Skip to main content

Lee Kum Sheung Center for Health and Happiness

The mission of the Lee Kum Sheung Center for Health and Happiness is to build a rigorous and interdisciplinary science of positive health, happiness, and well-being with a focus on health equity, and to translate the science to influence practice and policy.

Location

Kresge Building 6th Floor
677 Huntington Avenue
Boston, MA 02115

book

Publications

Center scholars and affiliate scientists are continuously investigating the complex interrelationships between physical, social, and mental health and designing and evaluating interventions for the improvement of overall well-being across the globe. Besides the connections between these three realms of health, key areas of focus include health equity, social media, loneliness, resilience, and positive psychology.

Research by Center Scholars and Affiliates 2024-5

Abe, K., Suzuki, K., Miyawaki, A., & Kawachi, I. (2025). Impact of COVID-19 on medical utilization for psychiatric conditions in Japan. Social Science & Medicine, 367

Duncan, D.T., Kawachi, I., and Morse, S.S. (2024). The Social Epidemiology of the COVID-19 PandemicOxford University Press  

Durieux, N., Park, E. R., Hall, D., Meek, J., Fricchione, G., Mehta, D. H., & Luberto, C. (2025). Resiliency among Mass General Brigham Hospital employees post-COVID-19 pandemic. Global Advances in Integrative Medicine and Health

Kawachi, I. (2024). Income Inequality and COVID-19, in Duncan, D., Kawachi, I., and Morse, S. (2024). The Social Epidemiology of the COVID-19 Pandemic. Oxford University Press, USA

Chakraborty, S., Gui, M., Gerosa, T., and Marciano, L. (2024). Testing the validity of the smartphone pervasiveness scale for adolescents with self-reported objective smartphone use data. Digital Health, 10: 1-9  

Patel, V., et al. (2025). Task-sharing and telemedicine delivery of psychotherapy to treat perinatal depression: A pragmatic, noninferiority randomized trial. Nature Medicine

Patel, V., et al. (2024). Scaling up the task-sharing of psychological therapies: A formative study of the PEERS smartphone application for supervision and quality assurance in rural IndiaCambridge Prisms: Global Mental Health, 11(20), 1–11  

Patel, V., et al. (2024). Designing an App to Support Measurement-Based Peer Supervision of Frontline Health Workers Delivering Brief Psychosocial Interventions in Texas: Multimethod StudyJMIR Formative Research, 8  

Patel, V., et al. (2024). Development and Pilot Testing of PracticePal, a Conversational Agent to Support the delivery of a brief behavioural activation treatment for depression in rural India. Springer Nature

Pedersen, G., & Patel, V., et al. (2024). Development of a Remote Implementation Support Strategy to Enhance Integration of Depression Treatment into Primary Care Settings in Rural India. Frontiers in Public Health, 12

James, P., et al. (2024).Measuring Environmental and Behavioral Drivers of Chronic Diseases Using Smartphone-Based Digital Phenotyping: Intensive Longitudinal Observational mHealth Substudy Embedded in 2 Prospective Cohorts of Adults. JMIR Public Health and Surveillance

Denckla, C.A, Kubzansky, L.D., Koenen, K.C., et al. (2024). A systematic review of the effects of chronic, slow-onset climate change on mental healthNature mental health  

James, P., et al. (2025). Seasonal average temperature differences and CVD incidence: Results from the US-based Nurses’ Health Study, Nurses’ Health Study II, and the Health Professional Follow-up study. Environmental Health Perspectives

James, P., et al. (2024). Associations of street-view greenspace with Parkinson’s disease hospitalizations in an open cohort of elderly US Medicare beneficiaries. Environment International,188

James, P., et al. (2024). Abstract MP76: Street View Greenspace Exposures and Cardiovascular Health Among Children – Evidence From Project Viva. AHA Journals

James, P., et al. (2024). Abstract P394: Associations of Street-View Greenspace Exposure With Cardiovascular Health (Life’s Essential 8) Among Women in Midlife. AHA Journals

James, P., et al. (2024). Childhood exposure to air pollution, noise, and surrounding greenness and incident hypertension in early adulthood in a US nationwide cohort–the Growing Up Today Study (GUTS). Environmental Research, 263 (2)

Koenen, K.C., et al. (2025). Associations between residential segregation, ambient air pollution, and hippocampal features in recent trauma survivors

Patel, V., et al. (2024). Advancing disability-inclusive climate research and action, climate justice, and climate-resilient development. The Lancet: Planetary Health, 8(4), E242-E255

Schwartz, J., et al. (2024). Air pollution mixture exposure during pregnancy and postpartum psychological functioning: racial/ethnic- and fetal sex-specific associations. Journal of Exposure Science & Environmental Epidemiology

Krekel, C., Kavetsos, G., & Ziebarth, N. R. (2025). Passing on the flame: Do mega sports events promote health behaviours? Social Science & Medicine

Marciano, L., Kikut-Stein, A., & Viswanath, K. (2025). Communication, equity, and mental well-being: The road ahead. In M. C. Yzer & J. T. Siegel (Eds.), The handbook of mental health communication (1st ed.). John Wiley & Sons, Inc.

National Academies of Sciences, Engineering, and Medicine. (2024). Understanding and Addressing Misinformation About Science. (Viswanath, K., Taylor, T., and Rhodes, H., Eds.) Washington, DC: The National Academies Press

Adzrago, D., Elhabashy, M., Williams, D. R., & Williams, F. (2025). Psychological distress and its potential risk factors among Black and White adult immigrants in the United States – National Health Interview Survey 2005–2018. Preventive Medicine Reports, 103052

Cajita, M., Dunn, S., Hernandez, R., & Doorenbos, A. (2024). Abstract 4123509: The Intersection of Race and Ethnicity, Social Determinants of Health, and Hypertension Prevalence: A Community-Level Analysis. Circulation, 150

Denckla, C. A., et al. (2025). Multi-level socioeconomic modifiers of the comorbidity of post-traumatic stress and tobacco, alcohol, and cannabis use: The importance of income. Social Psychiatry and Psychiatric Epidemiology

Grodstein, F., et al. (2025). Sexual orientation disparities in subjective cognitive decline in a large cohort of female nurses. LGBT Health

Grodstein, F., et al. (2024). Everyday Discrimination is Associated with Higher Odds of Hospitalizations among Older African Americans. The Journals of Gerontology: Series A  

Lawrence, J., Hsu, Y., Cory, H., & Kawachi, I. (2024). Racial discrimination and cognitive function: An instrumental variable analysis. Social Science & Medicine, 363

Mateo, C.M., Furtado, K., Plaisime, M.V., and Williams, D.R. (2024). The Sociopolitical Context of the Unequal Treatment Report: Then and Now. Urban Institute

Mbewu, A., Williams, D.R., Moletsane, R., and Reddy, P. (2024). Striking racial inequities in health persist in South Africa. BMJ, 385, q834

Peters, S.E., Wagner, G.R., et al. (2024). Adding injury to insult: Unfair treatment at work and occupational injury among hospital patient-care workers. American Journal of Industrial Medicine

Pinillos-Franco, S. & Kawachi, I. (2025). It’s not just your opinion, it’s a type of hate that may affect your health: the effect of homophobia on health in Europe

Qureshi, F., Denckla, C., and Boehm, J.K. (2024). Positive epidemiology, revisited: The case for centering human rights and economic justice. American Journal of Epidemiology

Williams, D.R., et al. (2024). Addressing Structural Racism Through Public Policy Advocacy: A Policy Statement From the American Heart AssociationAmerican Heart Association Journal

Ramanadhan, S., et al. (2025). Assessing equitable implementation of a social care initiative integrating medical and social services for Medicaid members. Health Services Research

Rastogi, R., Raval, V. V., Yip, T., Chen, J. A., & Liu, C. H. (2025). The effects of racial exclusion and racial othering on South Asian American identity and population health. American Journal of Public Health

Semanaz, C., Ghassabian, A., Delaney, S., Fang, F., Williams, D. R., & Tiemeier, H. (2025). Considerations when accounting for race and ethnicity in studies of poverty and neurodevelopment. Journal of the American Academy of Child & Adolescent Psychiatry

Wright, E., Dore, E. C., Koenen, K. C., Mangurian, C., Williams, D. R., & Hamad, R. (2025). Prevalence of and inequities in poor mental health across 3 US surveys, 2011 to 2022. JAMA Network Open, 8(1)

Cowden, R.G., et al. (2024). Do Forgiveness Campaign Activities Improve Forgiveness, Mental Health, and Flourishing? International Journal of Public Health, 69

Kim, E. S., Bradshaw, M., Chen, Y., Chopik, W. J., Okuzono, S. S., Wilkinson, R., Padgett, R. N., Lachman, M. E., Johnson, B. R., & VanderWeele, T. J. (2025). Characterizing the Childhood Roots of Adult Sense of Mastery Across 22 Countries in the Global Flourishing Study

Kim, E. S., Padgett, R. N., Bradshaw, M., Chen, Y., Chopik, W. J., Okuzono, S., Wilkinson, R., Lachman, M. E., Johnson, B. R., & VanderWeele, T. J. (2025). Mapping demographic variations in sense of mastery across the world: A cross-national analysis of 22 countries in the Global Flourishing Study

Kim, E. S., Wilkinson, R., Holt-Lunstad, J., & VanderWeele, T. J. (2025). Loneliness During Adolescence and Subsequent Health and Well-Being in Adulthood: An Outcome-Wide Longitudinal Approach.  Journal of Adolescent Health

Kim, E.S., et al. (2024). The silent epidemic of loneliness: identifying the antecedents of loneliness using a lagged exposure-wide approachPsychological Medicine, 1–14

Wilkinson, R., Shiba, K., Kim, E. S., Case, B., Okuzono, S., Cowden, R., Gundersen, C., Chen, Y., Padgett, R. N., Johnson, B. R., & VanderWeele, T. J. (2025). Loneliness in a global context: Sociodemographic disparities and childhood determinants

Yoshida, K., Honda, K., Goto, A., and Kawachi, I. (2024). Collateral Health Effects of Loneliness Care in Japan. Health Services Research and Managerial Epidemiology

Choi, K., et al. (2024). Genetic architecture and socio-environmental risk factors for major depressive disorder in Nepal. Psychological Medicine, 54 (11)

Choi, K., et al. (2024). Time Trends in Adolescent Diagnoses of Major Depressive Disorder and Co-occurring Psychiatric Conditions in Electronic Health Records. Research Square 

Kawachi, I., et al. (2024). Pre-disaster income inequality and post-disaster mental health: A natural experiment from the 2011 Great East Japan Earthquake and Tsunami . Health & Place, 90

Papola, D. & Patel. V. (2025). Towards person-centered care in global mental health: implications for meta-analyses and clinical trials. Epidemiology and Psychiatric Sciences 34, e13, 1–5

Patel, V., et al. (2025). Effective components of collaborative care for depression in primary care: An individual participant data meta-analysis. JAMA Psychiatry

Patel, V., et al. (2024). Adapting and deploying a digital program for training non-specialist providers on a brief psychological intervention for depression in rural Gujarat, India. PLOS Global Public Health

Patel, V., et al. (2024). Depression Diagnosis, Treatment, and Remission Among Adults in India. JAMA Psychiatry

Patel, V., et al. (2024). Remote coaching for supporting the implementation of treatment for depression in primary care in Madhya Pradesh, India: protocol for a cluster randomized controlled trial. Frontiers in Health Services

Patel, V., et al. (2024). Adolescent engagement in a stepped care, transdiagnostic mental health intervention delivered in Indian schools. Discover Psychology, 4:43

Patel, V., et al. (2024). The Effects of Mental Health Interventions on Labor Market Outcomes in Low- and Middle-Income Countries. National Bureau of Economic Research

Patel, V., et al. (2024). International Representation in Psychiatric Literature: Has the Trend Changed? Review of 11 Leading Psychiatric Journals. Archives of Psychiatry Research, 60:1

Williams, D.R., et al. (2025). Treatment coverage for mental disorders: Results from the World Health Organization World Mental Health Surveys. In Oxford textbook of community mental health (2nd ed., pp. 45-56). Oxford University Press

Côté, A., Miquelon, P., and Trudel-Fitzgerald, C. (2024). Physical Activity, Sedentary Time, and Psychosocial Functioning among Adults with Cancer: A Scoping ReviewInternational Journal of Environmental Research and Public Health, 21(2), 225

Hernandez, R., et al. (2024). Depressive Symptoms, Antidepressants, and Clinical Outcomes in Chronic Kidney Disease: Findings from the CRIC StudyKidney Medicine, 6(4)

Kim, E.S., Wilkinson, R., Okuzono, S.S., Chen, Y., Shiba, K., Cowden, R.G., and VanderWeele, T.J. (2024). Positive affect during adolescence and health and well-being in adulthood: An outcome-wide longitudinal approach. PLOS Medicine

Kivimäki, M., & Kawachi, I. (2025). Work stress and health. In N. Schneiderman, T. W. Smith, N. B. Anderson, M. H. Antoni, F. J. Penedo, T. A. Revenson, & A. F. Abraído-Lanza (Eds.), APA handbook of health psychology, Vol. 1. Foundations and context of health psychology (pp. 611–637). American Psychological Association.

Koenen, K., et al. (2024). Identifying Genetically Inferred Effects Linking Posttraumatic Stress Disorder to Women’s Health, Lipid Disorders, and Malaria Medications. American Journal of Psychiatry, 181(12)

Koenen, K., et al. (2024). No association of posttraumatic stress disorder with epigenetic aging in women at mid-life: A longitudinal cohort study. Brain, Behavior, and Immunity, 123, 672-680

Ng, A. E., Gruenewald, T., Juster, R.-P., & Trudel-Fitzgerald, C. (2025). Affect regulation and mortality risk: The role of allostatic load. Biopsychosocial Science and Medicine

Patel, V., et al. (2024). Conditional cash transfers and mortality in people hospitalised with psychiatric disorders: A cohort study of the Brazilian Bolsa Família Programme. PLOS Medicine

Patel, V., et al. (2024). Effectiveness, cost-effectiveness, and positive externalities of integrated chronic care for adults with major depressive disorder in Malawi (IC3D): a stepped-wedge, cluster-randomised, controlled trial . The Lancet, 404(10465)

Trudel-Fitzgerald, C., et al. (2024). Understanding mental health in breast cancer from screening to Survivorship: an integrative phasic Model and tool. Psychology, Health, & Medicine

Park, E., et al. (2024). Residents’ perspectives on program impact of a group-based mind-body intervention in CCRCS. Innovation in Aging

Perez, G.K., Park, E.R., et al. (2024). Development and feasibility of a virtual, synchronous mind-body resiliency intervention for fathers of children and youth with special healthcare needs. Brain Behavior and Immunity Integrative, 5

Wayne, P. M., Ahn, A., Clark, J., Irwin, M. R., Kong, J., Lavretsky, H., Li, F., & Yeh, G. Y. (2025). The science of Tai Chi and Qigong and whole person health part I: Rationale and state of the science. Journal of Integrative and Complementary Medicine

Wayne, P., et al. (2024). Tai Chi for balance and postural control in people with peripheral neuropathy: A scoping review. Complementary Therapies in Medicine

Yeh, G., et al. (2025). Pilot study protocol for a novel perioperative mind-body intervention for peripheral vascular interventions. JVS-Vascular Insights, 3, 100199. Presented at the 52nd Annual Meeting of the Society for Clinical Vascular Surgery, March 28, 2025, Austin, Texas

Joss, D., Teicher, M.H., and Lazar, S.W. (2024). Beneficial effects of mindfulness-based intervention on hippocampal volumes and episodic memory for childhood adversity survivorsJournal of Affective Disorders Reports, 16  

Lazar, S.W., et al. (2024). ENIGMA-Meditation: Worldwide consortium for neuroscientific investigations of meditation practices  

Lazar, S., et al. (2024). Neural correlates of reduction in self-judgment after mindful self-compassion training: A pilot study with resting state fMRI. Journal of Mood and Anxiety Disorders, 9

Luberto, C., Crute, S., Wang, A., Li, R., Yeh, G., Huffman, J., Celano, C., Victorson, D., Hoeppner, B., & Park, E. (2024). Needs and Preferences for Remote-Delivered Mindfulness-Based Cognitive Therapy in Patients After Acute Coronary Syndrome: A Qualitative Study. Global Advances in Integrative Medicine and Health, 13, 1-10

Wayne, P.M., Yeh, G.Y., and Mehta, D.H. (2024). Through the Looking Glass: Psychedelics As a Window into Mindfulness and Mind–Body HealthJournal of Integrative and Complementary Medicine, 30: 1

Chen, Y., Nakamura, S., Kim, E., Kubzansky, L., & VanderWeele, T. (2024). Changes in optimism and subsequent health and wellbeing outcomes in older adults: an outcome-wide analysis.  Aging & Mental Health

Huffman, J.C., et al. (2024). Gratitude, optimism, and satisfaction with life and patient-reported outcomes in patients undergoing hematopoietic stem cell transplantationPsycho-Oncology, 33 (2)

Koga, H.K., Grodstein, F., Williams, D.R., et al. (2024). Longitudinal Associations Between Optimism and Objective Measures of Physical Functioning in WomenJAMA Psychiatry

Oh, J., Tetreau, E., Purol, M., Kim, E., & Chopik, W. (2024). Optimism and pessimism were prospectively associated with adaptation during the COVID-19 pandemic. Journal of Research in Personality, 113

Choi, K., et al. (2025). Multisystemic resilience and its impact on youth mental health: Reflections on co-designing a multi-disciplinary, participatory study. Frontiers in Child and Adolescent Psychiatry, 4

Choi, K., et al. (2025). Psychometric properties and socio-demographic correlates of the Connor-Davidson Resilience Scale in three large population-based cohorts including Danish and Icelandic adults. Journal of Mood & Anxiety Disorders

Dijk, S. W., Krijkamp, E., & Hunink, M. (2025). Economic evaluation of resilience training for medical students: A cohort state-transition model. Medical Teacher

Kawachi, I., et al. (2024). Resilience factors affecting long-term trajectories of depressive symptoms in the aftermath of the Great East Japan Earthquake and Tsunami among older adults. The Journals of Gerontology

Park, E., et al. (2024). B – 97 On the Rebound: Resilience and Subjective Cognitive Concerns in Cancer | Archives of Clinical Neuropsychology. Archives of Clinical Neuropsychology, 39(7),1197

Park, E., et al. (2024). A resiliency intervention adapted for older women with HIV: Results from a pilot randomized controlled trial in the northeastern US. Journal of Health Psychology  

Sampson, L., Scoglio, A. A. J., Nishimi, K., Choi, K., Kim, A. H., Zhu, Y., Sun, Q., Kang, J. H., Rimm, E. B., Koenen, K. C., & Kubzansky, L. D. (2025). Psychological resilience to trauma and longitudinal sleep outcomes among current and former nurses. Journal of Psychosomatic Research, 192, 112090

Scoglio, A., Nishimi, K., Choi, K., Koenen, K., Sampson, L., Jha, S., and Kubzansky, L. (2024). Prior resilience to trauma & coping during the COVID-19 pandemic. PLOS One  

Yeh, G., Park, W., et al. (2024). Pilot Randomized Controlled Trial of IN FOCUS: A Mind‐Body Resiliency Intervention for Fear of Cancer Recurrence . Psycho-Oncology, 33(11)

Kim, E. S., Bradshaw, M. ,Padgett, R. N., Chen, Y., Shiba, K., Ritchie-Dunham, J. L., Case, B. W., Johnson, B. R., & VanderWeele, T. J. (2025). Identifying Childhood Correlates of Adult Purpose and Meaning Across 22 Countries (Global Flourishing Study)

Kim, E., et al. (2024). Measuring meaning in life by combining philosophical and psychological distinctions: Psychometric properties of the Comprehensive Measure of Meaning. The Journal of Positive Psychology

Koga, H.K., Grodstein, F., Williams, D.R., Buchman, A.S., and Kubzansky, L.D. (2024). Purpose in life and its association to ParkinsonismThe Journals of Gerontology: Series B

Chen, J. et al. (2025). It takes a village: Social engagement with family is associated with reduction in postpartum depression during psychotherapy

Hikichi, H., Kondo, K., & Kawachi, I. (2024). Associations between community social capital and posttraumatic growth among older survivors 11 years after a natural disaster. American Journal of Epidemiology

Hsu, Y., Grodstein, F., Liu, T., Chang, C., Kawachi, I., & Chen, J. T. (2025). Causal mediation of the association between educational attainment and late-life cognitive function by trajectories of social participation. Social Science & Medicine, 370, 117861

Huffman, J., (2024). A peer support intervention in patients with hematologic malignancies undergoing hematopoietic stem cell transplantation (HSCT): The STEPP randomized pilot trial design and methods. Contemporary Clinical Trials, 148

Kim, E.S., et al. (2024). A national cohort study of community belonging and its influence on premature mortality. Journal of Epidemiology & Health

Koenen, K., et al. (2025). The relationship between social adversity, micro-RNA expression and post-traumatic stress in a prospective, community-based cohort

Viswanath, K., et al. (2025). Improving Mental Health Among Indian Adolescents: Evidence From an Innovative Adolescent Peer-Led Intervention in Rajasthan, India.  Journal of Adolescent Health, 76(3)

Williams, D. R., et al. (2025). The role of religiosity and spirituality in coping with sickle cell disease clinical severity. Journal of Sickle Cell Disease, 2(1)

Koenen, K.C., Denckla, C.M., et al. (2025). Multi-level socioeconomic modifiers of the comorbidity of post-traumatic stress and tobacco, alcohol, and cannabis use: the importance of income.   Social Psychiatry and Psychiatric Epidemiology

Liu, Y., & Marciano, L. (2024). Appnome analysis reveals small or no associations between social media app-specific usage and adolescent well-being. Scientific Reports, 14 (30836)

Marciano, L., Dubicka, B., Magis-Weinberg, L., Morese, R., Viswanath, K., & Weber, R. (2024). Digital Media, Cognition, and Brain Development in Adolescence. In D. A. Christakis, L. Hale (eds.), Handbook of Children and Screens, (21-29). Springer

Marciano, L., et al. (2024). User-Donated Screenshots Analysis: Feasibility of a New Approach to Collect Objective Social Media App Usage in Adolescents. In: Thomson, R., et al. Social, Cultural, and Behavioral Modeling,14972, 80-89. Springer

Marciano, L., Jindal, S., & Viswanath, K. (2024). Digital Detox and Well-Being. Pediatrics, 154 (4)

Marciano, L., et al. (2024). Safeguarding young users on social media through academic oversight. Nature Reviews Psychology

Mendez, S., Munoz-Najar, S., Emmons, K., & Viswanath, K. (2024). Journal of Medical Internet Research – US State Public Health Agencies’ Use of Twitter From 2012 to 2022: Observational Study. Journal of Medical Internet Research, 27

Long, K., Wilkinson, R., Cowden, R.G., Chen, Y., and VanderWeele, T.J. (2024). Hope in adolescence and subsequent health and well-being in adulthood: An outcome-wide longitudinal studySocial Science & Medicine, 347

Park, E.R., et al. (2025). Development of the bi-directional engagement strategy tool (BEST) to assist implementation of wellness programs in federally qualified health centers. Crisis, Stress, and Human Resilience: An International Journal, 6(3)

Wang, K., Goldenberg, A., Lerner, J. S., & Gross, J. J. (2025). Enhancing workplace well-being through reappraisal in a nationwide field experiment

Wu, C., & Kawachi, I. (2024). A triple trust penalty? The majority-minority gap in subjective wellbeing. Social Science & Medicine