Park Lab
Research at the Park Lab is focused on understanding the role of the airway epithelium in the lung. As the primary barrier against external stimuli—ranging from environmental pollutants and allergens to bacteria and viruses—the airway epithelium serves as the first line of defense for respiratory health.
665 Huntington Avenue
Building 1, Room 306
Boston, MA 02115
Research Team
Dr. Faria Khan is an air pollution toxicologist. Her research focuses on the toxicity of chemicals of emerging concern (CECs), with a specific focus on their involvement in the development and progression of cancer in airway epithelial cells. This research delves into the molecular mechanisms underlying cellular plasticity caused by these CECs. The findings from this study have the potential to shape public health policy decisions.
Dr. Megan Solan is an environmental toxicologist. Her research focuses on the mechanisms of cellular plasticity that are induced by per- and polyfluoroalkyl substances (PFAS) and polycyclic aromatic hydrocarbons (PAHs) in human airway epithelial cells. Understanding how environmental exposures affect mechanisms of cellular plasticity can offer vital insights into disease pathogenesis and contribute to public health improvement.
Dr. Hyo Jin Kim is a food scientist and immunologist. Her research focuses on elucidating the signaling pathways and damage responses in airway epithelial cells caused by exposure to environmental pollutants and underlying disease conditions, such as asthma. By investigating the mechanisms of epithelial cell damage and repair, her goal is to develop strategies that mitigate the adverse effects of environmental pollutants on respiratory health, ultimately contributing to improved public health outcomes.
Dr. Chim Mwase is an airway epithelial cell biologist. Her research focuses on the role of tissue factor proteins contained in extracellular vesicles released by mechanically compressed airway epithelial cells. Mechanical compression mimics the mechanical effect of the airway epithelium in the narrowed airway during asthma exacerbations. Thus, her goal is to identify the role of tissue factor protein in asthma pathogenesis.
Team Photos
Alumni
Postdoctoral Fellows
- Chimwemwe Mwase, PhD
Research Fellow: May 2023 – May 2024 - Hyangsu Nam, PhD
Research Fellow: August 2023 – June 2024,
Current position: BIDMC - Thien-Khoi (TK) Phung, PhD
Research Fellow: March 2020 – Oct 2022
Current position: Novartis Institutes for Biomedical Research - Antonella Marrocco, MD, PhD
Research Fellow: July 2021 – Aug 2022 - Alane Blythe Dy, PhD
Research Fellow; Oct 2020 – June 2022 - Jennifer Mitchel, PhD
Research Fellow, Research Associate, Research Scientist; June 2013 – Dec 2021
Current position: Assistant Professor of Biology, Wesleyan University - Michael O’Sullivan, PhD
Research Fellow; Sept 2016 – June 2021
Current position: Principal Scientist at the Novartis Institutes for Biomedical Research - Tiziana Patrizia Cremona, PhD
Research Fellow: Aug 2017 – June 2019 - Tiffany Tan, PhD
Research Fellow: June 2017 – Dec 2018 - Sae-Hoon Kim, MD, PhD
Research Fellow: 2014- 2015
Current position: Associate professor, Seoul National University Bundang Hospital, South Korea
PhD Students
- Chimwemwe Mwse [Spring 2019 – April 2023]
- Gabrielle Webb [Spring 2020- April 2023]
SM Students
- Emma Goetzinger [March 2023 – May 2024]
Undergraduate Student Interns
- Ji Won Baek
Undergraduate intern, Northeastern University); June 2018 – Dec 2018 - David Stevenson
Summer intern, Vassar College, Summer 2018 - Rebecca Hirsch
Undergraduate intern, Northeastern University, Fall 2016
Current: PhD Student at the Univ. of North Carolina - Maureen McGill, MD
Undergraduate intern, Northeastern University; Fall 2013, Fall 2014
Current: Medical Intern at NYC hospital