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Fine-Mapping Causal Tissues and Genes at Disease-Associated Loci

Virtual

Abstract: Complex diseases often have distinct mechanisms spanning multiple tissues. We propose Tissue-Gene Fine-Mapping (TGFM), which infers the posterior probability (PIP) for each gene-tissue pair to mediate a disease locus by analyzing summary statistics and eQTL data; TGFM also assigns PIPs to non-mediated variants. TGFM accounts for co-regulation across genes and tissues and models uncertainty...

Helping Hands: The Mississippi Delta Food Community

Kresge G2, Harvard Chan School 677 Huntington Ave., Boston, MA

Join us for a preview of the documentary Helping Hands followed by a conversation with the filmmaker Jack Thomas Spears on the resilience of the Mississippi Delta’s food community and how neighbors...

ⓘ Harvard Chan School hosts a diverse array of speakers, invited to share both scholarly research and personal perspectives. They do not speak for the School, and hosting them does not imply endorsement of their views, organizations, or employers.