Sarah Fortune
John LaPorte Given Professor of Immunology and Infectious Diseases
Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health
Departments
Department of Immunology and Infectious Diseases
Other Positions
Chair, Department of Immunology and Infectious Diseases
Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health
Related Links
Biography
My laboratory focuses on the molecular basis of population heterogeneity in Mycobacterium tuberculosis (Mtb) and the extent to which differences between mycobacterial cells contribute to differences in disease and treatment outcomes. Our work combines bacterial genetic approaches with high throughput methodologies including population genomics, ssRNAseq and quantitative live cell imaging to define the molecular mechanisms by which Mtb generates diversity and how this diversity enables the bacterium to survive subsequent selective forces including antibiotics and immune selection. We further seek to understand the impact of host immune responses on the interaction of Mtb with the infected host, again working at both single cell and genomic levels. My work engages a broad network of collaborators including experts in technologies to assess single cell behavior at MIT and MGH, experts in sequencing methodologies at the Broad Institute and experts in human immunology at the Ragon Institute, where I am the outgoing Director of the TB Program.
Education and Training
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B.S., Biology
Yale University -
M.D., Medicine
Columbia University, College of Physicians and Surgeons -
, 3years Internship/Residency in Internal Medicine
Brigham and Women’s Hospital -
, 1year Clinical Fellowship in Infectious Diseases
Brigham and Women’s Hospital -
Post Doc, Immunology & Infectious Diseases - 5years Postdoctoral Fellow
HSPH
Awards and Honors
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Junior Faculty Mentoring Award, 2019 - 2020
Harvard School of Public Health -
John LaPorte Given Professor , 2017
Harvard School of Public Health -
Alice B. Hamilton Award, 2013
Harvard School of Public Health -
Investigator in the Pathogenesis of Infectious Diseases, 2012
Burroughs Welcome Foundation -
Melvin and Geraldine Glimcher Associate Professorship, 2012
Harvard School of Public Health -
Science and Public Leadership Fellow, 2010
PopTech -
Clinical Scientist Development Award, 2010
Doris Duke -
Early Career Award, 2007
Hood Foundation -
Early Career Award, 2007
Howard Hughes Medical Institute -
New Innovator Award, 2007
National Institute of Health -
The Maxwell Finland Award for Excellence in Research, 2004
Mass. Infectious Disease Society -
The Maxwell Finland Award for Excellence in Research, Mass. Infectious Disease Society, 2004
The National Foundation for Infectious Diseases -
Teaching Award for Residents in Internal Medicine, 2001
Harvard Medical School - Alpha Omega Alpha, 1996
- Phi Beta Kappa, 1993
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Medical Student Fellowship for Return to Medical Studies, 1993
Howard Hughes Medical Institute -
Medical Student Research Fellowship, 1993
Howard Hughes Medical Institute -
B.S. Summa Cum Laude, 1990
Yale -
Community Service Award, 1989
Yale
