Program in Quantitative Genomics
The Program in Quantitative Genomics (PQG) develops and applies quantitative methods to help handle massive genetic, genomic, and health data. Based in the Harvard Chan School and Longwood Medical Area, its goal is to improve health through the interdisciplinary study of genetics, behavior, environment, and health.
255 Huntington Ave
Building 2, 4th floor
Boston, MA 02115
Computational Pathology at Scale: From Discovery to Drug Development to Global Diagnostics
Computational pathology now serves three distinct users: the scientist mining tissue for biology, the drug developer running trials across hundreds of sites, and the pathologist signing out a case in clinical practice. Each demands a different solution. Discovery favors automation and breadth: quantitative morphology extracted across indications and fused at scale with genomic, clinical, and other high-dimensional data. Drug development adds regulatory rigor and a platform that can support the operations of a global clinical trial, from site onboarding to locked data. Clinical diagnostics requires deep integration into the pathologist’s workflow and the operations of the anatomic pathology laboratory. This talk draws on a decade of building products in all three settings to show what one modeling foundation can share, where each setting forces its own design, what it takes to move from a research pipeline to AI running in laboratories worldwide, and how a shared digital infrastructure delivers long-term benefits to discovery and clinical practice alike.