

Laura Wester
Postdoctoral Fellow

Sam Lapp
Graduate Student

Vanessa Laversenne
Postdoctoral Fellow

Caroline Heintz
Research Associate

Sneha Dutta
Graduate Student

Andrew Larocque
Lab Assistant

Malini Bhadra
Postdoctoral Fellow

Porsha Howell
Postdoctoral Fellow

Dana Fleischhauer
Visiting Graduate Student

Pallavi Joshi
Rotation Student

Rohan Sehgal
Research Assistant

Kristopher Burkewitz
Charles A. King Trust Postdoctoral Fellow

Roy Chowdhury
Postdoctoral Fellow

Emina Tabakovic
Research Assistant

Nicole Clark
Research Assistant

Caroline Escoubas
Graduate Student

Yue Zhang
Graduate Student

Alex Plesa
Rotation Student

Anita Reddy
Rotation Student

Heather Weir
Postdoctoral Fellow

Ryann Guayasamin
Postdoctoral Fellow

Obichi Onwukwe
Undergraduate Summer Student

Sydney Brumfield
Undergraduate Researcher

Iris Lee
Visiting Masters Student

Zhouwei Zhang
BPH Rotation Student

Juan Ramirez
Undergraduate Researcher

Kaitlyn Izzo
Undergraduate Researcher

Ibrahim Kurt
BPH Rotation Student

Staci Thornton
Undergraduate Summer Student

Raymond A. Laboy Morales
Undergraduate Summer Student

Ianessa Morantte
Research Specialist/Lab Manager

Jim Valcourt
BBS Rotation Student

Joseph Beyene
BPH Rotation Student

Robin Yeo
Research Assistant

Jee Yun Kim
Undergraduate Summer Student

Ana Paula Morales Allende
Undergraduate Summer Student

Elissa Lin
Undergraduate Summer Student

Kasia Baranowski
BPH Rotation Student

Tinatini Tavhelidse
Visiting Masters Student

How to join the Lab

How to join the Lab 

We are often looking for new Mair Lab members, if you are interested in joining our lab family, please email your CV to William at wmair@hsph-harvard-edu.
Common positions include: Postdoctoral Fellow, Research Assistant, Undergraduate Research Assistant, Summer Intern.