Harvard Chan Bioinformatics Core
The Harvard Chan Bioinformatics Core in the Department of Biostatistics provides a single point of contact for Harvard researchers seeking bioinformatics analysis services, training and platform development. Specializing in applications of high-throughput sequencing analysis, core staff aid researchers with the management, integration, and contextual analysis of biological data, supporting the advancement of research and ultimately, aiming to improve human health.
401 Park Drive
Level 3 East
Boston, MA 02215
Who We Are
The Harvard Chan Bioinformatics Core (HBC) is a dedicated team of bioinformaticians and computational biologists passionate about empowering biomedical research. Serving the Harvard T.H. Chan School of Public Health and the broader Boston community, we provide expertise in the analysis, interpretation, and visualization of high-throughput genomics data. Our collaborative approach integrates advanced computational methods, robust workflows, and extensive training resources to support researchers at every stage – from experimental design to insightful data interpretation. We strive to deliver high-quality, reproducible results and foster a culture of collaboration, innovation, and open science.
What We Do
The HCBC offers bioinformatics consulting and analysis services across the Harvard community, providing expertise in variant analysis, bulk and single cell transcriptomics and epigenomics, multimodal data integration, and spatial profiling. We work with researchers throughout the research life cycle of a project, including supporting grants, advising on experimental design, analyzing data from raw data through to figure generation and publication, and assisting with data management.
Training is key to HCBC’s mission of building bioinformatics capacity across Harvard and empowering researchers to analyze their own data. Our training team holds regular hands-on workshops focused on basic data skills and analysis of high throughput sequencing data, with an emphasis on experimental design, current best practices, and reproducibility. Click here to learn more.
Our Platforms leverage nf-core community best-practice pipelines and standardized workflows, enabling us to deliver high-quality, reproducible analyses at scale. In addition to integrating trusted community standards and developing custom Nextflow solutions, we’ve created bcbioR – an open-source package designed to establish guidelines for sequencing data interpretation based on HCBC’s expertise and our community of contributors. This commitment to standardized, best-practice workflows ensures consistent, robust results for every project. Click here to learn more.
Funders
HBC’s training program is funded by Harvard Medical School and Dana Farber/Harvard Cancer Center.
Bioinformatics planning and support for writing bioinformatics components of grants is supported by Harvard Catalyst.