Kristopher Sarosiek

Associate Professor of Radiation Biology and Cell Death

Environmental Health, Harvard T.H. Chan School of Public Health

Departments

Department of Environmental Health

Other Positions

Acting Co-Director, John B. Little Center for Radiation Sciences

Environmental Health, Harvard T.H. Chan School of Public Health

Biography

Inflammation and mitophagy are mitochondrial checkpoints to aging.

Guilbaud E, Sarosiek KA, Galluzzi L. Nat Commun 2024 Apr 20
Functional genomic screens with death rate analyses reveal mechanisms of drug action.

Honeywell ME, Isidor MS, Harper NW, Fontana RE, Birdsall GA, Cruz-Gordillo P, Porto SA, Jerome M, Fraser CS, Sarosiek KA, Guertin DA, Spinelli JB, Lee MJ. Nat Chem Biol 2024
Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma.

Matoba Y, Zarrella DT, Pooladanda V, Azimi Mohammadabadi M, Kim E, Kumar S, Xu M, Qin X, Ray LJ, Devins KM, Kumar R, Kononenko A, Eisenhauer E, Veillard IE, Yamagami W, Hill SJ, Sarosiek KA, Yeku OO, Spriggs DR, Rueda BR. Br J Cancer 2024
In situ architecture of Opa1-dependent mitochondrial cristae remodeling.

Fry MY, Navarro PP, Hakim P, Ananda VY, Qin X, Landoni JC, Rath S, Inde Z, Lugo CM, Luce BE, Ge Y, McDonald JL, Ali I, Ha LL, Kleinstiver BP, Chan DC, Sarosiek KA, Chao LH. EMBO J 2024
Pulsed ultrasound promotes secretion of anti-inflammatory extracellular vesicles from skeletal myotubes via elevation of intracellular calcium level.

Yamaguchi A, Maeshige N, Noguchi H, Yan J, Ma X, Uemura M, Su D, Kondo H, Sarosiek K, Fujino H. Elife 2023 Dec 06