Quantitative Biomedical Research Center
The Quantitative Biomedical Research Center (QBRC) at the Harvard T.H. Chan School of Public Health under the Department of Biostatistics supports the biomedical research community. QBRC provides large scale biomedical data mining, management, pattern recognition, and research software engineering (RSE) support to scientists in the Harvard research community and beyond.
677 Huntington Ave.
Building 2, Room 410
Boston, MA 02115
Data Mining
Pattern Classification
We offer highly customized data mining services using machine learning tools such as regression models, unsupervised clustering methods, and supervised learning methods. These type of projects include but not limited to:
- Population subtype discovery
- Biomarker discovery
- Predictive model construction
Multi-Data Type Integration
Technology advancements have made it cost-effective to collect diverse types of high dimensional data. We offer network-based computational methods to combine multiple data types, such as clinical, questionnaires, image, and genomic data, for a set of samples to perform pattern recognition and model interactions.
- Identify sample similarity and community from multi-type data measurements
- Assess level of interaction between driver and respondents (i.e. gene expression driven by transcription factor binding)
- Isolate single sample contribution to network
Image Analysis using Deep Learning
Complex deep convolutional neural networks (CNNs), which are able “automatically” to capture predictive features in image data once appropriately trained, have garnered significant attention for their potential utility in biomedical applications with its accuracy. We provide deep learning neural network model construction service for quantitative image analysis. Applications include classification and regression modeling, as well as deep feature embedding for image data such as microscopy and histopathology.