Our lab focuses on System Serology, a comprehensive approach to studying humoral immunity. We analyze antibody responses to infectious diseases using high-throughput functional assays and biophysical profiling techniques. We integrate wet lab immunology with computational modeling and machine learning to uncover the antibody signatures linked to disease outcome, allergy sensitivity, or as a biomarker for health status. We are particularly interested in how the immune system moves over time, and how we can incorporate models of immune temporal fluidity into next generation vaccine approaches, immune therapies, and allergy desensitivity.