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The Center for Communicable Disease Dynamics works to improve methods for infectious disease modeling and statistical analysis, quantify disease and intervention impact, engage with policymakers to enhance decision-making, and train the next generation of scientists.

Email ccdd@hsph.harvard.edu

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Location

677 Huntington Avenue
Kresge Building, Suite 506
Boston, MA 02115

Publications

Below is a list of the Center’s most recent publications. For a comprehensive list of each faculty member’s work, please visit their individual Catalyst profiles linked below.

Marc Lipsitch

Director of CCDD; Professor of Epidemiology

Bill Hanage

Assoc. Director of CCDD; Professor of Epidemiology

Caroline Buckee

Professor of Epidemiology

Yonatan Grad

Professor of Immunology and Infectious Diseases

Jeff Imai-Eaton

Associate Professor of Epidemiology

Nicolas Alan Menzies

Associate Professor of Global Health

Megan Murray

Professor in the Department of Epidemiology

Mauricio Santillana

Adjunct Professor of Epidemiology

Publications

Browse recent publications from the Center.

How Should We Study the Indirect Effects of Antimicrobial Treatment Strategies?: A Causal Perspective.

Authors: Gago J, Boyer C, Lipsitch M Journal: Epidemiology (Cambridge, Mass.) Publish Date: 2025 Oct 28 Pages: DOI: doi: 10.1097/EDE.0000000000001921 PMID: 41176807

Effective antimicrobial stewardship requires unbiased assessment of the benefits and harms of different treatment strategies, considering both immediate patient outcomes…
HIV incidence and prevalence among adults in Mozambique: estimates from the Population-based HIV Impact Assessment Survey (INSIDA 2021) and district-level modelling.

Authors: Gudo ES, McCabe KC, Fazito E, Catano D, Tiberi O, Boothe M, McOwen J, Imai-Eaton JW, Stevens O, Manembe L, El-Sadr WM Journal: Journal of the International AIDS Society Publish Date: 2025 Nov Pages: :e70008 DOI: doi: 10.1002/jia2.70008 PMID: 41152562

Accurate information is needed to prioritize programmes and resources that address gaps in the HIV response. We examined findings from…
Reproductive stage and other risk factors associated with intimate partner violence: a multi-site study of women living with HIV in the United States.

Authors: Kuchukhidze S, Kacanek D, Brummel SS, Davtyan M, Lee J, Patel K, Rönn MM, Steinberg JR, Williams PL, Yee LM, Imai-Eaton JW, Powis K, HOPE study team Journal: AIDS (London, England) Publish Date: 2025 Oct 27 Pages: DOI: doi: 10.1097/QAD.0000000000004392 PMID: 41143749

The 2025 US National HIV/AIDS Strategy identifies intimate partner violence (IPV) as a key social determinant in the HIV response….
National- and state-level SARS-CoV-2 immunity trends from January 2020 to December 2023: a mathematical modeling analysis.

Authors: Klaassen F, Swartwood NA, Chitwood MH, Lopes R, Haraguchi M, Salomon JA, Cohen T, Menzies NA Journal: The Journal of infectious diseases Publish Date: 2025 Oct 23 Pages: DOI: doi: 10.1093/infdis/jiaf532 PMID: 41129530

Effective immune protection against SARS-CoV-2 infection and severe COVID-19 disease continues to change due to viral evolution and waning immunity….
Changes in child mortality and population health following 10 years of health systems strengthening in rural Madagascar: A longitudinal cohort study.

Authors: Garchitorena A, Miller AC, Razanadranaivo HL, Rakotonirina L, Barriault SA, Razafinjato B, Kotchofa JA, Rafenoarimalala F, Rakotonanahary RJL, Ihantamalala FA, Evans MV, Tolojananahary AT, Ramanandraitsiory V, Tsitinomen'nyaina A, Ralaivavikoa FA, Raza-Fanomezanjanahary EM, Randriamanambintsoa M, Andrianambinina S, Yasmine LL, Murray MB, Rich ML, Cordier LF, Finnegan KE, Bonds MH, Randriamanantany ZA Journal: PLoS medicine Publish Date: 2025 Oct Pages: :e1004549 DOI: doi: 10.1371/journal.pmed.1004549 PMID: 41056272

Reducing child mortality rates is a unifying goal of the global health and international development communities. In Africa, unambiguous empirical…
Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance.

Authors: Culviner PH, Frey AM, Liu Q, Ha DTM, Thai PVK, Thu DDA, Quang NL, Calderon R, Lecca L, Caws M, Dunstan SJ, Murray MB, Thuong NTT, Fortune SM Journal: Cell Publish Date: 2025 Sep 30 Pages: DOI: doi: 10.1016/j.cell.2025.09.005 PMID: 41033311

Mycobacterium tuberculosis (Mtb) has co-evolved with humans for thousands of years and is characterized by variation in virulence, transmissibility, and…
Strategies to Improve PrEP Adherence in People Who Use Drugs: A Systematic Review.

Authors: Briggs J, Chiosi J, Papineni S, Murray M Journal: AIDS and behavior Publish Date: 2025 Sep 29 Pages: DOI: doi: 10.1007/s10461-025-04876-8 PMID: 41016995

People who use drugs (PWUD) face a disproportionately high risk of HIV, accounting for a considerable share of cases in…
Equity considerations in COVID-19 vaccine allocation modelling: a methodological study.

Authors: Rumpler E, Lipsitch M Journal: Interface focus Publish Date: 2025 Sep 26 Pages: :20240037 DOI: doi: 10.1098/rsfs.2024.0037 PMID: 41017906

We conducted a methodological study of COVID-19 vaccine allocation modelling papers, specifically looking for publications that considered equity. We found…
Insurance Dynamics During Childhood in the Fragmented US Health System.

Authors: Shen Y, Sommers BD, Hatfield LA, Hayes C, Pandya A, Menzies NA Journal: JAMA Publish Date: 2025 Sep 24 Pages: DOI: doi: 10.1001/jama.2025.15488 Publication Status: Online ahead of print PMID: 40991296

US children’s health insurance is fragmented across public and private sources, with wide state variation. However, the extent of children’s…
The Role of Youths in Within-Household Tuberculosis Transmission: A Household Contact Cohort Study.

Authors: Brooks MB, Lecca L, Becerra MC, Calderon RI, Contreras CC, Jimenez J, Yataco RM, Zhang Z, Murray MB, Huang CC Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Publish Date: 2025 Sep 24 Pages: DOI: doi: 10.1093/cid/ciaf490 Publication Status: Online ahead of print PMID: 40990486

Youth aged 15-24 years are significantly impacted by tuberculosis globally. Their expanding social networks heighten exposure risks, potentially amplifying tuberculosis…

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