Kory Lab
The Kory Lab is studying nutrient transport and metabolic compartments in cells, like mitochondria, and their roles in health and disease, such as inborn errors of metabolism, inflammatory and neurological diseases, cancer, and diabetes.
655 Huntington Ave
Building 1, Room 512
Boston, MA 02115
The Kory Lab
The Kory Lab led by Dr. Nora Kory focuses on how cellular organelles including mitochondria –cellular powerhouses and biosynthetic factories– exchange metabolites with the rest of the cell while maintaining their unique chemical environment. Motivated by the consequences of altered metabolism and mitochondrial dysfunction on diseases like cancer, neurodegeneration and diabetes, our overarching goals are to understand how alterations in nutrient transport influence human health and disease and to leverage this knowledge for therapeutic development. We combine functional genomics, metabolite profiling, imaging, cell biology, and biochemistry approaches to address these questions at the molecular and physiological levels and use transport proteins as tools to interrogate metabolic and signaling pathways to understand how mitochondria perform their roles in maintaining metabolic homeostasis.
