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Mahalingaiah Lab

A dynamic team of students and researchers led by Dr. Shruthi Mahalingaiah
using digital platforms to understand environmental, reproductive, and women’s health.

Location

677 Huntington Avenue
Boston, MA 02115

Research Studies

Explore the current studies in the Mahalingaiah Lab. These studies are either enrolling, in data analysis or are recently completed.

Enrolling Studies

Apple Women’s Health Study

The study aims to understand how certain demographic and lifestyle factors could have an impact on menstrual cycles and gynecologic conditions including infertility, menopause, and polycystic ovary syndrome (PCOS). Visit the study website.

The PREPARE Study

This study investigates the association between maternal and paternal preconception exposure to PFAS (also called “forever chemicals”) and reproductive, pregnancy, and birth outcomes. The study aims to evaluate this relationship using serum PFAS concentrations collected throughout the preconception, prenatal, and postnatal periods from participants. Additional information is collected regarding important fertility markers. Visit the study website.

Data Analysis

MAGNOLIA

This study aims to understand the impact of endocrine-disrupting chemicals (EDCs) on menstrual cycle characteristics, which are a vital sign of health. The MAGNOLIA study will specifically focus on individuals who frequently use nail products to explore these questions further. For more information on the study, please visit this link.  

R01

The study’s goal is to fill a major gap in our understanding of the effect of air pollution and environmental exposures on menstrual health and disease. The findings may help inform clinical counseling on health promotion and risk reduction across the lifespan to support menstrual health.

Recently Completed

The Beauty Edit Study

This study educates people on common endocrine-disrupting chemicals (EDCs), for example phthalates, on the reproductive and endocrine system. Additionally, the study aims to assess the use of personal care products containing these chemicals, as well as characterize knowledge and attitudes about personal care product use, the chemicals, and their impact on health. For more information on the study, please visit this link.   

PEONY

This study is a personalized smartphone-based assay for at-home ovulation prediction. The study’s aim is to develop an ovulation kit empowered by AI that uses salivary ferning for ovulation detection and tracking even in women with polycystic ovarian syndrome (PCOS) who may not have accurate results through the standard urinary detection methods.

APRICOT

ART Provider and Patient Resource to Improve Communication about Outcomes and Treatment (APRICOT)

The study aims to design and evaluate a health information technology application to help fertility clinics collect pregnancy outcome information more efficiently from previous assisted reproductive technology (ART) patients and their healthcare providers.

COVID-19 and Menstrual Cycles Study

The study observed how factors related to the COVID-19 pandemic impacted menstrual cycles.

Menstruation Animation

Our team collaborated with the Museum of Science, Boston at the Living Laboratory®, with the efforts led by Dr. Susan Heilman, to display the animation as an exhibit in the summer of 2022. During that time, 150 people watched the animation, and 50 families participated in a survey about their knowledge, attitudes, and beliefs about menstruation.