Publications

Selected Publication (# advisee, ^ first/co-first author, * senior/co-senior/corresponding author）

Cao T#, Zhao J#, Hong X, Wang G, Pearson C, Adams WG, Hu FB, Wang X, Liang L.* (2023) Cord Blood Plasma Metabolome-wide Associations With Height From Birth to Adolescence. J Bone Miner Res. 2023 May;38(5):707-718. doi: 10.1002/jbmr.4790. Epub 2023 Mar 8. PMID: 36805685

Hu J#, Xu X, Li J, Jiang Y, Hong X, Rexrode KM, Wang G, Hu FB, Zhang H, Karmaus WJ, Wang X, Liang L.* (2023) Sex differences in the intergenerational link between maternal and neonatal whole blood DNA methylation: a genome-wide analysis in 2 birth cohorts. Clin Epigenetics. 2023 Mar 25;15(1):51. doi: 10.1186/s13148-023-01442-8. PMID: 36966332

Meir AY#, Huang W, Cao T, Hong X, Wang G, Pearson C, Adams WG, Wang X, Liang L*. (2023) Umbilical cord DNA methylation is associated with body mass index trajectories from birth to adolescence. EBioMedicine. 2023 May;91:104550. doi: 10.1016/j.ebiom.2023.104550. Epub 2023 Apr 21. PMID: 37088033

Han X#, Lains I, Li J#, Li J#, Chen Y, Yu B, Qi Q, Boerwinkle E, Kaplan R, Thyagarajan B, Daviglus M, Joslin CE, Cai J, Guasch-Ferré M, Tobias DK, Rimm E, Ascherio A, Costenbader K, Karlson E, Mucci L, Eliassen AH, Zeleznik O, Miller J, Vavvas DG, Kim IK, Silva R, Miller J, Hu F, Willett W, Lasky-Su J, Kraft P, Richards JB, MacGregor S, Husain D, Liang L.* (2023) Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration. Cell Rep Med. 2023 Jul 18;4(7):101085. doi: 10.1016/j.xcrm.2023.101085. Epub 2023 Jun 21. PMID: 37348500

Si J#, Meir AY#, Hong X, Wang G, Huang W, Pearson C, Adams WG, Wang X, Liang L.* (2023) Maternal pre-pregnancy BMI, offspring epigenome-wide DNA methylation, and childhood obesity: findings from the Boston Birth Cohort. BMC Med. 2023 Aug 23;21(1):317. doi: 10.1186/s12916-023-03003-5. PMID: 37612641

Zhu Z, Li Y, Freishtat RJ, Celedón JC, Espinola JA, Harmon B, Hahn A, Camargo CA Jr, Liang L*, Hasegawa K*. (2023) Epigenome-wide association analysis of infant bronchiolitis severity: a multicenter prospective cohort study. Nat Commun. 2023 Sep 7;14(1):5495. doi: 10.1038/s41467-023-41300-y. PMID: 37679381

Wang F, Tessier AJ, Liang L, Wittenbecher C, Haslam DE, Fernández-Duval G, Heather Eliassen A, Rexrode KM, Tobias DK, Li J, Zeleznik O, Grodstein F, Martínez-González MA, Salas-Salvadó J, Clish C, Lee KH, Sun Q, Stampfer MJ, Hu FB, Guasch-Ferré M. (2023) Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals. Nat Commun. 2023 Sep 16;14(1):5744. doi: 10.1038/s41467-023-41515-z. PMID: 37717037

Yaskolka Meir A#, Keller M, Hoffmann A, Rinott E, Tsaban G, Kaplan A, Zelicha H, Hagemann T, Ceglarek U, Isermann B, Shelef I, Blüher M, Stumvoll M, Li J, Haange SB, Engelmann B, Rolle-Kampczyk U, von Bergen M, Hu FB, Stampfer MJ, Kovacs P, Liang L*, Shai I*. (2023) The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial. BMC Med. 2023 Sep 25;21(1):364. doi: 10.1186/s12916-023-03067-3. PMID: 37743489

Huang W, Meir AY#, Olapeju B, Wang G, Hong X, Venkataramani M, Cheng TL, Igusa T, Liang L*, Wang X*. (2023) Defining longitudinal trajectory of body mass index percentile and predicting childhood obesity: methodologies and findings in the Boston Birth Cohort. Precis Nutr. 2023 Apr 21;2(2):e00037. doi: 10.1097/PN9.0000000000000037. eCollection 2023 Jun. PMID: 37745028

Yaskolka Meir A#, Yun H#, Stampfer MJ, Liang L, Hu FB. (2023) Nutrition, DNA methylation and obesity across life stages and generations. Epigenomics. 2023 Oct;15(19):991-1015. doi: 10.2217/epi-2023-0172. Epub 2023 Nov 7. PMID: 37933548

Guo Y#, Chung W#, Shan Z, Zhu Z, Costenbader KH, Liang L*. (2023) Genome-Wide Assessment of Shared Genetic Architecture Between Rheumatoid Arthritis and Cardiovascular Diseases. J Am Heart Assoc. 2023 Nov 10;12(22):e030211. doi: 10.1161/JAHA.123.030211. Online ahead of print. PMID: 37947095

Han X#, Zhu Z#, Xiao Q#, Li J#, Hong X, Wang X, Hasegawa K,Camargo CA, Liang L*. (2022) Unique genetic architecture shared between childhood body mass index and childhood asthma linking to underlying obesity-related biomarkers. Communications Biology. 2022 Oct 17;5(1):1098. PMID: 36253437

Han X#, Liang L*. (2022) metabolomicsR: a streamlined workflow to analyze metabolomic data in R. Bioinformatics Advances. 2022, 1–3 (Package, Tutorial)

Lin Y#, Ma B#, Yang Y#, Chen Y#, Huang J, Li W, Yu X, Liang L*. (2022) Impaired kidney function biomarkers and risk of severe COVID-19: Analysis of population-based cohort data. Mol Genet Genomic Med. 2022 Sep 20:e2047. doi: 10.1002/mgg3.2047. Online ahead of print. PMID: 36124564

Yaskolka Meir A#, Liang L*. (2022) The gut microbiota’s role in diet-related cardiovascular health – an innocent bystander or a key mediator; the question remains. Eur J Prev Cardiol.2022 Aug 5:167. doi: 10.1093/eurjpc/zwac167. Online ahead of print. PMID: 35929653

Zhu Z#, Li J, Si J#, Ma B#, Shi H, Lv J, Cao W, Guo Y, Millwood I, Walters R, Lin K, Yang L, Chen Y, Du H, Yu B, Hasegawa K, Camargo CA, Moffatt MF, Cookson WOC, Chen J, Chen Z, Li L, Yu C*, Liang L*. (2021) A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. European Respiratory Journal 58(4):2100199.

Si J#, Li J, Yu C, Guo Y, Bian Z, Millwood IY, Yang L, Walters RG, Chen Y, Du H, Yin L, Chen J, Chen J, Chen Z, Li L*, Liang L*, Lv J*; on behalf of the China Kadoorie Biobank Collaborative Group (2021) Improved lipidomic profile mediates the effects of adherence to healthy lifestyles on coronary heart disease. eLife 10:e60999. PMID: 33558007

Feng YA#, Guo Y#, Pain L, Lathrop GM, Laprise C, Moffatt MF, Cookson WOCM, Liang L*(2020) Estimating cell-type specific DNA methylation effects in heterogeneous cellular populations. Epigenomics PMID: 33350870

Zhu Z#, Hasegawa K, Ma B, Fujiogi M, Camargo CA Jr, Liang L*. (2020) Association of obesity and its genetic predisposition with the risk of severe COVID-19: Analysis of population-based cohort data. Metabolism. 2020 Aug 22;112:154345. PMID: 32835759 PMCID: PMC7442576

Zhu Z#, Hasegawa K, Ma B, Fujiogi M, Camargo CA Jr, Liang L*. (2020) Association of asthma and its genetic predisposition with the risk of severe COVID-19. J Allergy Clin Immunol. 2020 Aug;146(2):327-329.e4. PMID: 32522462 PMCID: PMC7423602

Lin Y#, Yin P, Zhu Z#, Peng Y, Li M, Li J, Liang L*, Yu X* (2020) Epigenome-wide Association Study and Network Analysis for IgA Nephropathy from CD19 + B-cell in Chinese Population. Epigenetics PMID: 33319642

Zhu Z#, Hasegawa K, Camargo CA Jr, Liang L. (2020) Investigating asthma heterogeneity through shared and distinct genetics: Insights from genome-wide cross-trait analysis. Journal of Allergy and Clinical Immunology. 2020 Jul 18:S0091-6749(20)30966-0. PMID: 32693092 PMCID: PMC7368660

Li J#, Guasch-Ferré M, Chung W#, Ruiz-Canela M, Toledo E, Corella D, Bhupathiraju SN, Tobias DK, Tabung FK, Hu J#, Zhao T#, Turman C, Feng YA#, Clish CB, Mucci L, Eliassen AH, Costenbader KH, Karlson EW, Wolpin BM, Ascherio A, Rimm EB, Manson JE, Qi L, Martínez-González MÁ, Salas-Salvadó J, Hu FB*, Liang L*. (2020) The Mediterranean diet, plasma metabolome, and cardiovascular disease risk. Eur Heart J. 2020 May 14:ehaa209. doi: 10.1093/eurheartj/ehaa209. Online ahead of print.PMID: 32406924
Editorial at the same issue introducing our study is available at PMID: 32357245.

Zhu Z#, Guo Y#, Shi H, Liu CL, Panganiban RA, Chung W#, O’Connor LJ, Himes BE, Gazal S, Hasegawa K, Camargo CA, Jr., Qi L, Moffatt MF, Hu FB, Lu Q, Cookson WOC, Liang L*. (2020) Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank. J Allergy Clin Immunol. 145(2):537-549. PMC7010560.

Guo Y#, Chung W#, Zhu Z#, Shan Z, Li J#, Liu S, Liang L*. (2019) Genome-Wide Assessment for Resting Heart Rate and Shared Genetics With Cardiometabolic Traits and Type 2 Diabetes. J Am Coll Cardiol. 74(17):2162-2174. PMID: 31648709.
Editorial: Munroe et al J Am Coll Cardiol. 2019

Huan T, Joehanes R, Song C, Peng F, Guo Y#, Mendelson M, Yao C, Liu C, Ma J, Richard M, Agha G, Guan W, Almli LM, Conneely KN, Keefe J, Hwang SJ, Johnson AD, Fornage M, Liang L*, Levy D*. (2019) Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease. Nature Communications. 10(1):4267. PMC6753136.

Wang G^, Sun Q^, Liang L^, Clash C, Zhang C, Hong X, Ji Y, Radovick S, Pearson C, Bartell TR, Zuckerman B, Cheng TL, Hu FB, Wang X. (2019) Inter-generational link of obesity in term and preterm births: role of maternal plasma acylcarnitines. Int J Obes (Lond). 43(10):1967-1977. PMID: 31332276.

Zhu Z#, Lin Y#, Li X, Driver JA, Liang L*. (2019) Shared genetic architecture between metabolic traits and Alzheimer’s disease: a large-scale genome-wide cross-trait analysis. Hum Genet. 2019 Feb 25. doi: 10.1007/s00439-019-01988-9.

Chung W#, Chen J#, Turman C, Lindstrom S, Zhu Z#, Loh PR, Kraft P, Liang L*. (2019) Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes. Nat Commun. 2019 Feb 4;10(1):569.

Chaffin MD#, Cao L#, Deik AA, Clish CB, Hu FB, Martínez-González MA, Razquin C, Bullo M, Corella D, Gómez-Gracia E, Fiol M, Estruch R, Lapetra J, Fitó M, Arós F, Serra-Majem L, Ros E, Liang L.* (2019) MetProc: separating measurement artifacts from true metabolites in an untargeted metabolomics experiment. J Proteome Res. 2018 Dec 18. doi: 10.1021/acs.jproteome.8b00893.

Zhu Z#, Zhu X, Liu CL, Shi H, Shen S, Yang Y, Hasegawa K, Camargo CA, Jr., Liang L*. (2019) Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. Eur Respir J. 54(6):PMID: 31619474.

Ma B#, Allard C, Bouchard L, Perron P, Mittleman MA, Hivert MF, Liang L*. (2019) Locus-specific DNA methylation prediction in cord blood and placenta. Epigenetics. 14(4):405-420. PMC6557556.

Li J#, Zhu X, Yu K, Jiang H, Zhang Y, Wang B, Liu X, Deng S, Hu J, Deng Q, Sun H, Guo H, Zhang X, Chen W, Yuan J, He M, Bai Y, Han X, Liu B, Liu C, Guo Y, Zhang B, Zhang Z, Hu F, Gao W, Li L, Lathrop M, Laprise C, Liang L*, Wu T* (2018) Exposure to polycyclic aromatic hydrocarbons and accelerated DNA methylation aging. Environmental Health Perspectives126(6):067005.

Zhu Z#, Lee PH, Chaffin MD, Chung W, Loh PR, Lu Q, Christiani DC, Liang L*. (2018) A genome-wide cross trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. Nature Genetics 50(6):857-864.

Li J#, Zhu X, Yu K, Jiang H, Zhang Y, Deng S, Cheng L, Liu X, Zhong J, Zhang X, He M, Chen W, Yuan J, Gao M, Bai Y, Han X, Liu B, Luo X, Mei W, He X, Sun S, other authors, Mao X, Peng Y, Mao Y, Ye P, Wang QK, Qi L, Hu F, Liang L*, Wu T*. (2017) Genome-Wide Analysis of DNA Methylation and Acute Coronary Syndrome. Circulation Research. CIRCRESAHA.116.310324

Feng YA#, Cho K, Lindstrom S, Kraft P, Cormack J; IGAP Consortium, Colorectal Transdisciplinary Study (CORECT); Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE); Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE); Transdisciplinary Research in Cancer of the Lung (TRICL), Liang L*, Driver JA. (2017) Investigating the genetic relationship between Alzheimer’s disease and cancer using GWAS summary statistics. Hum Genet. 136(10):1341-1351.

Chen J#, Behnam E, Huang J, Moffatt MF, Schaid DJ, Liang L*, Lin X*. (2017) Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA. BMC Genomics. 18(1):413.

Mendelson MM*, Marioni RE*, Joehanes R, Liu C, Hedman AK, Aslibekyan S, Demerath EW, other authors, Liang L*, Levy D*, Deary IJ* (2016) Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach PLoS Medicine 14(1):e1002215.

Sun L*, Liang L*, Gao X, Zhang H, Yao P, Hu Y, Ma Y, Wang F, Jin Q, Li H, Li R, Liu Y, Hu FB, Zeng R, Lin X, Wu J. (2016) Early Prediction of Developing Type 2 Diabetes by Plasma Acylcarnitines: A Population-Based Study. Diabetes Care. 2016 Sep;39(9):1563-70.

Lin X#, Qi Q, Zheng Y, Huang T, Lathrop M, Zelenika D, Bray GA, Sacks FM, Liang L*, Lu Qi* (2015) Neuropeptide Y genotype, central obesity and abdominal fat distribution: the POUNDS LOST trial. American Journal of Clinical Nutrition 102(2):514-9.

Huang J#, Chen J#, Esparza J, Ding J, Elder JT, Abecasis GR, Lee YA, Lathrop GM, Moffatt MF, Cookson WOC, Liang L* (2015) eQTL mapping identify insertion and deletion specific eQTLs in multiple tissues. Nature Communications 6:6821.

Liang L, Willis-Owen SAG, Laprise C, Wong KCC, Davies GA, Hudson TJ, Binia A, Hopkin JM, Yang IV, Grundberg E, Busche S, Hudson M, Rönnblom L, Pastinen TM, Schwartz DA, Lathrop GM, Moffatt MF, Cookson WOC (2015) An Epigenome-Wide Association Study of Total Serum Immunoglobulin E Concentration. Nature 520(7549):670-4.

Ma B#, Huang J#, Liang L*. (2014) RTeQTL: Real-Time Online Engine for Expression Quantitative Trait Loci Analyses. Database (Oxford). 2014 Jul 18;2014. pii: bau066. doi: 10.1093/database/bau066.

Liang L, Cookson WO. (2014) Grasping nettles: cellular heterogeneity and other confounders in epigenome-wide association studies. Hum Mol Genet. 23(R1):R83-R88.

Ma B#, Wilker EH, Willis-Owen SA, Byun HM, Wong KC, Motta V, Baccarelli AA, Schwartz J, Cookson WO, Khabbaz K, Mittleman MA, Moffatt MF, Liang L*. (2014) Predicting DNA methylation level across human tissues. Nucleic Acids Research. 42(6):3515-28.

Huang J#, Chen J#, Lathrop M, Liang L*. (2013) A tool for RNA sequencing sample identity check. Bioinformatics 29(11):1463-4

Liang L, Morar N, Dixon AL, Lathrop GM, Abecasis GR, Moffatt MF, Cookson WO (2013) A cross-platform catalogue of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines. Genome Research 23(4):716-26

Cookson WOC, Liang L, Abecasis GR, Moffatt MF, Lathrop M. (2009) Mapping complex disease traits with global gene expression. Nature Reviews Genetics 10, 184-194

Guan W*, Liang L*, Boehnke M, Abecasis GR. (2009) Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies. Genet Epidemiol 33(6):508-17. DOI: 10.1002/gepi.20403

Liang L, Chen WM, Sham PC, Abecasis GR (2009). Variance components linkage analysis with repeated measurements. Human Heredity 67, 237-247

Dixon AL*, Liang L*, Moffatt MF*, Chen W, Heath S, Wong KCC, Taylor J, Gut I, Farrall M, Lathrop GM, Abecasis GR, Cookson WOC (2007). A genome-wide association study of global gene expression. Nature Genetics 39, 1202-1207

Moffatt MF*, Kabesch M*, Liang L*, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SAG, Wong KCC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR, Farrall M, Gut IG, Lathrop GM, Cookson WOC (2007). Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448, 470-473

Liang L, Zöllner S, Abecasis GR (2007). GENOME: a rapid coalescent-based whole genome simulator. Bioinformatics 23, 1565-1567

Complete list of peer reviewed publications （# advisee, ^ first/co-first author, * senior/co-senior/corresponding author）

2006

1. Li M, Atmaca-Sonmez P, Othman M, Branham KE, Khanna R, Wade MS, Li Y, Liang L, Zareparsi S, Swaroop A, Abecasis GR. (2006) CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nat Genet. 38(9):1049-1054. PMC1941700.

2007

2. Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, Demarche B, Gut I, Heath S, Foglio M, Liang L, Laukens D, Mni M, Zelenika D, Van Gossum A, Rutgeerts P, Belaiche J, Lathrop M, Georges M. (2007) Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet. 3(4):e58. PMC1853118 interests exist.
3. Moffatt MF, Kabesch M, Liang L^, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SA, Wong KC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR, Farrall M, Gut IG, Lathrop GM, Cookson WO. (2007) Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature. 448(7152):470-473. PMID: 17611496.
4. Liang L^, Zollner S, Abecasis GR. (2007) GENOME: a rapid coalescent-based whole genome simulator. Bioinformatics. 23(12):1565-1567. PMID: 17459963.
5. Dixon AL, Liang L^, Moffatt MF, Chen W, Heath S, Wong KC, Taylor J, Burnett E, Gut I, Farrall M, Lathrop GM, Abecasis GR, Cookson WO. (2007) A genome-wide association study of global gene expression. Nat Genet. 39(10):1202-1207. PMID: 17873877.

2008

6. Weidinger S, Gieger C, Rodriguez E, Baurecht H, Mempel M, Klopp N, Gohlke H, Wagenpfeil S, Ollert M, Ring J, Behrendt H, Heinrich J, Novak N, Bieber T, Kramer U, Berdel D, von Berg A, Bauer CP, Herbarth O, Koletzko S, Prokisch H, Mehta D, Meitinger T, Depner M, von Mutius E, Liang L, Moffatt M, Cookson W, Kabesch M, Wichmann HE, Illig T. (2008) Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. PLoS Genet. 4(8):e1000166. PMC2565692.

2009

7. Liang L^, Chen WM, Sham PC, Abecasis GR. (2009) Variance components linkage analysis with repeated measurements. Hum Hered. 67(4):237-247. PMC2880721.
8. Chen W, Liang L, Abecasis GR. (2009) GWAS GUI: graphical browser for the results of whole-genome association studies with high-dimensional phenotypes. Bioinformatics. 25(2):284-285. PMC2732294.
9. Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M. (2009) Mapping complex disease traits with global gene expression. Nat Rev Genet. 10(3):184-194. PMC4550035.
10. Guan W, Liang L^, Boehnke M, Abecasis GR. (2009) Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies. Genet Epidemiol. 33(6):508-517. PMC2732762.

2010

11. Ding J, Gudjonsson JE, Liang L, Stuart PE, Li Y, Chen W, Weichenthal M, Ellinghaus E, Franke A, Cookson W, Nair RP, Elder JT, Abecasis GR. (2010) Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals. Am J Hum Genet. 87(6):779-789. PMC2997368.
12. Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, Liu MC, Faruque M, Dunston GM, Watson HR, Bracken MB, Hoh J, Maul P, Maul T, Jedlicka AE, Murray T, Hetmanski JB, Ashworth R, Ongaco CM, Hetrick KN, Doheny KF, Pugh EW, Rotimi CN, Ford J, Eng C, Burchard EG, Sleiman PM, Hakonarson H, Forno E, Raby BA, Weiss ST, Scott AF, Kabesch M, Liang L, Abecasis G, Moffatt MF, Cookson WO, Ruczinski I, Beaty TH, Barnes KC. (2010) A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol. 125(2):336-346.e334. PMC3606015.
13. Sanna S, Pitzalis M, Zoledziewska M, Zara I, Sidore C, Murru R, Whalen MB, Busonero F, Maschio A, Costa G, Melis MC, Deidda F, Poddie F, Morelli L, Farina G, Li Y, Dei M, Lai S, Mulas A, Cuccuru G, Porcu E, Liang L, Zavattari P, Moi L, Deriu E, Urru MF, Bajorek M, Satta MA, Cocco E, Ferrigno P, Sotgiu S, Pugliatti M, Traccis S, Angius A, Melis M, Rosati G, Abecasis GR, Uda M, Marrosu MG, Schlessinger D, Cucca F. (2010) Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Nat Genet. 42(6):495-497. PMC3786343.
14. Hsu YH, Zillikens MC, Wilson SG, Farber CR, Demissie S, Soranzo N, Bianchi EN, Grundberg E, Liang L, Richards JB, Estrada K, Zhou Y, van Nas A, Moffatt MF, Zhai G, Hofman A, van Meurs JB, Pols HA, Price RI, Nilsson O, Pastinen T, Cupples LA, Lusis AJ, Schadt EE, Ferrari S, Uitterlinden AG, Rivadeneira F, Spector TD, Karasik D, Kiel DP. (2010) An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet. 6(6):e1000977. PMC2883588.
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18. Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segre AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Magi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, Konig IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Muller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpelainen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Pare G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietilainen KH, Pouta A, Ridderstrale M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kahonen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimaki T, Melander O, Mosley TH, Jr., Musk AW, Nieminen MS, O’Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tonjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Gronberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Volzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O’Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN. (2010) Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 467(7317):832-838. PMC2955183.
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20. Sudmant PH, Kitzman JO, Antonacci F, Alkan C, Malig M, Tsalenko A, Sampas N, Bruhn L, Shendure J, 1000 Genomes Project, Eichler EE. (2010) Diversity of human copy number variation and multicopy genes. Science. 330(6004):641-646. PMC3020103.

2011

21. Zhang M, Liang L, Xu M, Qureshi AA, Han J. (2011) Pathway analysis for genome-wide association study of basal cell carcinoma of the skin. PLoS One. 6(7):e22760. PMC3145747.
22. Chu X, Pan CM, Zhao SX, Liang J, Gao GQ, Zhang XM, Yuan GY, Li CG, Xue LQ, Shen M, Liu W, Xie F, Yang SY, Wang HF, Shi JY, Sun WW, Du WH, Zuo CL, Shi JX, Liu BL, Guo CC, Zhan M, Gu ZH, Zhang XN, Sun F, Wang ZQ, Song ZY, Zou CY, Sun WH, Guo T, Cao HM, Ma JH, Han B, Li P, Jiang H, Huang QH, Liang L, Liu LB, Chen G, Su Q, Peng YD, Zhao JJ, Ning G, Chen Z, Chen JL, Chen SJ, Huang W, Song HD. (2011) A genome-wide association study identifies two new risk loci for Graves’ disease. Nat Genet. 43(9):897-901. PMID: 21841780.
23. Mills RE, Walter K, Stewart C, Handsaker RE, Chen K, Alkan C, Abyzov A, Yoon SC, Ye K, Cheetham RK, Chinwalla A, Conrad DF, Fu Y, Grubert F, Hajirasouliha I, Hormozdiari F, Iakoucheva LM, Iqbal Z, Kang S, Kidd JM, Konkel MK, Korn J, Khurana E, Kural D, Lam HY, Leng J, Li R, Li Y, Lin CY, Luo R, Mu XJ, Nemesh J, Peckham HE, Rausch T, Scally A, Shi X, Stromberg MP, Stutz AM, Urban AE, Walker JA, Wu J, Zhang Y, Zhang ZD, Batzer MA, Ding L, Marth GT, McVean G, Sebat J, Snyder M, Wang J, Ye K, Eichler EE, Gerstein MB, Hurles ME, Lee C, McCarroll SA, Korbel JO, 1000 Genomes Project. (2011) Mapping copy number variation by population-scale genome sequencing. Nature. 470(7332):59-65. PMC3077050.
24. Gravel S, Henn BM, Gutenkunst RN, Indap AR, Marth GT, Clark AG, Yu F, Gibbs RA, 1000 Genomes Project, Bustamante CD. (2011) Demographic history and rare allele sharing among human populations. Proc Natl Acad Sci U S A. 108(29):11983-11988. PMC3142009.
25. Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedon JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van Den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD, Shi M, Faruque MU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC, Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sienra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske RF, Jr., Beaty TH, Bleecker ER, Raby BA, Meyers DA, London SJ, Gilliland FD, Burchard EG, Martinez FD, Weiss ST, Williams LK, Barnes KC, Ober C, Nicolae DL. (2011) Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet. 43(9):887-892. PMC3445408.
26. Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O’Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS, NASH CRN, GIANT Consortium, MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB, GOLD Consortium. (2011) Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 7(3):e1001324. PMC3053321.
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2012

28. Zhang M, Liang L, Morar N, Dixon AL, Lathrop GM, Ding J, Moffatt MF, Cookson WO, Kraft P, Qureshi AA, Han J. (2012) Integrating pathway analysis and genetics of gene expression for genome- wide association study of basal cell carcinoma. Hum Genet. 131(4):615-623. PMC3303995.
29. Clarke L, Zheng-Bradley X, Smith R, Kulesha E, Xiao C, Toneva I, Vaughan B, Preuss D, Leinonen R, Shumway M, Sherry S, Flicek P, 1000 Genomes Project Consortium. (2012) The 1000 Genomes Project: data management and community access. Nat Methods. 9(5):459-462. PMC3340611.
30. Cornelis MC, Glymour MM, Chang SC, Tchetgen EJ, Liang L, Koenen KC, Kang JH, Pasquale LR, Rimm EB, Kawachi I, Kubzansky LD. (2012) Oxytocin receptor (OXTR) is not associated with optimism in the Nurses’ Health Study. Mol Psychiatry. 17(12):1157-1159. PMC3587169.
31. van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan ST, Voss K, Weichenberger CX, Albers CA, Al-Hussani A, Asselbergs FW, Ciullo M, Danjou F, Dina C, Esko T, Evans DM, Franke L, Gogele M, Hartiala J, Hersch M, Holm H, Hottenga JJ, Kanoni S, Kleber ME, Lagou V, Langenberg C, Lopez LM, Lyytikainen LP, Melander O, Murgia F, Nolte IM, O’Reilly PF, Padmanabhan S, Parsa A, Pirastu N, Porcu E, Portas L, Prokopenko I, Ried JS, Shin SY, Tang CS, Teumer A, Traglia M, Ulivi S, Westra HJ, Yang J, Zhao JH, Anni F, Abdellaoui A, Attwood A, Balkau B, Bandinelli S, Bastardot F, Benyamin B, Boehm BO, Cookson WO, Das D, de Bakker PI, de Boer RA, de Geus EJ, de Moor MH, Dimitriou M, Domingues FS, Doring A, Engstrom G, Eyjolfsson GI, Ferrucci L, Fischer K, Galanello R, Garner SF, Genser B, Gibson QD, Girotto G, Gudbjartsson DF, Harris SE, Hartikainen AL, Hastie CE, Hedblad B, Illig T, Jolley J, Kahonen M, Kema IP, Kemp JP, Liang L, Lloyd-Jones H, Loos RJ, Meacham S, Medland SE, Meisinger C, Memari Y, Mihailov E, Miller K, Moffatt MF, Nauck M, Novatchkova M, Nutile T, Olafsson I, Onundarson PT, Parracciani D, Penninx BW, Perseu L, Piga A, Pistis G, Pouta A, Puc U, Raitakari O, Ring SM, Robino A, Ruggiero D, Ruokonen A, Saint-Pierre A, Sala C, Salumets A, Sambrook J, Schepers H, Schmidt CO, Sillje HH, Sladek R, Smit JH, Starr JM, Stephens J, Sulem P, Tanaka T, Thorsteinsdottir U, Tragante V, van Gilst WH, van Pelt LJ, van Veldhuisen DJ, Volker U, Whitfield JB, Willemsen G, Winkelmann BR, Wirnsberger G, Algra A, Cucca F, d’Adamo AP, Danesh J, Deary IJ, Dominiczak AF, Elliott P, Fortina P, Froguel P, Gasparini P, Greinacher A, Hazen SL, Jarvelin MR, Khaw KT, Lehtimaki T, Maerz W, Martin NG, Metspalu A, Mitchell BD, Montgomery GW, Moore C, Navis G, Pirastu M, Pramstaller PP, Ramirez-Solis R, Schadt E, Scott J, Shuldiner AR, Smith GD, Smith JG, Snieder H, Sorice R, Spector TD, Stefansson K, Stumvoll M, Tang WH, Toniolo D, Tonjes A, Visscher PM, Vollenweider P, Wareham NJ, Wolffenbuttel BH, Boomsma DI, Beckmann JS, Dedoussis GV, Deloukas P, Ferreira MA, Sanna S, Uda M, Hicks AA, Penninger JM, Gieger C, Kooner JS, Ouwehand WH, Soranzo N, Chambers JC. (2012) Seventy-five genetic loci influencing the human red blood cell. Nature. 492(7429):369-375. PMC3623669.
32. Cornelis MC, Tchetgen EJ, Liang L, Qi L, Chatterjee N, Hu FB, Kraft P. (2012) Gene-environment interactions in genome-wide association studies: a comparative study of tests applied to empirical studies of type 2 diabetes. Am J Epidemiol. 175(3):191-202. PMC3261439.
33. Salm MP, Horswell SD, Hutchison CE, Speedy HE, Yang X, Liang L, Schadt EE, Cookson WO, Wierzbicki AS, Naoumova RP, Shoulders CC. (2012) The origin, global distribution, and functional impact of the human 8p23 inversion polymorphism. Genome Res. 22(6):1144-1153. PMC3371712.
34. Edgren G, Liang L, Adami HO, Chang ET. (2012) Enigmatic sex disparities in cancer incidence. Eur J Epidemiol. 27(3):187-196. PMID: 22212865.
35. Qi Q, Liang L, Doria A, Hu FB, Qi L. (2012) Genetic predisposition to dyslipidemia and type 2 diabetes risk in two prospective cohorts. Diabetes. 61(3):745-752. PMC3282815.
36. Pasaniuc B, Rohland N, McLaren PJ, Garimella K, Zaitlen N, Li H, Gupta N, Neale BM, Daly MJ, Sklar P, Sullivan PF, Bergen S, Moran JL, Hultman CM, Lichtenstein P, Magnusson P, Purcell SM, Haas DW, Liang L, Sunyaev S, Patterson N, de Bakker PI, Reich D, Price AL. (2012) Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nat Genet. 44(6):631-635. PMC3400344.
37. Qi Q, Menzaghi C, Smith S, Liang L, de Rekeneire N, Garcia ME, Lohman KK, Miljkovic I, Strotmeyer ES, Cummings SR, Kanaya AM, Tylavsky FA, Satterfield S, Ding J, Rimm EB, Trischitta V, Hu FB, Liu Y, Qi L. (2012) Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels. Hum Mol Genet. 21(21):4774-4780. PMC3471394.
38. Wu C, Kraft P, Zhai K, Chang J, Wang Z, Li Y, Hu Z, He Z, Jia W, Abnet CC, Liang L, Hu N, Miao X, Zhou Y, Liu Z, Zhan Q, Liu Y, Qiao Y, Zhou Y, Jin G, Guo C, Lu C, Yang H, Fu J, Yu D, Freedman ND, Ding T, Tan W, Goldstein AM, Wu T, Shen H, Ke Y, Zeng Y, Chanock SJ, Taylor PR, Lin D. (2012) Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. Nat Genet. 44(10):1090-1097. PMID: 22960999.
39. Meng S, Zhang M, Liang L, Han J. (2012) Current opportunities and challenges: genome-wide association studies on pigmentation and skin cancer. Pigment Cell Melanoma Res. 25(5):612-617. PMID: 22762390.

2013

40. Walter S, Glymour MM, Koenen K, Liang L, Tchetgen Tchetgen EJ, Cornelis M, Chang SC, Rimm E, Kawachi I, Kubzansky LD. (2013) Performance of polygenic scores for predicting phobic anxiety. PLoS One. 8(11):e80326. PMC3835914.
41. Zhao SX, Liu W, Zhan M, Song ZY, Yang SY, Xue LQ, Pan CM, Gu ZH, Liu BL, Wang HN, Liang L, Liang J, Zhang XM, Yuan GY, Li CG, Chen MD, Chen JL, Gao GQ, Song HD. (2013) A refined study of FCRL genes from a genome-wide association study for Graves’ disease. PLoS One. 8(3):e57758. PMC3591391.
42. Li L, Kabesch M, Bouzigon E, Demenais F, Farrall M, Moffatt MF, Lin X, Liang L*. (2013) Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma. Front Genet. 4(103. PMC3668139.
43. Workalemahu T, Enquobahrie DA, Moore A, Sanchez SE, Ananth CV, Pacora PN, Liang L, Salazar M, Williams MA. (2013) Genome-wide and candidate gene association studies of placental abruption. Int J Mol Epidemiol Genet. 4(3):128-139. PMC3773564.
44. Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaelsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, Viikari J, Lohman KK, Ferrucci L, Melhus H, Ingelsson E, Byberg L, Lind L, Lorentzon M, Salomaa V, Campbell H, Dunlop M, Mitchell BD, Herzig KH, Pouta A, Hartikainen AL, Genetic Investigation of Anthropometric Traits-GIANT Consortium, Streeten EA, Theodoratou E, Jula A, Wareham NJ, Ohlsson C, Frayling TM, Kritchevsky SB, Spector TD, Richards JB, Lehtimaki T, Ouwehand WH, Kraft P, Cooper C, Marz W, Power C, Loos RJ, Wang TJ, Jarvelin MR, Whittaker JC, Hingorani AD, Hypponen E. (2013) Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 10(2):e1001383. PMC3564800.
45. Liang L^, Morar N, Dixon AL, Lathrop GM, Abecasis GR, Moffatt MF, Cookson WO. (2013) A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines. Genome Res. 23(4):716-726. PMC3613588.
46. Pandey RC, Michel S, Schieck M, Binia A, Liang L, Klopp N, Franke A, von Berg A, Bufe A, Rietschel E, Heinzmann A, Laub O, Simma B, Frischer T, Genuneit J, Illig T, Kabesch M. (2013) Polymorphisms in extracellular signal-regulated kinase family influence genetic susceptibility to asthma. J Allergy Clin Immunol. 131(4):1245-1247. PMID: 23384682.
47. Berndt SI, Skibola CF, Joseph V, Camp NJ, Nieters A, Wang Z, Cozen W, Monnereau A, Wang SS, Kelly RS, Lan Q, Teras LR, Chatterjee N, Chung CC, Yeager M, Brooks-Wilson AR, Hartge P, Purdue MP, Birmann BM, Armstrong BK, Cocco P, Zhang Y, Severi G, Zeleniuch-Jacquotte A, Lawrence C, Burdette L, Yuenger J, Hutchinson A, Jacobs KB, Call TG, Shanafelt TD, Novak AJ, Kay NE, Liebow M, Wang AH, Smedby KE, Adami HO, Melbye M, Glimelius B, Chang ET, Glenn M, Curtin K, Cannon-Albright LA, Jones B, Diver WR, Link BK, Weiner GJ, Conde L, Bracci PM, Riby J, Holly EA, Smith MT, Jackson RD, Tinker LF, Benavente Y, Becker N, Boffetta P, Brennan P, Foretova L, Maynadie M, McKay J, Staines A, Rabe KG, Achenbach SJ, Vachon CM, Goldin LR, Strom SS, Lanasa MC, Spector LG, Leis JF, Cunningham JM, Weinberg JB, Morrison VA, Caporaso NE, Norman AD, Linet MS, De Roos AJ, Morton LM, Severson RK, Riboli E, Vineis P, Kaaks R, Trichopoulos D, Masala G, Weiderpass E, Chirlaque MD, Vermeulen RC, Travis RC, Giles GG, Albanes D, Virtamo J, Weinstein S, Clavel J, Zheng T, Holford TR, Offit K, Zelenetz A, Klein RJ, Spinelli JJ, Bertrand KA, Laden F, Giovannucci E, Kraft P, Kricker A, Turner J, Vajdic CM, Ennas MG, Ferri GM, Miligi L, Liang L, Sampson J, Crouch S, Park JH, North KE, Cox A, Snowden JA, Wright J, Carracedo A, Lopez-Otin C, Bea S, Salaverria I, Martin-Garcia D, Campo E, Fraumeni JF, Jr., de Sanjose S, Hjalgrim H, Cerhan JR, Chanock SJ, Rothman N, Slager SL. (2013) Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. Nat Genet. 45(8):868-876. PMC3729927.
48. Binia A, Van Stiphout N, Liang L, Michel S, Bhavsar PK, Fan Chung K, Brightling CE, Barnes PJ, Kabesch M, Bush A, Cookson WO, Moffatt MF. (2013) A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children. Hum Mutat. 34(8):1131-1139. PMC4296222.
49. Esparza-Gordillo J, Schaarschmidt H, Liang L, Cookson W, Bauerfeind A, Lee-Kirsch MA, Nemat K, Henderson J, Paternoster L, Harper JI, Mangold E, Nothen MM, Ruschendorf F, Kerscher T, Marenholz I, Matanovic A, Lau S, Keil T, Bauer CP, Kurek M, Ciechanowicz A, Macek M, Franke A, Kabesch M, Hubner N, Abecasis G, Weidinger S, Moffatt M, Lee YA. (2013) A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis. J Allergy Clin Immunol. 132(2):371-377. PMID: 23582566.
50. Hu YJ, Berndt SI, Gustafsson S, Ganna A, Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Hirschhorn J, North KE, Ingelsson E, Lin DY. (2013) Meta-analysis of gene-level associations for rare variants based on single-variant statistics. Am J Hum Genet. 93(2):236-248. PMC3738834.
51. Zhao SX, Xue LQ, Liu W, Gu ZH, Pan CM, Yang SY, Zhan M, Wang HN, Liang J, Gao GQ, Zhang XM, Yuan GY, Li CG, Du WH, Liu BL, Liu LB, Chen G, Su Q, Peng YD, Zhao JJ, Ning G, Huang W, Liang L, Qi L, Chen SJ, Chen Z, Chen JL, Song HD. (2013) Robust evidence for five new Graves’ disease risk loci from a staged genome-wide association analysis. Hum Mol Genet. 22(16):3347-3362. PMID: 23612905.
52. Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O’Regan GM, Beattie P, Folster-Holst R, Franke A, Novak N, Fahy CM, Winge MC, Kabesch M, Illig T, Heath S, Soderhall C, Melen E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, McLean WH, Brown SJ, Cookson WO, Lathrop GM, Irvine AD, Moffatt MF. (2013) A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis. Hum Mol Genet. 22(23):4841-4856. PMC3820131.
53. Pandey RC, Michel S, Tesse R, Binia A, Schedel M, Liang L, Klopp N, Franke A, von Berg A, Bufe A, Rietschel E, Heinzmann A, Laub O, Simma B, Frischer T, Genuneit J, Illig T, Kabesch M. (2013) Genetic variation in the Toll-like receptor signaling pathway is associated with childhood asthma. J Allergy Clin Immunol. 131(2):602-605. PMID: 23273951.
54. Paul DS, Albers CA, Rendon A, Voss K, Stephens J, HaemGen Consortium, van der Harst P, Chambers JC, Soranzo N, Ouwehand WH, Deloukas P. (2013) Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome Res. 23(7):1130-1141. PMC3698506.
55. Li X, Liang L, Zhang M, Song F, Nan H, Wang LE, Wei Q, Lee JE, Amos CI, Qureshi AA, Han J. (2013) Obesity-related genetic variants, human pigmentation, and risk of melanoma. Hum Genet. 132(7):793-801. PMC3683389.
56. Zhang M, Song F, Liang L, Nan H, Zhang J, Liu H, Wang LE, Wei Q, Lee JE, Amos CI, Kraft P, Qureshi AA, Han J. (2013) Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Hum Mol Genet. 22(14):2948-2959. PMC3690971.
57. Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpelainen TO, Esko T, Magi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, Vedantam S, Wood AR, Liang L, Steinthorsdottir V, Thorleifsson G, Dermitzakis ET, Dimas AS, Karpe F, Min JL, Nicholson G, Clegg DJ, Person T, Krohn JP, Bauer S, Buechler C, Eisinger K, Bonnefond A, Froguel P, Hottenga JJ, Prokopenko I, Waite LL, Harris TB, Smith AV, Shuldiner AR, McArdle WL, Caulfield MJ, Munroe PB, Gronberg H, Chen YD, Li G, Beckmann JS, Johnson T, Thorsteinsdottir U, Teder-Laving M, Khaw KT, Wareham NJ, Zhao JH, Amin N, Oostra BA, Kraja AT, Province MA, Cupples LA, Heard-Costa NL, Kaprio J, Ripatti S, Surakka I, Collins FS, Saramies J, Tuomilehto J, Jula A, Salomaa V, Erdmann J, Hengstenberg C, Loley C, Schunkert H, Lamina C, Wichmann HE, Albrecht E, Gieger C, Hicks AA, Johansson A, Pramstaller PP, Kathiresan S, Speliotes EK, Penninx B, Hartikainen AL, Jarvelin MR, Gyllensten U, Boomsma DI, Campbell H, Wilson JF, Chanock SJ, Farrall M, Goel A, Medina-Gomez C, Rivadeneira F, Estrada K, Uitterlinden AG, Hofman A, Zillikens MC, den Heijer M, Kiemeney LA, Maschio A, Hall P, Tyrer J, Teumer A, Volzke H, Kovacs P, Tonjes A, Mangino M, Spector TD, Hayward C, Rudan I, Hall AS, Samani NJ, Attwood AP, Sambrook JG, Hung J, Palmer LJ, Lokki ML, Sinisalo J, Boucher G, Huikuri H, Lorentzon M, Ohlsson C, Eklund N, Eriksson JG, Barlassina C, Rivolta C, Nolte IM, Snieder H, Van der Klauw MM, Van Vliet-Ostaptchouk JV, Gejman PV, Shi J, Jacobs KB, Wang Z, Bakker SJ, Mateo Leach I, Navis G, van der Harst P, Martin NG, Medland SE, Montgomery GW, Yang J, Chasman DI, Ridker PM, Rose LM, Lehtimaki T, Raitakari O, Absher D, Iribarren C, Basart H, Hovingh KG, Hypponen E, Power C, Anderson D, Beilby JP, Hui J, Jolley J, Sager H, Bornstein SR, Schwarz PE, Kristiansson K, Perola M, Lindstrom J, Swift AJ, Uusitupa M, Atalay M, Lakka TA, Rauramaa R, Bolton JL, Fowkes G, Fraser RM, Price JF, Fischer K, Krjuta Kov K, Metspalu A, Mihailov E, Langenberg C, Luan J, Ong KK, Chines PS, Keinanen-Kiukaanniemi SM, Saaristo TE, Edkins S, Franks PW, Hallmans G, Shungin D, Morris AD, Palmer CN, Erbel R, Moebus S, Nothen MM, Pechlivanis S, Hveem K, Narisu N, Hamsten A, Humphries SE, Strawbridge RJ, Tremoli E, Grallert H, Thorand B, Illig T, Koenig W, Muller-Nurasyid M, Peters A, Boehm BO, Kleber ME, Marz W, Winkelmann BR, Kuusisto J, Laakso M, Arveiler D, Cesana G, Kuulasmaa K, Virtamo J, Yarnell JW, Kuh D, Wong A, Lind L, de Faire U, Gigante B, Magnusson PK, Pedersen NL, Dedoussis G, Dimitriou M, Kolovou G, Kanoni S, Stirrups K, Bonnycastle LL, Njolstad I, Wilsgaard T, Ganna A, Rehnberg E, Hingorani A, Kivimaki M, Kumari M, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox CS, Frayling T, Groop LC, Haritunians T, Hunter D, Ingelsson E, Kaplan R, Mohlke KL, O’Connell JR, Schlessinger D, Strachan DP, Stefansson K, van Duijn CM, Abecasis GR, McCarthy MI, Hirschhorn JN, Qi L, Loos RJ, Lindgren CM, North KE, Heid IM. (2013) Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet. 9(6):e1003500. PMC3674993 Kari Stefansson, Valgerdur Steinthorsdottir, and Gudmar Thorleifsson are employed by deCODE Genetics with stock/stock options in the company. Ines Barroso and spouse own stock in Incyte Ltd and GlaxoSmithKline. Nilesh J Samani holds a Chair supported by the British Heart Foundation and is an NIHR Senior Investigator.
58. Huang J#, Chen J#, Lathrop M, Liang L*. (2013) A tool for RNA sequencing sample identity check. Bioinformatics. 29(11):1463-1464. PMID: 23559639.
59. Berndt SI, Gustafsson S, Magi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu T, Hu YJ, Lee SH, Liang L, Lin DY, Min JL, Neale BM, Thorleifsson G, Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N, Fischer K, Goel A, Hottenga JJ, Huffman JE, Jarick I, Johansson A, Johnson T, Kanoni S, Kleber ME, Konig IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C, Li G, Mangino M, McArdle WL, Medina-Gomez C, Muller-Nurasyid M, Ngwa JS, Nolte IM, Paternoster L, Pechlivanis S, Perola M, Peters MJ, Preuss M, Rose LM, Shi J, Shungin D, Smith AV, Strawbridge RJ, Surakka I, Teumer A, Trip MD, Tyrer J, Van Vliet-Ostaptchouk JV, Vandenput L, Waite LL, Zhao JH, Absher D, Asselbergs FW, Atalay M, Attwood AP, Balmforth AJ, Basart H, Beilby J, Bonnycastle LL, Brambilla P, Bruinenberg M, Campbell H, Chasman DI, Chines PS, Collins FS, Connell JM, Cookson WO, de Faire U, de Vegt F, Dei M, Dimitriou M, Edkins S, Estrada K, Evans DM, Farrall M, Ferrario MM, Ferrieres J, Franke L, Frau F, Gejman PV, Grallert H, Gronberg H, Gudnason V, Hall AS, Hall P, Hartikainen AL, Hayward C, Heard-Costa NL, Heath AC, Hebebrand J, Homuth G, Hu FB, Hunt SE, Hypponen E, Iribarren C, Jacobs KB, Jansson JO, Jula A, Kahonen M, Kathiresan S, Kee F, Khaw KT, Kivimaki M, Koenig W, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Laitinen JH, Lakka TA, Langenberg C, Launer LJ, Lind L, Lindstrom J, Liu J, Liuzzi A, Lokki ML, Lorentzon M, Madden PA, Magnusson PK, Manunta P, Marek D, Marz W, Mateo Leach I, McKnight B, Medland SE, Mihailov E, Milani L, Montgomery GW, Mooser V, Muhleisen TW, Munroe PB, Musk AW, Narisu N, Navis G, Nicholson G, Nohr EA, Ong KK, Oostra BA, Palmer CN, Palotie A, Peden JF, Pedersen N, Peters A, Polasek O, Pouta A, Pramstaller PP, Prokopenko I, Putter C, Radhakrishnan A, Raitakari O, Rendon A, Rivadeneira F, Rudan I, Saaristo TE, Sambrook JG, Sanders AR, Sanna S, Saramies J, Schipf S, Schreiber S, Schunkert H, Shin SY, Signorini S, Sinisalo J, Skrobek B, Soranzo N, Stancakova A, Stark K, Stephens JC, Stirrups K, Stolk RP, Stumvoll M, Swift AJ, Theodoraki EV, Thorand B, Tregouet DA, Tremoli E, Van der Klauw MM, van Meurs JB, Vermeulen SH, Viikari J, Virtamo J, Vitart V, Waeber G, Wang Z, Widen E, Wild SH, Willemsen G, Winkelmann BR, Witteman JC, Wolffenbuttel BH, Wong A, Wright AF, Zillikens MC, Amouyel P, Boehm BO, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Cupples LA, Cusi D, Dedoussis GV, Erdmann J, Eriksson JG, Franks PW, Froguel P, Gieger C, Gyllensten U, Hamsten A, Harris TB, Hengstenberg C, Hicks AA, Hingorani A, Hinney A, Hofman A, Hovingh KG, Hveem K, Illig T, Jarvelin MR, Jockel KH, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kuh D, Laakso M, Lehtimaki T, Levinson DF, Martin NG, Metspalu A, Morris AD, Nieminen MS, Njolstad I, Ohlsson C, Oldehinkel AJ, Ouwehand WH, Palmer LJ, Penninx B, Power C, Province MA, Psaty BM, Qi L, Rauramaa R, Ridker PM, Ripatti S, Salomaa V, Samani NJ, Snieder H, Sorensen TI, Spector TD, Stefansson K, Tonjes A, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Vollenweider P, Wallaschofski H, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Abecasis GR, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox CS, Frayling T, Groop LC, Haritunian T, Heid IM, Hunter D, Kaplan RC, Karpe F, Moffatt MF, Mohlke KL, O’Connell JR, Pawitan Y, Schadt EE, Schlessinger D, Steinthorsdottir V, Strachan DP, Thorsteinsdottir U, van Duijn CM, Visscher PM, Di Blasio AM, Hirschhorn JN, Lindgren CM, Morris AP, Meyre D, Scherag A, McCarthy MI, Speliotes EK, North KE, Loos RJ, Ingelsson E. (2013) Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 45(5):501-512. PMC3973018.
60. Machiela MJ, Chen C, Liang L, Diver WR, Stevens VL, Tsilidis KK, Haiman CA, Chanock SJ, Hunter DJ, Kraft P. (2013) One thousand genomes imputation in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium aggressive prostate cancer genome- wide association study. Prostate. 73(7):677-689. PMC3962143.
61. Qi Q, Xu M, Wu H, Liang L, Champagne CM, Bray GA, Sacks FM, Qi L. (2013) IRS1 genotype modulates metabolic syndrome reversion in response to 2-year weight-loss diet intervention: the POUNDS LOST trial. Diabetes Care. 36(11):3442-3447. PMC3816909.
62. Evans DM, Brion MJ, Paternoster L, Kemp JP, McMahon G, Munafo M, Whitfield JB, Medland SE, Montgomery GW, GIANT Consortium, Timpson NJ, St Pourcain B, Lawlor DA, Martin NG, Dehghan A, Hirschhorn J, Smith GD. (2013) Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet. 9(10):e1003919. PMC3814299.

2014

63. Cornelis MC, Chiuve SE, Glymour MM, Chang SC, Tchetgen Tchetgen EJ, Liang L, Koenen KC, Rimm EB, Kawachi I, Kubzansky LD. (2014) Bachelors, divorcees, and widowers: does marriage protect men from type 2 diabetes? PLoS One. 9(9):e106720. PMC4167705.
64. Ma B#, Huang J#, Liang L*. (2014) RTeQTL: Real-Time Online Engine for Expression Quantitative Trait Loci Analyses. Database (Oxford). 2014(PMC4103423.
65. Ma B#, Wilker EH, Willis-Owen SA, Byun HM, Wong KC, Motta V, Baccarelli AA, Schwartz J, Cookson WO, Khabbaz K, Mittleman MA, Moffatt MF, Liang L*. (2014) Predicting DNA methylation level across human tissues. Nucleic Acids Res. 42(6):3515-3528. PMC3973306.
66. Irvin MR, Zhi D, Joehanes R, Mendelson M, Aslibekyan S, Claas SA, Thibeault KS, Patel N, Day K, Jones LW, Liang L, Chen BH, Yao C, Tiwari HK, Ordovas JM, Levy D, Absher D, Arnett DK. (2014) Epigenome-wide association study of fasting blood lipids in the Genetics of Lipid-lowering Drugs and Diet Network study. Circulation. 130(7):565-572. PMC4209699.
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68. Chang SC, Glymour MM, Rewak M, Cornelis MC, Walter S, Koenen KC, Kawachi I, Liang L, Tchetgen Tchetgen EJ, Kubzansky LD. (2014) Are genetic variations in OXTR, AVPR1A, and CD38 genes important to social integration? Results from two large U.S. cohorts. Psychoneuroendocrinology. 39(257-268. PMC3864016.
69. Hoggart CJ, Venturini G, Mangino M, Gomez F, Ascari G, Zhao JH, Teumer A, Winkler TW, Tsernikova N, Luan J, Mihailov E, Ehret GB, Zhang W, Lamparter D, Esko T, Mace A, Rueger S, Bochud PY, Barcella M, Dauvilliers Y, Benyamin B, Evans DM, Hayward C, Lopez MF, Franke L, Russo A, Heid IM, Salvi E, Vendantam S, Arking DE, Boerwinkle E, Chambers JC, Fiorito G, Grallert H, Guarrera S, Homuth G, Huffman JE, Porteous D, Generation Scotland Consortium, LifeLines Cohort Study, GIANT Consortium, Moradpour D, Iranzo A, Hebebrand J, Kemp JP, Lammers GJ, Aubert V, Heim MH, Martin NG, Montgomery GW, Peraita-Adrados R, Santamaria J, Negro F, Schmidt CO, Scott RA, Spector TD, Strauch K, Volzke H, Wareham NJ, Yuan W, Bell JT, Chakravarti A, Kooner JS, Peters A, Matullo G, Wallaschofski H, Whitfield JB, Paccaud F, Vollenweider P, Bergmann S, Beckmann JS, Tafti M, Hastie ND, Cusi D, Bochud M, Frayling TM, Metspalu A, Jarvelin MR, Scherag A, Smith GD, Borecki IB, Rousson V, Hirschhorn JN, Rivolta C, Loos RJ, Kutalik Z. (2014) Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genet. 10(7):e1004508. PMC4117451.
70. van der Valk RJ, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA, Genuneit J, Kerhof M, Kreiner-Moller E, Caceres A, Gref A, Liang LL, Taal HR, Bouzigon E, Demenais F, Nadif R, Ober C, Thompson EE, Estrada K, Hofman A, Uitterlinden AG, van Duijn C, Rivadeneira F, Li X, Eckel SP, Berhane K, Gauderman WJ, Granell R, Evans DM, St Pourcain B, McArdle W, Kemp JP, Smith GD, Tiesler CM, Flexeder C, Simpson A, Murray CS, Fuchs O, Postma DS, Bonnelykke K, Torrent M, Andersson M, Sleiman P, Hakonarson H, Cookson WO, Moffatt MF, Paternoster L, Melen E, Sunyer J, Bisgaard H, Koppelman GH, Ege M, Custovic A, Heinrich J, Gilliland FD, Henderson AJ, Jaddoe VW, de Jongste JC. (2014) Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. J Allergy Clin Immunol. 134(1):46-55. PMC4334587.
71. Chang SC, Glymour MM, Walter S, Liang L, Koenen KC, Tchetgen EJ, Cornelis MC, Kawachi I, Rimm E, Kubzansky LD. (2014) Genome-wide polygenic scoring for a 14-year long-term average depression phenotype. Brain Behav. 4(2):298-311. PMC3967544.
72. Zhang Y, Yi P, Chen W, Ming J, Zhu B, Li Z, Shen N, Shi W, Ke J, Zhao Q, Lu X, Xun X, Liu L, Song R, Guo H, Zhong R, Liang L, Huang T, Miao X. (2014) Association between polymorphisms within the susceptibility region 8q24 and breast cancer in a Chinese population. Tumour Biol. 35(3):2649-2654. PMID: 24414391.
73. Qi Q, Chu AY, Kang JH, Huang J, Rose LM, Jensen MK, Liang L, Curhan GC, Pasquale LR, Wiggs JL, De Vivo I, Chan AT, Choi HK, Tamimi RM, Ridker PM, Hunter DJ, Willett WC, Rimm EB, Chasman DI, Hu FB, Qi L. (2014) Fried food consumption, genetic risk, and body mass index: gene-diet interaction analysis in three US cohort studies. Bmj. 348(g1610. PMC3959253.
74. Winkler TW, Day FR, Croteau-Chonka DC, Wood AR, Locke AE, Magi R, Ferreira T, Fall T, Graff M, Justice AE, Luan J, Gustafsson S, Randall JC, Vedantam S, Workalemahu T, Kilpelainen TO, Scherag A, Esko T, Kutalik Z, Heid IM, Loos RJ, Genetic Investigation of ANthropometric Traits (GIANT) Consortium. (2014) Quality control and conduct of genome-wide association meta-analyses. Nat Protoc. 9(5):1192-1212. PMC4083217.
75. Cerhan JR, Berndt SI, Vijai J, Ghesquieres H, McKay J, Wang SS, Wang Z, Yeager M, Conde L, de Bakker PI, Nieters A, Cox D, Burdett L, Monnereau A, Flowers CR, De Roos AJ, Brooks-Wilson AR, Lan Q, Severi G, Melbye M, Gu J, Jackson RD, Kane E, Teras LR, Purdue MP, Vajdic CM, Spinelli JJ, Giles GG, Albanes D, Kelly RS, Zucca M, Bertrand KA, Zeleniuch-Jacquotte A, Lawrence C, Hutchinson A, Zhi D, Habermann TM, Link BK, Novak AJ, Dogan A, Asmann YW, Liebow M, Thompson CA, Ansell SM, Witzig TE, Weiner GJ, Veron AS, Zelenika D, Tilly H, Haioun C, Molina TJ, Hjalgrim H, Glimelius B, Adami HO, Bracci PM, Riby J, Smith MT, Holly EA, Cozen W, Hartge P, Morton LM, Severson RK, Tinker LF, North KE, Becker N, Benavente Y, Boffetta P, Brennan P, Foretova L, Maynadie M, Staines A, Lightfoot T, Crouch S, Smith A, Roman E, Diver WR, Offit K, Zelenetz A, Klein RJ, Villano DJ, Zheng T, Zhang Y, Holford TR, Kricker A, Turner J, Southey MC, Clavel J, Virtamo J, Weinstein S, Riboli E, Vineis P, Kaaks R, Trichopoulos D, Vermeulen RC, Boeing H, Tjonneland A, Angelucci E, Di Lollo S, Rais M, Birmann BM, Laden F, Giovannucci E, Kraft P, Huang J#, Ma B#, Ye Y, Chiu BC, Sampson J, Liang L, Park JH, Chung CC, Weisenburger DD, Chatterjee N, Fraumeni JF, Jr., Slager SL, Wu X, de Sanjose S, Smedby KE, Salles G, Skibola CF, Rothman N, Chanock SJ. (2014) Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma. Nat Genet. 46(11):1233-1238. PMC4213349.
76. Skibola CF, Berndt SI, Vijai J, Conde L, Wang Z, Yeager M, de Bakker PI, Birmann BM, Vajdic CM, Foo JN, Bracci PM, Vermeulen RC, Slager SL, de Sanjose S, Wang SS, Linet MS, Salles G, Lan Q, Severi G, Hjalgrim H, Lightfoot T, Melbye M, Gu J, Ghesquieres H, Link BK, Morton LM, Holly EA, Smith A, Tinker LF, Teras LR, Kricker A, Becker N, Purdue MP, Spinelli JJ, Zhang Y, Giles GG, Vineis P, Monnereau A, Bertrand KA, Albanes D, Zeleniuch-Jacquotte A, Gabbas A, Chung CC, Burdett L, Hutchinson A, Lawrence C, Montalvan R, Liang L, Huang J#, Ma B#, Liu J, Adami HO, Glimelius B, Ye Y, Nowakowski GS, Dogan A, Thompson CA, Habermann TM, Novak AJ, Liebow M, Witzig TE, Weiner GJ, Schenk M, Hartge P, De Roos AJ, Cozen W, Zhi D, Akers NK, Riby J, Smith MT, Lacher M, Villano DJ, Maria A, Roman E, Kane E, Jackson RD, North KE, Diver WR, Turner J, Armstrong BK, Benavente Y, Boffetta P, Brennan P, Foretova L, Maynadie M, Staines A, McKay J, Brooks-Wilson AR, Zheng T, Holford TR, Chamosa S, Kaaks R, Kelly RS, Ohlsson B, Travis RC, Weiderpass E, Clavel J, Giovannucci E, Kraft P, Virtamo J, Mazza P, Cocco P, Ennas MG, Chiu BC, Fraumeni JF, Jr., Nieters A, Offit K, Wu X, Cerhan JR, Smedby KE, Chanock SJ, Rothman N. (2014) Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region. Am J Hum Genet. 95(4):462-471. PMC4185120.
77. Liu CT, Buchkovich ML, Winkler TW, Heid IM, African Ancestry Anthropometry Genetics Consortium, GIANT Consortium, Borecki IB, Fox CS, Mohlke KL, North KE, Adrienne Cupples L. (2014) Multi-ethnic fine-mapping of 14 central adiposity loci. Hum Mol Genet. 23(17):4738-4744. PMC4119415.
78. Liang L^, Cookson WO. (2014) Grasping nettles: cellular heterogeneity and other confounders in epigenome-wide association studies. Hum Mol Genet. 23(R1):R83-88. PMC4170720.

2015

79. Croteau-Chonka DC, Rogers AJ, Raj T, McGeachie MJ, Qiu W, Ziniti JP, Stubbs BJ, Liang L, Martinez FD, Strunk RC, Lemanske RF, Jr., Liu AH, Stranger BE, Carey VJ, Raby BA. (2015) Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation. PLoS One. 10(10):e0140758. PMC4608673.
80. Martinez-Gonzalez MA, Ruiz-Canela M, Hruby A, Liang L, Trichopoulou A, Hu FB. (2015) Intervention Trials with the Mediterranean Diet in Cardiovascular Prevention: Understanding Potential Mechanisms through Metabolomic Profiling. J Nutr. 146(4):913s-919s. PMC4807639.
81. Liang L^, Willis-Owen SAG, Laprise C, Wong KCC, Davies GA, Hudson TJ, Binia A, Hopkin JM, Yang IV, Grundberg E, Busche S, Hudson M, Ronnblom L, Pastinen TM, Schwartz DA, Lathrop GM, Moffatt MF, Cookson W. (2015) An epigenome-wide association study of total serum immunoglobulin E concentration. Nature. 520(7549):670-674. PMC4416961.
82. Lin X#, Qi Q, Zheng Y, Huang T, Lathrop M, Zelenika D, Bray GA, Sacks FM, Liang L*, Qi L. (2015) Neuropeptide Y genotype, central obesity, and abdominal fat distribution: the POUNDS LOST trial. Am J Clin Nutr. 102(2):514-519. PMC4515864.
83. Demerath EW, Guan W, Grove ML, Aslibekyan S, Mendelson M, Zhou YH, Hedman AK, Sandling JK, Li LA, Irvin MR, Zhi D, Deloukas P, Liang L, Liu C, Bressler J, Spector TD, North K, Li Y, Absher DM, Levy D, Arnett DK, Fornage M, Pankow JS, Boerwinkle E. (2015) Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci. Hum Mol Genet. 24(15):4464-4479. PMC4492394.
84. Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Magi R, Reschen ME, Mahajan A, Locke A, Rayner NW, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Franberg M, Strawbridge RJ, Kestler H, Chheda H, Eisele L, Gustafsson S, Steinthorsdottir V, Thorleifsson G, Qi L, Karssen LC, van Leeuwen EM, Willems SM, Li M, Chen H, Fuchsberger C, Kwan P, Ma C, Linderman M, Lu Y, Thomsen SK, Rundle JK, Beer NL, van de Bunt M, Chalisey A, Kang HM, Voight BF, Abecasis GR, Almgren P, Baldassarre D, Balkau B, Benediktsson R, Bluher M, Boeing H, Bonnycastle LL, Bottinger EP, Burtt NP, Carey J, Charpentier G, Chines PS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Doney AS, Dorkhan M, Edkins S, Eriksson JG, Esko T, Eury E, Fadista J, Flannick J, Fontanillas P, Fox C, Franks PW, Gertow K, Gieger C, Gigante B, Gottesman O, Grant GB, Grarup N, Groves CJ, Hassinen M, Have CT, Herder C, Holmen OL, Hreidarsson AB, Humphries SE, Hunter DJ, Jackson AU, Jonsson A, Jorgensen ME, Jorgensen T, Kao WH, Kerrison ND, Kinnunen L, Klopp N, Kong A, Kovacs P, Kraft P, Kravic J, Langford C, Leander K, Liang L, Lichtner P, Lindgren CM, Lindholm E, Linneberg A, Liu CT, Lobbens S, Luan J, Lyssenko V, Mannisto S, McLeod O, Meyer J, Mihailov E, Mirza G, Muhleisen TW, Muller-Nurasyid M, Navarro C, Nothen MM, Oskolkov NN, Owen KR, Palli D, Pechlivanis S, Peltonen L, Perry JR, Platou CG, Roden M, Ruderfer D, Rybin D, van der Schouw YT, Sennblad B, Sigurethsson G, Stancakova A, Steinbach G, Storm P, Strauch K, Stringham HM, Sun Q, Thorand B, Tikkanen E, Tonjes A, Trakalo J, Tremoli E, Tuomi T, Wennauer R, Wiltshire S, Wood AR, Zeggini E, Dunham I, Birney E, Pasquali L, Ferrer J, Loos RJ, Dupuis J, Florez JC, Boerwinkle E, Pankow JS, van Duijn C, Sijbrands E, Meigs JB, Hu FB, Thorsteinsdottir U, Stefansson K, Lakka TA, Rauramaa R, Stumvoll M, Pedersen NL, Lind L, Keinanen-Kiukaanniemi SM, Korpi-Hyovalti E, Saaristo TE, Saltevo J, Kuusisto J, Laakso M, Metspalu A, Erbel R, Jocke KH, Moebus S, Ripatti S, Salomaa V, Ingelsson E, Boehm BO, Bergman RN, Collins FS, Mohlke KL, Koistinen H, Tuomilehto J, Hveem K, Njolstad I, Deloukas P, Donnelly PJ, Frayling TM, Hattersley AT, de Faire U, Hamsten A, Illig T, Peters A, Cauchi S, Sladek R, Froguel P, Hansen T, Pedersen O, Morris AD, Palmer CN, Kathiresan S, Melander O, Nilsson PM, Groop LC, Barroso I, Langenberg C, Wareham NJ, O’Callaghan CA, Gloyn AL, Altshuler D, Boehnke M, Teslovich TM, McCarthy MI, Morris AP. (2015) Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nat Genet. 47(12):1415-1425. PMC4666734.
85. O’Neal WK, Gallins P, Pace RG, Dang H, Wolf WE, Jones LC, Guo X, Zhou YH, Madar V, Huang J#, Liang L, Moffatt MF, Cutting GR, Drumm ML, Rommens JM, Strug LJ, Sun W, Stonebraker JR, Wright FA, Knowles MR. (2015) Gene expression in transformed lymphocytes reveals variation in endomembrane and HLA pathways modifying cystic fibrosis pulmonary phenotypes. Am J Hum Genet. 96(2):318-328. PMC4320265.
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88. van der Valk RJ, Kreiner-Moller E, Kooijman MN, Guxens M, Stergiakouli E, Saaf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Korner A, Thiering E, Curtin JA, Myhre R, Huikari V, Joro R, Kerkhof M, Warrington NM, Pitkanen N, Ntalla I, Horikoshi M, Veijola R, Freathy RM, Teo YY, Barton SJ, Evans DM, Kemp JP, St Pourcain B, Ring SM, Davey Smith G, Bergstrom A, Kull I, Hakonarson H, Mentch FD, Bisgaard H, Chawes B, Stokholm J, Waage J, Eriksen P, Sevelsted A, Melbye M, van Duijn CM, Medina-Gomez C, Hofman A, de Jongste JC, Taal HR, Uitterlinden AG, Armstrong LL, Eriksson J, Palotie A, Bustamante M, Estivill X, Gonzalez JR, Llop S, Kiess W, Mahajan A, Flexeder C, Tiesler CM, Murray CS, Simpson A, Magnus P, Sengpiel V, Hartikainen AL, Keinanen-Kiukaanniemi S, Lewin A, Da Silva Couto Alves A, Blakemore AI, Buxton JL, Kaakinen M, Rodriguez A, Sebert S, Vaarasmaki M, Lakka T, Lindi V, Gehring U, Postma DS, Ang W, Newnham JP, Lyytikainen LP, Pahkala K, Raitakari OT, Panoutsopoulou K, Zeggini E, Boomsma DI, Groen-Blokhuis M, Ilonen J, Franke L, Hirschhorn JN, Pers TH, Liang L, Huang J#, Hocher B, Knip M, Saw SM, Holloway JW, Melen E, Grant SF, Feenstra B, Lowe WL, Widen E, Sergeyev E, Grallert H, Custovic A, Jacobsson B, Jarvelin MR, Atalay M, Koppelman GH, Pennell CE, Niinikoski H, Dedoussis GV, McCarthy MI, Frayling TM, Sunyer J, Timpson NJ, Rivadeneira F, Bonnelykke K, Jaddoe VW. (2015) A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet. 24(4):1155-1168. PMC4447786.
89. Rahmioglu N, Macgregor S, Drong AW, Hedman AK, Harris HR, Randall JC, Prokopenko I, International Endogene Consortium (IEC), The GIANT Consortium, Nyholt DR, Morris AP, Montgomery GW, Missmer SA, Lindgren CM, Zondervan KT. (2015) Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci. Hum Mol Genet. 24(4):1185-1199. PMC4576730.
90. Walter S, Glymour MM, Koenen K, Liang L, Tchetgen Tchetgen EJ, Cornelis M, Chang SC, Rewak M, Rimm E, Kawachi I, Kubzansky LD. (2015) Do genetic risk scores for body mass index predict risk of phobic anxiety? Evidence for a shared genetic risk factor. Psychol Med. 45(1):181-191. PMC4387884.
91. Vijai J, Wang Z, Berndt SI, Skibola CF, Slager SL, de Sanjose S, Melbye M, Glimelius B, Bracci PM, Conde L, Birmann BM, Wang SS, Brooks-Wilson AR, Lan Q, de Bakker PI, Vermeulen RC, Portlock C, Ansell SM, Link BK, Riby J, North KE, Gu J, Hjalgrim H, Cozen W, Becker N, Teras LR, Spinelli JJ, Turner J, Zhang Y, Purdue MP, Giles GG, Kelly RS, Zeleniuch-Jacquotte A, Ennas MG, Monnereau A, Bertrand KA, Albanes D, Lightfoot T, Yeager M, Chung CC, Burdett L, Hutchinson A, Lawrence C, Montalvan R, Liang L, Huang J#, Ma B#, Villano DJ, Maria A, Corines M, Thomas T, Novak AJ, Dogan A, Liebow M, Thompson CA, Witzig TE, Habermann TM, Weiner GJ, Smith MT, Holly EA, Jackson RD, Tinker LF, Ye Y, Adami HO, Smedby KE, De Roos AJ, Hartge P, Morton LM, Severson RK, Benavente Y, Boffetta P, Brennan P, Foretova L, Maynadie M, McKay J, Staines A, Diver WR, Vajdic CM, Armstrong BK, Kricker A, Zheng T, Holford TR, Severi G, Vineis P, Ferri GM, Ricco R, Miligi L, Clavel J, Giovannucci E, Kraft P, Virtamo J, Smith A, Kane E, Roman E, Chiu BC, Fraumeni JF, Wu X, Cerhan JR, Offit K, Chanock SJ, Rothman N, Nieters A. (2015) A genome-wide association study of marginal zone lymphoma shows association to the HLA region. Nat Commun. 6(5751. PMC4287989.
92. Aslibekyan S, Demerath EW, Mendelson M, Zhi D, Guan W, Liang L, Sha J, Pankow JS, Liu C, Irvin MR, Fornage M, Hidalgo B, Lin LA, Thibeault KS, Bressler J, Tsai MY, Grove ML, Hopkins PN, Boerwinkle E, Borecki IB, Ordovas JM, Levy D, Tiwari HK, Absher DM, Arnett DK. (2015) Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference. Obesity (Silver Spring). 23(7):1493-1501. PMC4482015.
93. Huang YT, Liang L, Moffatt MF, Cookson WO, Lin X. (2015) iGWAS: Integrative Genome-Wide Association Studies of Genetic and Genomic Data for Disease Susceptibility Using Mediation Analysis. Genet Epidemiol. 39(5):347-356. PMC4544880.
94. Shah S, Bonder MJ, Marioni RE, Zhu Z#, McRae AF, Zhernakova A, Harris SE, Liewald D, Henders AK, Mendelson MM, Liu C, Joehanes R, Liang L, Levy D, Martin NG, Starr JM, Wijmenga C, Wray NR, Yang J, Montgomery GW, Franke L, Deary IJ, Visscher PM. (2015) Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations. Am J Hum Genet. 97(1):75-85. PMC4572498.
95. Wang C#, Zhan X, Liang L, Abecasis GR, Lin X. (2015) Improved ancestry estimation for both genotyping and sequencing data using projection procrustes analysis and genotype imputation. Am J Hum Genet. 96(6):926-937. PMC4457959.
96. Walter S, Kubzansky LD, Koenen KC, Liang L, Tchetgen Tchetgen EJ, Cornelis MC, Chang SC, Rimm E, Kawachi I, Glymour MM. (2015) Revisiting Mendelian randomization studies of the effect of body mass index on depression. Am J Med Genet B Neuropsychiatr Genet. 168b(2):108-115. PMC4387873.
97. He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L^, Gui L, Qi Q, Huang J#, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L. (2015) Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum Mol Genet. 24(6):1791-1800. PMC4351379.
98. Huang J#, Chen J#, Esparza J, Ding J, Elder JT, Abecasis GR, Lee YA, Mark Lathrop G, Moffatt MF, Cookson WO, Liang L*. (2015) eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues. Nat Commun. 6(6821). PMC4929061.
99. Lai PS, Liang L, Cibas ES, Liu AH, Gold DR, Baccarelli A, Phipatanakul W. (2015) Alternate methods of nasal epithelial cell sampling for airway genomic studies. J Allergy Clin Immunol. 136(4):1120-1123.e1124. PMC4600430.

2016

100. Ruiz-Canela M, Toledo E, Clish CB, Hruby A, Liang L, Salas-Salvado J, Razquin C, Corella D, Estruch R, Ros E, Fito M, Gomez-Gracia E, Aros F, Fiol M, Lapetra J, Serra-Majem L, Martinez-Gonzalez MA, Hu FB. (2016) Plasma Branched-Chain Amino Acids and Incident Cardiovascular Disease in the PREDIMED Trial. Clin Chem. 62(4):582-592. PMC4896732.
101. Siiskonen SJ, Zhang M, Li WQ, Liang L, Kraft P, Nijsten T, Han J, Qureshi AA. (2016) A Genome-Wide Association Study of Cutaneous Squamous Cell Carcinoma among European Descendants. Cancer Epidemiol Biomarkers Prev. 25(4):714-720. PMC4873347.
102. Machiela MJ, Lan Q, Slager SL, Vermeulen RC, Teras LR, Camp NJ, Cerhan JR, Spinelli JJ, Wang SS, Nieters A, Vijai J, Yeager M, Wang Z, Ghesquieres H, McKay J, Conde L, de Bakker PI, Cox DG, Burdett L, Monnereau A, Flowers CR, De Roos AJ, Brooks-Wilson AR, Giles GG, Melbye M, Gu J, Jackson RD, Kane E, Purdue MP, Vajdic CM, Albanes D, Kelly RS, Zucca M, Bertrand KA, Zeleniuch-Jacquotte A, Lawrence C, Hutchinson A, Zhi D, Habermann TM, Link BK, Novak AJ, Dogan A, Asmann YW, Liebow M, Thompson CA, Ansell SM, Witzig TE, Tilly H, Haioun C, Molina TJ, Hjalgrim H, Glimelius B, Adami HO, Roos G, Bracci PM, Riby J, Smith MT, Holly EA, Cozen W, Hartge P, Morton LM, Severson RK, Tinker LF, North KE, Becker N, Benavente Y, Boffetta P, Brennan P, Foretova L, Maynadie M, Staines A, Lightfoot T, Crouch S, Smith A, Roman E, Diver WR, Offit K, Zelenetz A, Klein RJ, Villano DJ, Zheng T, Zhang Y, Holford TR, Turner J, Southey MC, Clavel J, Virtamo J, Weinstein S, Riboli E, Vineis P, Kaaks R, Boeing H, Tjonneland A, Angelucci E, Di Lollo S, Rais M, De Vivo I, Giovannucci E, Kraft P, Huang J, Ma B, Ye Y, Chiu BC, Liang L, Park JH, Chung CC, Weisenburger DD, Fraumeni JF, Jr., Salles G, Glenn M, Cannon-Albright L, Curtin K, Wu X, Smedby KE, de Sanjose S, Skibola CF, Berndt SI, Birmann BM, Chanock SJ, Rothman N. (2016) Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes. Hum Mol Genet. 25(8):1663-1676. PMC4854019.
103. Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Muller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stancakova A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, van der Schouw YT, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Jr., Thameem F, Wilson G, Sr., Wong TY, Njolstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jorgensen ME, Jorgensen T, Ladenvall C, Justesen JM, Karajamaki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O’Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvanen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JCN, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Magi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Burtt NP, Mohlke KL, Meitinger T, Groop L, Abecasis G, Florez JC, Scott LJ, Morris AP, Kang HM, Boehnke M, Altshuler D, McCarthy MI. (2016) The genetic architecture of type 2 diabetes. Nature. 536(7614):41-47. PMC5034897.
104. Li X, Cornelis MC, Liang L, Song F, De Vivo I, Giovannucci E, Tang JY, Han J. (2016) A genome-wide analysis of gene-caffeine consumption interaction on basal cell carcinoma. Carcinogenesis. 37(12):1138-1143. PMC5137266.
105. Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, Stergiakouli E, Chesi A, Gaillard R, Feenstra B, Thiering E, Kreiner-Moller E, Mahajan A, Pitkanen N, Joro R, Cavadino A, Huikari V, Franks S, Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimaki T, Curtin JA, Vioque J, Ahluwalia TS, Myhre R, Price TS, Vilor-Tejedor N, Yengo L, Grarup N, Ntalla I, Ang W, Atalay M, Bisgaard H, Blakemore AI, Bonnefond A, Carstensen L, Eriksson J, Flexeder C, Franke L, Geller F, Geserick M, Hartikainen AL, Haworth CM, Hirschhorn JN, Hofman A, Holm JC, Horikoshi M, Hottenga JJ, Huang J#, Kadarmideen HN, Kahonen M, Kiess W, Lakka HM, Lakka TA, Lewin AM, Liang L, Lyytikainen LP, Ma B, Magnus P, McCormack SE, McMahon G, Mentch FD, Middeldorp CM, Murray CS, Pahkala K, Pers TH, Pfaffle R, Postma DS, Power C, Simpson A, Sengpiel V, Tiesler CM, Torrent M, Uitterlinden AG, van Meurs JB, Vinding R, Waage J, Wardle J, Zeggini E, Zemel BS, Dedoussis GV, Pedersen O, Froguel P, Sunyer J, Plomin R, Jacobsson B, Hansen T, Gonzalez JR, Custovic A, Raitakari OT, Pennell CE, Widen E, Boomsma DI, Koppelman GH, Sebert S, Jarvelin MR, Hypponen E, McCarthy MI, Lindi V, Harri N, Korner A, Bonnelykke K, Heinrich J, Melbye M, Rivadeneira F, Hakonarson H, Ring SM, Smith GD, Sorensen TI, Timpson NJ, Grant SF, Jaddoe VW. (2016) Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet. 25(2):389-403. PMC4854022.
106. Zhu X, Li J#, Deng S, Yu K, Liu X, Deng Q, Sun H, Zhang X, He M, Guo H, Chen W, Yuan J, Zhang B, Kuang D, He X, Bai Y, Han X, Liu B, Li X, Yang L, Jiang H, Zhang Y, Hu J, Cheng L, Luo X, Mei W, Zhou Z, Sun S, Zhang L, Liu C, Guo Y#, Zhang Z, Hu FB, Liang L, Wu T. (2016) Genome-Wide Analysis of DNA Methylation and Cigarette Smoking in a Chinese Population. Environ Health Perspect. 124(7):966-973. PMC4937856.
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108. Berndt SI, Camp NJ, Skibola CF, Vijai J, Wang Z, Gu J, Nieters A, Kelly RS, Smedby KE, Monnereau A, Cozen W, Cox A, Wang SS, Lan Q, Teras LR, Machado M, Yeager M, Brooks-Wilson AR, Hartge P, Purdue MP, Birmann BM, Vajdic CM, Cocco P, Zhang Y, Giles GG, Zeleniuch-Jacquotte A, Lawrence C, Montalvan R, Burdett L, Hutchinson A, Ye Y, Call TG, Shanafelt TD, Novak AJ, Kay NE, Liebow M, Cunningham JM, Allmer C, Hjalgrim H, Adami HO, Melbye M, Glimelius B, Chang ET, Glenn M, Curtin K, Cannon-Albright LA, Diver WR, Link BK, Weiner GJ, Conde L, Bracci PM, Riby J, Arnett DK, Zhi D, Leach JM, Holly EA, Jackson RD, Tinker LF, Benavente Y, Sala N, Casabonne D, Becker N, Boffetta P, Brennan P, Foretova L, Maynadie M, McKay J, Staines A, Chaffee KG, Achenbach SJ, Vachon CM, Goldin LR, Strom SS, Leis JF, Weinberg JB, Caporaso NE, Norman AD, De Roos AJ, Morton LM, Severson RK, Riboli E, Vineis P, Kaaks R, Masala G, Weiderpass E, Chirlaque MD, Vermeulen RCH, Travis RC, Southey MC, Milne RL, Albanes D, Virtamo J, Weinstein S, Clavel J, Zheng T, Holford TR, Villano DJ, Maria A, Spinelli JJ, Gascoyne RD, Connors JM, Bertrand KA, Giovannucci E, Kraft P, Kricker A, Turner J, Ennas MG, Ferri GM, Miligi L, Liang L, Ma B#, Huang J#, Crouch S, Park JH, Chatterjee N, North KE, Snowden JA, Wright J, Fraumeni JF, Offit K, Wu X, de Sanjose S, Cerhan JR, Chanock SJ, Rothman N, Slager SL. (2016) Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. Nat Commun. 7(10933. PMC4786871.
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113. Sarnowski C, Laprise C, Malerba G, Moffatt MF, Dizier MH, Morin A, Vincent QB, Rohde K, Esparza-Gordillo J, Margaritte-Jeannin P, Liang L, Lee YA, Bousquet J, Siroux V, Pignatti PF, Cookson WO, Lathrop M, Pastinen T, Demenais F, Bouzigon E. (2016) DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis. J Allergy Clin Immunol. 138(3):748-753. PMID: 27038909.
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120. Lindstrom S, Loomis S, Turman C, Huang H, Huang J#, Aschard H, Chan AT, Choi H, Cornelis M, Curhan G, De Vivo I, Eliassen AH, Fuchs C, Gaziano M, Hankinson SE, Hu F, Jensen M, Kang JH, Kabrhel C, Liang L, Pasquale LR, Rimm E, Stampfer MJ, Tamimi RM, Tworoger SS, Wiggs JL, Hunter DJ, Kraft P. (2017) A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts. PLoS One. 12(3):e0173997. PMC5354293.
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137. Li J#, Zhu X, Yu K, Jiang H, Zhang Y, Deng S, Cheng L, Liu X, Zhong J, Zhang X, He M, Chen W, Yuan J, Gao M, Bai Y, Han X, Liu B, Luo X, Mei W, He X, Sun S, Zhang L, Zeng H, Sun H, Liu C, Guo Y#, Zhang B, Zhang Z, Huang J, Pan A, Yuan Y, Angileri F, Ming B, Zheng F, Zeng Q, Mao X, Peng Y, Mao Y, He P, Wang QK, Qi L, Hu FB, Liang L*, Wu T. (2017) Genome-Wide Analysis of DNA Methylation and Acute Coronary Syndrome. Circ Res. 120(11):1754-1767. PMID: 28348007.
138. Rahman ML, Valeri L, Kile ML, Mazumdar M, Mostofa G, Qamruzzaman Q, Rahman M, Baccarelli A, Liang L, Hauser R, Christiani DC. (2017) Investigating causal relation between prenatal arsenic exposure and birthweight: Are smaller infants more susceptible? Environ Int. 108(32-40. PMC5623127.
139. Scott RA, Scott LJ, Magi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, Thorleifsson G, Qi L, Van Zuydam NR, Mahajan A, Chen H, Almgren P, Voight BF, Grallert H, Muller-Nurasyid M, Ried JS, Rayner NW, Robertson N, Karssen LC, van Leeuwen EM, Willems SM, Fuchsberger C, Kwan P, Teslovich TM, Chanda P, Li M, Lu Y, Dina C, Thuillier D, Yengo L, Jiang L, Sparso T, Kestler HA, Chheda H, Eisele L, Gustafsson S, Franberg M, Strawbridge RJ, Benediktsson R, Hreidarsson AB, Kong A, Sigurethsson G, Kerrison ND, Luan J, Liang L, Meitinger T, Roden M, Thorand B, Esko T, Mihailov E, Fox C, Liu CT, Rybin D, Isomaa B, Lyssenko V, Tuomi T, Couper DJ, Pankow JS, Grarup N, Have CT, Jorgensen ME, Jorgensen T, Linneberg A, Cornelis MC, van Dam RM, Hunter DJ, Kraft P, Sun Q, Edkins S, Owen KR, Perry JRB, Wood AR, Zeggini E, Tajes-Fernandes J, Abecasis GR, Bonnycastle LL, Chines PS, Stringham HM, Koistinen HA, Kinnunen L, Sennblad B, Muhleisen TW, Nothen MM, Pechlivanis S, Baldassarre D, Gertow K, Humphries SE, Tremoli E, Klopp N, Meyer J, Steinbach G, Wennauer R, Eriksson JG, Mnnisto S, Peltonen L, Tikkanen E, Charpentier G, Eury E, Lobbens S, Gigante B, Leander K, McLeod O, Bottinger EP, Gottesman O, Ruderfer D, Bluher M, Kovacs P, Tonjes A, Maruthur NM, Scapoli C, Erbel R, Jockel KH, Moebus S, de Faire U, Hamsten A, Stumvoll M, Deloukas P, Donnelly PJ, Frayling TM, Hattersley AT, Ripatti S, Salomaa V, Pedersen NL, Boehm BO, Bergman RN, Collins FS, Mohlke KL, Tuomilehto J, Hansen T, Pedersen O, Barroso I, Lannfelt L, Ingelsson E, Lind L, Lindgren CM, Cauchi S, Froguel P, Loos RJF, Balkau B, Boeing H, Franks PW, Barricarte Gurrea A, Palli D, van der Schouw YT, Altshuler D, Groop LC, Langenberg C, Wareham NJ, Sijbrands E, van Duijn CM, Florez JC, Meigs JB, Boerwinkle E, Gieger C, Strauch K, Metspalu A, Morris AD, Palmer CNA, Hu FB, Thorsteinsdottir U, Stefansson K, Dupuis J, Morris AP, Boehnke M, McCarthy MI, Prokopenko I. (2017) An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. 66(11):2888-2902. PMC5652602.
140. Chu AY, Tin A, Schlosser P, Ko YA, Qiu C, Yao C, Joehanes R, Grams ME, Liang L, Gluck CA, Liu C, Coresh J, Hwang SJ, Levy D, Boerwinkle E, Pankow JS, Yang Q, Fornage M, Fox CS, Susztak K, Kottgen A. (2017) Epigenome-wide association studies identify DNA methylation associated with kidney function. Nat Commun. 8(1):1286. PMC5668367.
141. Feng YA#, Cho K, Lindstrom S, Kraft P, Cormack J, Liang L*, Driver JA. (2017) Investigating the genetic relationship between Alzheimer’s disease and cancer using GWAS summary statistics. Hum Genet. 136(10):1341-1351. PMC5693762.
142. Toledo E, Wang DD, Ruiz-Canela M, Clish CB, Razquin C, Zheng Y, Guasch-Ferre M, Hruby A, Corella D, Gomez-Gracia E, Fiol M, Estruch R, Ros E, Lapetra J, Fito M, Aros F, Serra-Majem L, Liang L, Salas-Salvado J, Hu FB, Martinez-Gonzalez MA. (2017) Plasma lipidomic profiles and cardiovascular events in a randomized intervention trial with the Mediterranean diet. Am J Clin Nutr. 106(4):973-983. PMC5611779.
143. Yao Y#, Xu M, Liang L^, Zhang H, Xu R, Feng Q, Feng L, Luo B, Zeng YX. (2017) Genome-wide analysis of Epstein-Barr virus identifies variants and genes associated with gastric carcinoma and population structure. Tumour Biol. 39(10):1010428317714195. PMID: 29034771.
144. Ye W, Chang ET, Liu Z, Liu Q, Cai Y, Zhang Z, Chen G, Huang QH, Xie SH, Cao SM, Shao JY, Jia WH, Zheng Y, Liao J, Chen Y, Lin L, Liang L, Ernberg I, Vaughan TL, Huang G, Zeng Y, Zeng YX, Adami HO. (2017) Development of a population-based cancer case-control study in southern china. Oncotarget. 8(50):87073-87085. PMC5675616.
145. Guasch-Ferre M, Hu FB, Ruiz-Canela M, Bullo M, Toledo E, Wang DD, Corella D, Gomez-Gracia E, Fiol M, Estruch R, Lapetra J, Fito M, Aros F, Serra-Majem L, Ros E, Dennis C, Liang L, Clish CB, Martinez-Gonzalez MA, Salas-Salvado J. (2017) Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study. J Am Heart Assoc. 6(11):PMC5721752.
146. Phipatanakul W, Koutrakis P, Coull BA, Kang CM, Wolfson JM, Ferguson ST, Petty CR, Samnaliev M, Cunningham A, Sheehan WJ, Gaffin JM, Baxi SN, Lai PS, Permaul P, Liang L, Thorne PS, Adamkiewicz G, Brennan KJ, Baccarelli AA, Gold DR. (2017) The School Inner-City Asthma Intervention Study: Design, rationale, methods, and lessons learned. Contemp Clin Trials. 60(14-23. PMC5557648.
147. Ruiz-Canela M, Hruby A, Clish CB, Liang L, Martinez-Gonzalez MA, Hu FB. (2017) Comprehensive Metabolomic Profiling and Incident Cardiovascular Disease: A Systematic Review. J Am Heart Assoc. 6(10):PMC5721826.

2018

148. Rahman ML, Liang L, Valeri L, Su L, Zhu Z#, Gao S, Mostofa G, Qamruzzaman Q, Hauser R, Baccarelli A, Christiani DC. (2018) Regulation of birthweight by placenta-derived miRNAs: evidence from an arsenic-exposed birth cohort in Bangladesh. Epigenetics. 13(6):573-590. PMC6140906.
149. Wang F, Sun L, Sun Q, Liang L, Gao X, Li R, Pan A, Li H, Deng Y, Hu FB, Wu J, Zeng R, Lin X. (2018) Associations of Plasma Amino Acid and Acylcarnitine Profiles with Incident Reduced Glomerular Filtration Rate. Clin J Am Soc Nephrol. 13(4):560-568. PMC5969460.
150. Lin X, Chan KK, Huang YT, Luo XI, Liang L, Wilson J, Correa A, Levy D, Liu S. (2018) Genetic Determinants for Leisure-Time Physical Activity. Med Sci Sports Exerc. 50(8):1620-1628. PMC6087666.
151. Tobias DK, Clish C, Mora S, Li J#, Liang L, Hu FB, Manson JE, Zhang C. (2018) Dietary Intakes and Circulating Concentrations of Branched-Chain Amino Acids in Relation to Incident Type 2 Diabetes Risk Among High-Risk Women with a History of Gestational Diabetes Mellitus. Clin Chem. 64(8):1203-1210. PMC6434682.
152. Yu E, Papandreou C, Ruiz-Canela M, Guasch-Ferre M, Clish CB, Dennis C, Liang L, Corella D, Fito M, Razquin C, Lapetra J, Estruch R, Ros E, Cofan M, Aros F, Toledo E, Serra-Majem L, Sorli JV, Hu FB, Martinez-Gonzalez MA, Salas-Salvado J. (2018) Association of Tryptophan Metabolites with Incident Type 2 Diabetes in the PREDIMED Trial: A Case-Cohort Study. Clin Chem. 64(8):1211-1220. PMC6218929.
153. Razquin C, Toledo E, Clish CB, Ruiz-Canela M, Dennis C, Corella D, Papandreou C, Ros E, Estruch R, Guasch-Ferre M, Gomez-Gracia E, Fito M, Yu E, Lapetra J, Wang D, Romaguera D, Liang L, Alonso-Gomez A, Deik A, Bullo M, Serra-Majem L, Salas-Salvado J, Hu FB, Martinez-Gonzalez MA. (2018) Plasma Lipidomic Profiling and Risk of Type 2 Diabetes in the PREDIMED Trial. Diabetes Care. 41(12):2617-2624. PMC6245212.
154. Wang DD, Zheng Y, Toledo E, Razquin C, Ruiz-Canela M, Guasch-Ferre M, Yu E, Corella D, Gomez-Gracia E, Fiol M, Estruch R, Ros E, Lapetra J, Fito M, Aros F, Serra-Majem L, Clish CB, Salas-Salvado J, Liang L, Martinez-Gonzalez MA, Hu FB. (2018) Lipid metabolic networks, Mediterranean diet and cardiovascular disease in the PREDIMED trial. Int J Epidemiol. 47(6):1830-1845. PMC6280948.
155. Liu G, Dhana K, Furtado JD, Rood J, Zong G, Liang L, Qi L, Bray GA, DeJonge L, Coull B, Grandjean P, Sun Q. (2018) Perfluoroalkyl substances and changes in body weight and resting metabolic rate in response to weight-loss diets: A prospective study. PLoS Med. 15(2):e1002502. PMC5810983.
156. Razquin C, Liang L, Toledo E, Clish CB, Ruiz-Canela M, Zheng Y, Wang DD, Corella D, Castaner O, Ros E, Aros F, Gomez-Gracia E, Fiol M, Santos-Lozano JM, Guasch-Ferre M, Serra-Majem L, Sala-Vila A, Buil-Cosiales P, Bullo M, Fito M, Portoles O, Estruch R, Salas-Salvado J, Hu FB, Martinez-Gonzalez MA. (2018) Plasma lipidome patterns associated with cardiovascular risk in the PREDIMED trial: A case-cohort study. Int J Cardiol. 253(126-132. PMC5759348.
157. Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmuller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bonnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA, Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliovaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kahonen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimaki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, Loth DW, Manichaikul A, Marenholz I, Martinez FJ, Matheson MC, Mathias RA, Matsumoto K, Mbarek H, McArdle WL, Melbye M, Melen E, Meyers D, Michel S, Mohamdi H, Musk AW, Myers RA, Nieuwenhuis MAE, Noguchi E, O’Connor GT, Ogorodova LM, Palmer CD, Palotie A, Park JE, Pennell CE, Pershagen G, Polonikov A, Postma DS, Probst-Hensch N, Puzyrev VP, Raby BA, Raitakari OT, Ramasamy A, Rich SS, Robertson CF, Romieu I, Salam MT, Salomaa V, Schlunssen V, Scott R, Selivanova PA, Sigsgaard T, Simpson A, Siroux V, Smith LJ, Solodilova M, Standl M, Stefansson K, Strachan DP, Stricker BH, Takahashi A, Thompson PJ, Thorleifsson G, Thorsteinsdottir U, Tiesler CMT, Torgerson DG, Tsunoda T, Uitterlinden AG, van der Valk RJP, Vaysse A, Vedantam S, von Berg A, von Mutius E, Vonk JM, Waage J, Wareham NJ, Weiss ST, White WB, Wickman M, Widen E, Willemsen G, Williams LK, Wouters IM, Yang JJ, Zhao JH, Moffatt MF, Ober C, Nicolae DL. (2018) Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 50(1):42-53. PMC5901974.
158. Ruiz-Canela M, Guasch-Ferre M, Toledo E, Clish CB, Razquin C, Liang L, Wang DD, Corella D, Estruch R, Hernaez A, Yu E, Gomez-Gracia E, Zheng Y, Aros F, Romaguera D, Dennis C, Ros E, Lapetra J, Serra-Majem L, Papandreou C, Portoles O, Fito M, Salas-Salvado J, Hu FB, Martinez-Gonzalez MA. (2018) Plasma branched chain/aromatic amino acids, enriched Mediterranean diet and risk of type 2 diabetes: case-cohort study within the PREDIMED Trial. Diabetologia. 61(7):1560-1571. PMC5988977.
159. Papandreou C, Bullo M, Zheng Y, Ruiz-Canela M, Yu E, Guasch-Ferre M, Toledo E, Clish C, Corella D, Estruch R, Ros E, Fito M, Aros F, Fiol M, Lapetra J, Serra-Majem L, Gomez-Gracia E, Liang L, Fragkiadakis GA, Razquin C, Hu FB, Salas-Salvado J. (2018) Plasma trimethylamine-N-oxide and related metabolites are associated with type 2 diabetes risk in the Prevencion con Dieta Mediterranea (PREDIMED) trial. Am J Clin Nutr. 108(1):163-173. PMID: 29982310.
160. Li J#, Zhu X, Yu K, Jiang H, Zhang Y, Wang B, Liu X, Deng S, Hu J, Deng Q, Sun H, Guo H, Zhang X, Chen W, Yuan J, He M, Bai Y, Han X, Liu B, Liu C, Guo Y#, Zhang B, Zhang Z, Hu FB, Gao W, Li L, Lathrop M, Laprise C, Liang L*, Wu T. (2018) Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging. Environ Health Perspect. 126(6):067005. PMC6108582.
161. Zhu Z#, Lee PH, Chaffin MD#, Chung W#, Loh PR, Lu Q, Christiani DC, Liang L*. (2018) A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. Nat Genet. 50(6):857-864. PMC5980765.
162. Rahman ML, Kile ML, Rodrigues EG, Valeri L, Raj A, Mazumdar M, Mostofa G, Quamruzzaman Q, Rahman M, Hauser R, Baccarelli A, Liang L, Christiani DC. (2018) Prenatal arsenic exposure, child marriage, and pregnancy weight gain: Associations with preterm birth in Bangladesh. Environ Int. 112(23-32. PMC6530570.
163. Tabung FK, Giovannucci EL, Giulianini F, Liang L, Chandler PD, Balasubramanian R, Manson JE, Cespedes Feliciano EM, Hayden KM, Van Horn L, Rexrode KM. (2018) An Empirical Dietary Inflammatory Pattern Score Is Associated with Circulating Inflammatory Biomarkers in a Multi-Ethnic Population of Postmenopausal Women in the United States. J Nutr. 148(5):771-780. PMC5972616.
164. Martinez RM, Liang L, Racowsky C, Dioni L, Mansur A, Adir M, Bollati V, Baccarelli AA, Hauser R, Machtinger R. (2018) Extracellular microRNAs profile in human follicular fluid and IVF outcomes. Sci Rep. 8(1):17036. PMC6242846.

2019

165. Ma B#, Allard C, Bouchard L, Perron P, Mittleman MA, Hivert MF, Liang L*. (2019) Locus-specific DNA methylation prediction in cord blood and placenta. Epigenetics. 14(4):405-420. PMC6557556.
166. Zhu Z#, Wang X, Li X, Lin Y#, Shen S, Liu CL, Hobbs BD, Hasegawa K, Liang L, Boezen HM, Camargo CA, Jr., Cho MH, Christiani DC. (2019) Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross- trait analysis. Respir Res. 20(1):64. PMC6444755.
167. Bjornevik K, Zhang Z, O’Reilly EJ, Berry JD, Clish CB, Deik A, Jeanfavre S, Kato I, Kelly RS, Kolonel LN, Liang L, Marchand LL, McCullough ML, Paganoni S, Pierce KA, Schwarzschild MA, Shadyab AH, Wactawski-Wende J, Wang DD, Wang Y, Manson JE, Ascherio A. (2019) Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis. Neurology. 92(18):e2089-e2100. PMC6512888.
168. Martinez RM, Baccarelli AA, Liang L, Dioni L, Mansur A, Adir M, Bollati V, Racowsky C, Hauser R, Machtinger R. (2019) Body mass index in relation to extracellular vesicle-linked microRNAs in human follicular fluid. Fertil Steril. 112(2):387-396.e383. PMC6663626.
169. Hu Y, Liu G, Rood J, Liang L, Bray GA, de Jonge L, Coull B, Furtado JD, Qi L, Grandjean P, Sun Q. (2019) Perfluoroalkyl substances and changes in bone mineral density: A prospective analysis in the POUNDS-LOST study. Environ Res. 179(Pt A):108775. PMC6905427.
170. Zhu Z#, Zhu X, Liu CL, Shi H, Shen S, Yang Y, Hasegawa K, Camargo CA, Jr., Liang L*. (2019) Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. European Respiratory Journal. 54(6):PMID: 31619474.
171. Martinez RM, Hauser R, Liang L, Mansur A, Adir M, Dioni L, Racowsky C, Bollati V, Baccarelli AA, Machtinger R. (2019) Urinary concentrations of phenols and phthalate metabolites reflect extracellular vesicle microRNA expression in follicular fluid. Environ Int. 123(20-28. PMC6343661.
172. Yu E, Ruiz-Canela M, Razquin C, Guasch-Ferre M, Toledo E, Wang DD, Papandreou C, Dennis C, Clish C, Liang L, Bullo M, Corella D, Fito M, Gutierrez-Bedmar M, Lapetra J, Estruch R, Ros E, Cofan M, Aros F, Romaguera D, Serra-Majem L, Sorli JV, Salas-Salvado J, Hu FB, Martinez-Gonzalez MA. (2019) Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial. Diabetes Obes Metab. 21(2):397-401. PMC6329637.
173. Chung W#, Chen J#, Turman C, Lindstrom S, Zhu Z#, Loh PR, Kraft P, Liang L*. (2019) Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes. Nat Commun. 10(1):569. PMC6361917.
174. Papandreou C, Li J#, Liang L, Bullo M, Zheng Y, Ruiz-Canela M, Yu E, Guasch-Ferre M, Razquin C, Clish C, Corella D, Estruch R, Ros E, Fito M, Aros F, Serra-Majem L, Rosique N, Martinez-Gonzalez MA, Hu FB, Salas-Salvado J. (2019) Metabolites related to purine catabolism and risk of type 2 diabetes incidence; modifying effects of the TCF7L2-rs7903146 polymorphism. Sci Rep. 9(1):2892. PMC6393542.
175. Xiao Y, Yuan Y, Liu Y, Yu Y, Jia N, Zhou L, Wang H, Huang S, Zhang Y, Yang H, Li X, Hu FB, Liang L, Pan A, Zhang X, He M, Cheng J, Wu T. (2019) Circulating Multiple Metals and Incident Stroke in Chinese Adults. Stroke. 50(7):1661-1668. PMC6594729.
176. Lains I, Chung W#, Kelly RS, Gil J, Marques M, Barreto P, Murta JN, Kim IK, Vavvas DG, Miller JB, Silva R, Lasky-Su J, Liang L*, Miller JW*, Husain D*. (2019) Human Plasma Metabolomics in Age-Related Macular Degeneration: Meta- Analysis of Two Cohorts. Metabolites. 9(7):PMC6680405.
177. Cardenas A, Sordillo JE, Rifas-Shiman SL, Chung W#, Liang L, Coull BA, Hivert MF, Lai PS, Forno E, Celedon JC, Litonjua AA, Brennan KJ, DeMeo DL, Baccarelli AA, Oken E, Gold DR. (2019) The nasal methylome as a biomarker of asthma and airway inflammation in children. Nat Commun. 10(1):3095. PMC6625976.
178. Tabung FK, Liang L, Huang T, Balasubramanian R, Zhao Y, Chandler PD, Manson JE, Cespedes Feliciano EM, Hayden KM, Van Horn L, Clish CB, Giovannucci EL, Rexrode KM. (2019) Identifying metabolomic profiles of inflammatory diets in postmenopausal women. Clin Nutr. PMC6918009.
179. Tabung FK, Balasubramanian R, Liang L, Clinton SK, Cespedes Feliciano EM, Manson JE, Van Horn L, Wactawski-Wende J, Clish CB, Giovannucci EL, Rexrode KM. (2019) Identifying Metabolomic Profiles of Insulinemic Dietary Patterns. Metabolites. 9(6):PMC6630814.
180. Zhu Z#, Lin Y#, Li X, Driver JA, Liang L*. (2019) Shared genetic architecture between metabolic traits and Alzheimer’s disease: a large-scale genome-wide cross-trait analysis. Hum Genet. 138(3):271-285. PMID: 30805717.
181. Papandreou C, Bullo M, Ruiz-Canela M, Dennis C, Deik A, Wang D, Guasch-Ferre M, Yu E, Razquin C, Corella D, Estruch R, Ros E, Fito M, Fiol M, Liang L, Hernandez-Alonso P, Clish CB, Martinez-Gonzalez MA, Hu FB, Salas-Salvado J. (2019) Plasma metabolites predict both insulin resistance and incident type 2 diabetes: a metabolomics approach within the Prevencion con Dieta Mediterranea (PREDIMED) study. Am J Clin Nutr. 109(3):626-634. PMID: 30796776.
182. Chaffin MD#, Cao L#, Deik AA, Clish CB, Hu FB, Martinez-Gonzalez MA, Razquin C, Bullo M, Corella D, Gomez-Gracia E, Fiol M, Estruch R, Lapetra J, Fito M, Aros F, Serra-Majem L, Ros E, Liang L*. (2019) MetProc: Separating Measurement Artifacts from True Metabolites in an Untargeted Metabolomics Experiment. J Proteome Res. 18(3):1446-1450. PMID: 30562035.
183. Ma J, Nano J, Ding J, Zheng Y, Hennein R, Liu C, Speliotes EK, Huan T, Song C, Mendelson MM, Joehanes R, Long MT, Liang L, Smith JA, Reynolds LM, Ghanbari M, Muka T, van Meurs JBJ, Alferink LJM, Franco OH, Dehghan A, Ratliff S, Zhao W, Bielak L, Kardia SLR, Peyser PA, Ning H, VanWagner LB, Lloyd-Jones DM, Carr JJ, Greenland P, Lichtenstein AH, Hu FB, Liu Y, Hou L, Darwish Murad S, Levy D. (2019) A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease. Diabetes. 68(5):1073-1083. PMC6477898.
184. Guasch-Ferre M, Ruiz-Canela M, Li J#, Zheng Y, Bullo M, Wang DD, Toledo E, Clish C, Corella D, Estruch R, Ros E, Fito M, Aros F, Fiol M, Lapetra J, Serra-Majem L, Liang L, Papandreou C, Dennis C, Martinez-Gonzalez MA, Hu FB, Salas-Salvado J. (2019) Plasma Acylcarnitines and Risk of Type 2 Diabetes in a Mediterranean Population at High Cardiovascular Risk. J Clin Endocrinol Metab. 104(5):1508-1519. PMC6435097.
185. Papandreou C, Hernandez-Alonso P, Bullo M, Ruiz-Canela M, Yu E, Guasch-Ferre M, Toledo E, Dennis C, Deik A, Clish C, Razquin C, Corella D, Estruch R, Ros E, Fito M, Aros F, Fiol M, Lapetra J, Ruano C, Liang L, Martinez-Gonzalez MA, Hu FB, Salas-Salvado J. (2019) Plasma Metabolites Associated with Coffee Consumption: A Metabolomic Approach within the PREDIMED Study. Nutrients. 11(5):PMC6566346.
186. Stewart CJ, Mansbach JM, Ajami NJ, Petrosino JF, Zhu Z#, Liang L, Camargo CA, Hasegawa K. (2019) Serum Metabolome Is Associated With the Nasopharyngeal Microbiota and Disease Severity Among Infants With Bronchiolitis. J Infect Dis. 219(12):2005-2014. PMC6534192.
187. Razquin C, Ruiz-Canela M, Clish CB, Li J#, Toledo E, Dennis C, Liang L, Salas-Huetos A, Pierce KA, Guasch-Ferre M, Corella D, Ros E, Estruch R, Gomez-Gracia E, Fito M, Lapetra J, Romaguera D, Alonso-Gomez A, Serra-Majem L, Salas-Salvado J, Hu FB, Martinez-Gonzalez MA. (2019) Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case- cohort studies. Cardiovasc Diabetol. 18(1):151. PMC6852717.
188. Liu X, Zheng Y, Guasch-Ferre M, Ruiz-Canela M, Toledo E, Clish C, Liang L, Razquin C, Corella D, Estruch R, Fito M, Gomez-Gracia E, Aros F, Ros E, Lapetra J, Fiol M, Serra-Majem L, Papandreou C, Martinez-Gonzalez MA, Hu FB, Salas-Salvado J. (2019) High plasma glutamate and low glutamine-to-glutamate ratio are associated with type 2 diabetes: Case-cohort study within the PREDIMED trial. Nutr Metab Cardiovasc Dis. 29(10):1040-1049. PMID: 31377179.
189. Wang G, Sun Q, Liang L^, Clash C, Zhang C, Hong X, Ji Y, Radovick S, Pearson C, Bartell TR, Zuckerman B, Cheng TL, Hu FB, Wang X. (2019) Inter-generational link of obesity in term and preterm births: role of maternal plasma acylcarnitines. Int J Obes (Lond). 43(10):1967-1977. PMID: 31332276.
190. Guo Y#, Chung W#, Zhu Z#, Shan Z, Li J#, Liu S, Liang L*. (2019) Genome-Wide Assessment for Resting Heart Rate and Shared Genetics With Cardiometabolic Traits and Type 2 Diabetes. J Am Coll Cardiol. 74(17):2162-2174. PMID: 31648709. (The JACC editorial introducing our study PMID: 32357245, Patricia B. Munroe, Julia Ramírez and Stefan van Duijvenboden. Resting Heart Rate and Type 2 Diabetes: A Complex Relationship in Need of Greater Understanding)
191. Hernandez-Alonso P, Papandreou C, Bullo M, Ruiz-Canela M, Dennis C, Deik A, Wang DD, Guasch-Ferre M, Yu E, Toledo E, Razquin C, Corella D, Estruch R, Ros E, Fito M, Aros F, Fiol M, Serra-Majem L, Liang L, Clish CB, Martinez-Gonzalez MA, Hu FB, Salas-Salvado J. (2019) Plasma Metabolites Associated with Frequent Red Wine Consumption: A Metabolomics Approach within the PREDIMED Study. Mol Nutr Food Res. 63(17):e1900140. PMC6771435.
192. Hong X, Liang L, Sun Q, Keet CA, Tsai HJ, Ji Y, Wang G, Ji H, Clish C, Pearson C, Wang Y, Wood RA, Hu FB, Wang X. (2019) Maternal triacylglycerol signature and risk of food allergy in offspring. J Allergy Clin Immunol. 144(3):729-737. PMC6941352.
193. Huan T, Joehanes R, Song C, Peng F, Guo Y#, Mendelson M, Yao C, Liu C, Ma J, Richard M, Agha G, Guan W, Almli LM, Conneely KN, Keefe J, Hwang SJ, Johnson AD, Fornage M, Liang L*, Levy D. (2019) Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease. Nat Commun. 10(1):4267. PMC6753136.

2020

194. Zhu Z#, Guo Y#, Shi H, Liu CL, Panganiban RA, Chung W#, O’Connor LJ, Himes BE, Gazal S, Hasegawa K, Camargo CA, Jr., Qi L, Moffatt MF, Hu FB, Lu Q, Cookson WOC, Liang L*. (2020) Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank. J Allergy Clin Immunol. 145(2):537-549. PMC7010560. (The JACI editorial introducing our study PMID: 31812573, Raquel Granell, Santiago Rodriguez. Confirmed causal effect of obesity on asthma and new insights on potential underlying shared genetic mechanisms)
195. Long P, Liu X, Li J#, He S, Chen H, Yuan Y, Qiu G, Yu K, Liu K, Jiang J, Yang H, Xu C, Zhang X, He M, Guo H, Liang L, Hu FB, Wu T, Pan A. (2020) Circulating folate concentrations and risk of coronary artery disease: a prospective cohort study in Chinese adults and a Mendelian randomization analysis. Am J Clin Nutr. 2020 Mar 1;111(3):635-643. doi: 10.1093/ajcn/nqz314.PMID: 31927564
196. Liu G, Zhang B, Hu Y, Rood J, Liang L, Qi L, Bray GA, DeJonge L, Coull B, Grandjean P, Furtado JD, Sun Q. (2020) Associations of Perfluoroalkyl substances with blood lipids and Apolipoproteins in lipoprotein subspecies: the POUNDS-lost study. Environ Health. 2020 Jan 13;19(1):5. doi: 10.1186/s12940-020-0561-8.PMID: 31931806
197. Yu K, Lv J, Qiu G, Yu C, Guo Y, Bian Z, Yang L, Chen Y, Wang C, Pan A, Liang L, Hu FB, Chen Z, Li L, Wu T; China Kadoorie Biobank Study. (2020) Cooking fuels and risk of all-cause and cardiopulmonary mortality in urban China: a prospective cohort study. Lancet Glob Health.2020 Mar;8(3):e430-e439. doi: 10.1016/S2214-109X(19)30525-X. Epub 2020 Jan 20.PMID: 31972151
198. Roh M, Shin HJ, Laíns I, Providência J, Caseiro-Alves M, Barreto P, Vavvas DG, Miller JB, Kim IK, Gaziano JM, Liang L, Silva R, Miller JW, Husain D. (2020) Higher Intake of Polyunsaturated Fatty Acid and Monounsaturated Fatty Acid is Inversely Associated With AMD. Invest Ophthalmol Vis Sci. 2020 Feb 7;61(2):20.
199. Guasch-Ferré M, Santos JL, Martínez-González MA, Clish CB, Razquin C, Wang D, Liang L, Li J#, Dennis C, Corella D, Muñoz-Bravo C, Romaguera D, Estruch R, Santos-Lozano JM, Castañer O, Alonso-Gómez A, Serra-Majem L, Ros E, Canudas S, Asensio EM, Fitó M, Pierce K, Martínez JA, Salas-Salvadó J, Toledo E, Hu FB, Ruiz-Canela M. (2020) Glycolysis/gluconeogenesis- and tricarboxylic acid cycle-related metabolites, Mediterranean diet, and type 2 diabetes. Am J Clin Nutr. 2020 Apr 1;111(4):835-844. doi: 10.1093/ajcn/nqaa016.PMID: 32060497
200. Li X, Kraft P, De Vivo I, Giovannucci E, Liang L, Nan H.J (2020) Height, nevus count, and risk of cutaneous malignant melanoma: results from two large cohorts of US women. Am Acad Dermatol. 2020 May 3:S0190-9622(20)30783-0. doi: 10.1016/j.jaad.2020.04.158. Online ahead of print.PMID: 32376423
201. Hernández-Alonso P, Becerra-Tomás N, Papandreou C, Bulló M, Guasch-Ferré M, Toledo E, Ruiz-Canela M, Clish CB, Corella D, Dennis C, Deik A, Wang DD, Razquin C, Drouin-Chartier JP, Estruch R, Ros E, Fitó M, Arós F, Fiol M, Serra-Majem L, Liang L, Martínez-González MA, Hu FB, Salas-Salvadó J. (2020) Plasma Metabolomics Profiles are Associated with the Amount and Source of Protein Intake: A Metabolomics Approach within the PREDIMED Study. Mol Nutr Food Res. 2020 May 7:e2000178. doi: 10.1002/mnfr.202000178. Online ahead of print.PMID: 32378786
202. Li J#, Guasch-Ferré M, Chung W#, Ruiz-Canela M, Toledo E, Corella D, Bhupathiraju SN, Tobias DK, Tabung FK, Hu J, Zhao T#, Turman C, Feng YA#, Clish CB, Mucci L, Eliassen AH, Costenbader KH, Karlson EW, Wolpin BM, Ascherio A, Rimm EB, Manson JE, Qi L, Martínez-González MÁ, Salas-Salvadó J, Hu FB*, Liang L*. (2020) The Mediterranean diet, plasma metabolome, and cardiovascular disease risk. Eur Heart J. 2020 May 14:ehaa209. doi: 10.1093/eurheartj/ehaa209. Online ahead of print.PMID: 32406924 (The EHJ editorial introducing our study PMID: 32357245, Sanjay Sharma, Gemma Parry-Williams, Sabiha Gati. The metabolic signature: an emerging paradigm in cardiovascular nutritional health research?)
203. Zhu Z#, Hasegawa K, Ma B, Fujiogi M, Camargo CA Jr, Liang L*. (2020) Association of asthma and its genetic predisposition with the risk of severe COVID-19. J Allergy Clin Immunol. 2020 Aug;146(2):327-329.e4. PMID: 32522462 PMCID: PMC7423602
204. Ma J, Rebholz CM, Braun KVE, Reynolds LM, Aslibekyan S, Xia R, Biligowda NG, Huan T, Liu C, Mendelson MM, Joehanes R, Hu EA, Vitolins MZ, Wood AC, Lohman K, Ochoa-Rosales C, van Meurs J, Uitterlinden A, Liu Y, Elhadad MA, Heier M, Waldenberger M, Peters A, Colicino E, Whitsel EA, Baldassari A, Gharib SA, Sotoodehnia N, Brody JA, Sitlani CM, Tanaka T, Hill WD, Corley J, Deary IJ, Zhang Y, Schöttker B, Brenner H, Walker ME, Ye S, Nguyen S, Pankow J, Demerath EW, Zheng Y, Hou L, Liang L, Lichtenstein AH, Hu FB, Fornage M, Voortman T, Levy D. (2020) Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality. Circ Genom Precis Med. 2020 Aug;13(4):e002766.
205. Haslam DE, Li J, Liang L, Martinez M, Palacios C, Trak-Fellermeier MA, Franks PW, Joshipura K, Bhupathiraju SN. (2020) Changes in Metabolites During an Oral Glucose Tolerance Test in Early and Mid-Pregnancy: Findings from the PEARLS Randomized, Controlled Lifestyle Trial. Metabolites. 2020 Jul 10;10(7):284.
206. Zhu Z#, Hasegawa K, Camargo CA Jr, Liang L*. (2020) Investigating asthma heterogeneity through shared and distinct genetics: Insights from genome-wide cross-trait analysis. J Allergy Clin Immunol. 2020 Jul 18:S0091-6749(20)30966-0. PMID: 32693092 PMCID: PMC7368660
207. Hang D, Zeleznik OA, He X, Guasch-Ferre M, Jiang X, Li J, Liang L, Eliassen AH, Clish CB, Chan AT, Hu Z, Shen H, Wilson KM, Mucci LA, Sun Q, Hu FB, Willett WC, Giovannucci EL, Song M. (2020) Metabolomic Signatures of Long-term Coffee Consumption and Risk of Type 2 Diabetes in Women. Diabetes Care. 2020 Oct;43(10):2588-2596.
208. Zhu Z#, Hasegawa K, Ma B, Fujiogi M, Camargo CA Jr, Liang L*. (2020) Association of obesity and its genetic predisposition with the risk of severe COVID-19: Analysis of population-based cohort data. Metabolism. 2020 Aug 22;112:154345. PMID: 32835759 PMCID: PMC7442576
209. Papandreou C, Hernández-Alonso P, Bulló M, Ruiz-Canela M, Li J, Guasch-Ferré M, Toledo E, Clish C, Corella D, Estruch R, Cofán M, Fitó M, Razquin C, Arós F, Fiol M, Santos-Lozano JM, Serra-Majem L, Liang L, Martínez-González MA, Hu FB, Salas-Salvadó J. (2020) High Plasma Glutamate and a Low Glutamine-to-Glutamate Ratio Are Associated with Increased Risk of Heart Failure but Not Atrial Fibrillation in the Prevención con Dieta Mediterránea (PREDIMED) Study. J Nutr. 2020 Nov 19;150(11):2882-2889. PMID: 32939552 PMCID: PMC7675032
210. Hong X, Zhang B, Liang L, Zhang Y, Ji Y, Wang G, Ji H, Clish CB, Burd I, Pearson C, Zuckerman B, Hu FB, Wang X. (2020) Postpartum plasma metabolomic profile among women with preeclampsia and preterm delivery: implications for long-term health. BMC Med. 2020 Oct 13;18(1):277.
211. Mei Z, Dong X, Qian Y, Hong D, Xie Z, Yao G, Qin A, Gao S, Hu J, Liang L*, Zheng Y*, Su J*. (2020) Association between the metabolome and bone mineral density in a Chinese population. EBioMedicine. 2020 Nov 10;62:103111.
212. Papandreou C, Bulló M, Hernández-Alonso P, Ruiz-Canela M, Li J, Guasch-Ferré M, Toledo E, Clish C, Corella D, Estruch R, Ros E, Fitó M, Alonso-Gómez A, Fiol M, Santos-Lozano JM, Serra-Majem L, Liang L, Martínez-González MA, Hu FB, Salas-Salvadó J. (2020) Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study. Clin Chem. 2020 Nov 30:hvaa224. doi: 10.1093/clinchem/hvaa224. PMID: 33257943 PMCID: PMC7793226
213. Wittenbecher C, Eichelmann F, Toledo E, Guasch-Ferre M, Ruiz-Canela M, Li J, Arós Borau F, Lee CH, Liang L, Salas-Salvadó J, Clish CB, Schulze MB, Martínez-González MA, Hu FB. (2020) Lipid Profiles and Heart Failure Risk: Results from Two Prospective Studies. Circ Res.2020 Dec 4. doi: 10.1161/CIRCRESAHA.120.317883. PMID: 33272114 PMCID: PMC7864881
214. Feng YA#, Guo Y, Pain L, Lathrop GM, Laprise C, Moffatt MF, Cookson WOCM, Liang L*(2020) Estimating cell-type specific DNA methylation effects in heterogeneous cellular populations. Epigenomics PMID: 33350870
215. Lin Y#, Yin P, Zhu Z#, Peng Y, Li M, Li J, Liang L*, Yu X* (2020) Epigenome-wide Association Study and Network Analysis for IgA Nephropathy from CD19 + B-cell in Chinese Population. Epigenetics PMID: 33319642
216. Yun H, Sun L, Wu Q, Zong G, Qi Q, Li H, Zheng H, Zeng R*, Liang L*, Lin X*. (2020) Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China. PLoS Med. 2020 Dec 9;17(12):e1003451. doi: 10.1371/journal.pmed.1003451. PMID: 33296380

2021

217. Drouin-Chartier JP, Hernández-Alonso P, Guasch-Ferré M, Ruiz-Canela M, Li J, Wittenbecher C, Razquin C, Toledo E, Dennis C, Corella D, Estruch R, Fitó M, Eliassen AH, Tobias DK, Ascherio A, Mucci LA, Rexrode KM, Karlson EW, Costenbader KH, Fuchs CS,Liang L, Clish CB, Martínez-González MA, Salas-Salvadó J, Hu FB. (2021) Dairy consumption, plasma metabolites, and risk of type 2 diabetes. The American Journal of Clinical Nutrition 2021 Jul 1;114(1):163-174. doi: 10.1093/ajcn/nqab047. PMID: 33742198
218. Si J#, Li J, Yu C, Guo Y, Bian Z, Millwood IY, Yang L, Walters RG, Chen Y, Du H, Yin L, Chen J, Chen J, Chen Z, Li L*, Liang L*, Lv J*; on behalf of the China Kadoorie Biobank Collaborative Group (2021) Improved lipidomic profile mediates the effects of adherence to healthy lifestyles on coronary heart disease. eLife 10:e60999. PMID: 33558007
219. Zhu Z#, Li J, Si J#, Ma B#, Shi H, Lv J, Cao W, Guo Y, Millwood I, Walters R, Lin K, Yang L, Chen Y, Du H, Yu B, Hasegawa K, Camargo CA, Moffatt MF, Cookson WOC, Chen J, Chen Z, Li L, Yu C*, Liang L*. (2021) A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. European Respiratory Journal 58(4):2100199.
220. Guasch-Ferre M, Hernandez-Alonso P, Drouin-Chartier JP, Ruiz-Canela M, Razquin C, Toledo E, Li J, Dennis C, Wittenbecher C, Corella D, Estruch R, Fito M, Ros E, Babio N, Bhupathiraju SN, Clish CB, Liang L, Martinez-Gonzalez MA, Hu FB, Salas-Salvado J. (2021) Walnut Consumption, Plasma Metabolomics, and Risk of Type 2 Diabetes and Cardiovascular Disease. J Nutr. 151(2):303-311. PMC7850062.
221. Bulló M, Papandreou C, Ruiz-Canela M, Guasch-Ferré M, Li J, Hernández-Alonso P, Toledo E, Liang L, Razquin C, Corella D, Estruch R, Ros E, Fitó M, Arós F, Fiol M, Serra-Majem L, Clish CB, Becerra-Tomás N, Martínez-González MA, Hu FB, Salas-Salvadó J. (2021) Plasma Metabolomic Profiles of Glycemic Index, Glycemic Load, and Carbohydrate Quality Index in the PREDIMED Study. J Nutr. 2021 Jan 4;151(1):50-58. doi: 10.1093/jn/nxaa345. PMID: 33296468
222. Long P, Wang Q, Zhang Y, Zhu X, Yu K, Jiang H, Liu X, Zhou M, Yuan Y, Liu K, Jiang J, Zhang X, He M, Guo H, Chen W, Yuan J, Cheng L, Liang L, Wu T. (2021) Profile of copper-associated DNA methylation and its association with incident acute coronary syndrome. Clin Epigenetics. 13(1):19. doi: 10.1186/s13148-021-01004-w. PMID: 33499918
223. Raita Y, Zhu Z#, Freishtat RJ, Fujiogi M, Liang L, Patregnani JT, Camargo CA, Hasegawa K. (2021) Soluble receptor for advanced glycation end products (sRAGE) and asthma: Mendelian randomisation study. Pediatr Allergy Immunol. doi: 10.1111/pai.13478. Online ahead of print. PMID: 33599351
224. Xu R, Hong X, Zhang B, Huang W, Hou W, Wang G, Wang X, Igusa T, Liang L, Ji H. (2021) DNA methylation mediates the effect of maternal smoking on offspring birthweight: a birth cohort study of multi-ethnic US mother-newborn pairs. Clin Epigenetics. 13(1):47. doi: 10.1186/s13148-021-01032-6. PMID: 33663600
225. Yaskolka Meir A#, Keller M, Bernhart SH, Rinott E, Tsaban G, Zelicha H, Kaplan A, Schwarzfuchs D, Shelef I, Gepner Y, Li J#, Lin Y#, Blüher M, Ceglarek U, Stumvoll M, Stadler PF, Stampfer MJ, Kovacs P, Liang L*, Shai I*. (2021) Lifestyle weight-loss intervention may attenuate methylation aging: the CENTRAL MRI randomized controlled trial. Clin Epigenetics. 13(1):48. doi: 10.1186/s13148-021-01038-0. PMID: 33663610
226. Rahman ML*, Feng YA#*, Fiehn O, Albert PS, Tsai MY, Zhu Y, Wang X, Tekola-Ayele F, Liang L*, Zhang C*. (2021) Plasma lipidomics profile in pregnancy and gestational diabetes risk: a prospective study in a multiracial/ethnic cohort. BMJ Open Diabetes Res Care.9(1):e001551. doi: 10.1136/bmjdrc-2020-001551. PMID: 33674279
227. Shen M, Xu X, Liu X, Wang Q, Li W, You X, Peng R, Yuan Y, Long P, Niu R, Yang H, Cheng X, Pan A, Tanguay RM, Zhang X, He M, Wang C, Liang L, Wu T. (2021) Prospective Study on Plasma MicroRNA-4286 and Incident Acute Coronary Syndrome. J Am Heart Assoc.10(6):e018999. doi: 10.1161/JAHA.120.018999.PMID: 33719498
228. Salas LA, Peres LC, Thayer ZM, Smith RW, Guo Y#, Chung W#, Si J#, Liang L*. (2021) A transdisciplinary approach to understand the epigenetic basis of race/ethnicity health disparities. Epigenomics. doi: 10.2217/epi-2020-0080. PMID: 33719520
229. Wang F, Wu K, Li Y, Song R, Wu Y, Zhang X, Song M, Liang L, Smith-Warner SA, Giovannucci EL, Willett WC. (2021) Association of folate intake and colorectal cancer risk in the postfortification era in US women. Am J Clin Nutr. 2021 Jul 1;114(1):49-58. doi: 10.1093/ajcn/nqab035. PMID: 33742202
230. Mendez KM, Kim J, Laíns I, Nigalye A, Katz R, Pundik S, Kim IK, Liang L, Vavvas DG, Miller JB, Miller JW, Lasky-Su JA, Husain D. (2021) Association of Human Plasma Metabolomics with Delayed Dark Adaptation in Age-Related Macular Degeneration. Metabolites. 2021 Mar 21;11(3):183. doi: 10.3390/metabo11030183. PMID: 33801085
231. Raita Y, Camargo CA Jr, Liang L, Hasegawa K. (2021) Leveraging “big data” in respiratory medicine – data science, causal inference, and precision medicine. Expert Rev Respir Med.2021 Jun;15(6):717-721. doi: 10.1080/17476348.2021.1913061. Epub 2021 Apr 15. PMID: 33818245
232. Liu G, Li J#, Li Y, Hu Y, Franke AA, Liang L, Hu FB, Chan AT, Mukamal KJ, Rimm EB, Sun Q. (2021) Gut microbiota-derived metabolites and risk of coronary artery disease: a prospective study among US men and women. Am J Clin Nutr. 2021 Jul 1;114(1):238-247. doi: 10.1093/ajcn/nqab053. PMID: 33829245
233. Raita Y, Zhu Z#, Camargo CA Jr, Freishtat RJ, Ngo D, Liang L, Hasegawa K. (2021) Relationship of Soluble Interleukin-6 Receptors With Asthma: A Mendelian Randomization Study. Front Med (Lausanne). 2021 Apr 12;8:665057. doi: 10.3389/fmed.2021.665057. eCollection 2021. PMID: 33912579
234. Becerra-Tomás N, Ruiz-Canela M, Hernández-Alonso P, Bulló M, Li J#, Guasch-Ferré M, Toledo E, Clish CB, Estruch R, Ros E, Fitó M, Lee CH, Pierce K, Arós F, Serra-Majem L, Liang L, Razquin C, Gómez-Gracia E, Martínez-González MA, Hu FB, Corella D, Salas-Salvadó J. (2021) Glycolysis Metabolites and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Trial. Metabolites. 2021 May 11;11(5):306. doi: 10.3390/metabo11050306. PMID: 34064960
235. Zhu Z#, Camargo CA Jr, Raita Y, Fujiogi M, Liang L, Rhee EP, Woodruff PG, Hasegawa K. (2021) Metabolome subtyping of severe bronchiolitis in infancy and risk of childhood asthma. J Allergy Clin Immunol. 2021 Jun 10:S0091-6749(21)00899-X. doi: 10.1016/j.jaci.2021.05.036. Online ahead of print. PMID: 34119532
236. Willis-Owen SAG, Domingo-Sabugo C, Starren E, Liang L, Freidin MB, Arseneault M, Zhang Y, Lu SK, Popat S, Lim E, Nicholson AG, Riazalhosseini Y, Lathrop M, Cookson WOC, Moffatt MF. (2021) Y disruption, autosomal hypomethylation and poor male lung cancer survival. Sci Rep. 2021 Jun 14;11(1):12453. doi: 10.1038/s41598-021-91907-8. PMID: 34127738
237. Jin X, Shu C, Zeng Y, Liang L, Ji JS. (2021) Interaction of greenness and polygenic risk score of Alzheimer’s disease on risk of cognitive impairment. Sci Total Environ. 2021 Nov 20;796:148767. doi: 10.1016/j.scitotenv.2021.148767. Epub 2021 Jul 8. PMID: 34273838
238. Razquin C, Ruiz-Canela M, Toledo E, Hernández-Alonso P, Clish CB, Guasch-Ferré M, Li J, Wittenbecher C, Dennis C, Alonso-Gómez A, Fitó M, Liang L, Corella D, Gómez-Gracia E, Estruch R, Fiol M, Lapetra J, Serra-Majem L, Ros E, Aros F, Salas-Salvadó J, Hu FB, Martínez-González MA. (2021) Metabolomics of the tryptophan-kynurenine degradation pathway and risk of atrial fibrillation and heart failure: potential modification effect of Mediterranean diet. Am J Clin Nutr. 2021 Jul 22:nqab238. doi: 10.1093/ajcn/nqab238. Online ahead of print. PMID: 34291275
239. Raita Y, Camargo CA Jr, Liang L, Hasegawa K. (2021) Big Data, Data Science, and Causal Inference: A Primer for Clinicians. Front Med (Lausanne). 2021 Jul 6;8:678047. doi: 10.3389/fmed.2021.678047. eCollection 2021. PMID: 34295910
240. Lin Y, Wu J, Zhu Y, Hinkle SN, Rawal S, Liang L, Weir NL, Tsai MY, Zhang C. (2021) A longitudinal study of plasma acylcarnitines throughout pregnancy and associations with risk of gestational diabetes mellitus. Clin Nutr. 2021 Aug;40(8):4863-4870. doi: 10.1016/j.clnu.2021.07.008. Epub 2021 Jul 10. PMID: 34358830
241. Tindula G, Mukherjee SK, Ekramullah SM, Arman DM, Biswas SK, Islam J, Obrycki JF, Christiani DC, Liang L, Warf BC, Mazumdar M. (2021) Parental metal exposures as potential risk factors for spina bifida in Bangladesh. Environ Int. 2021 Dec;157:106800. doi: 10.1016/j.envint.2021.106800. Epub 2021 Aug 3. PMID: 34358915
242. Lains I, Zhu S#, Han X#, Chung W#, Yuan Q#, Kelly RS, Gil JQ, Katz R, Nigalye A, Kim IK, Miller JB, Carreira IM, Silva R, Vavvas DG, Miller JW, Lasky-Su J, Liang L*, Husain D*. (2021) Genomic-Metabolomic Associations Support the Role of LIPC and Glycerophospholipids in Age-Related Macular Degeneration. Ophthalmol Sci. 2021 Mar;1(1):100017. doi: 10.1016/j.xops.2021.100017. PMID: 34382031
243. Haslam DE, Liang L, Wang DD, Kelly RS, Wittenbecher C, Pérez CM, Martínez M, Lee CH, Clish CB, Wong DTW, Parnell LD, Lai CQ, Ordovás JM, Manson JE, Hu FB, Stampfer MJ, Tucker KL, Joshipura KJ, Bhupathiraju SN. (2021) Associations of network-derived metabolite clusters with prevalent type 2 diabetes among adults of Puerto Rican descent. BMJ Open Diabetes Res Care. 2021 Aug;9(1):e002298. PMID: 34413117
244. Si J#, Yang S, Sun D, Yu C, Guo Y, Lin Y, Millwood I, Walters R, Yang L, Chen Y, Du H, Hua Y, Liu J, Chen J, Chen Z, Chen W, Li L*, Liang L*, Lv J*; China Kadoorie Biobank Collaborative Group. (2021) Epigenome-wide analysis of DNA methylation and coronary heart disease: a nested case-control study. eLife. 2021 Sep 13;10:e68671. PMID: 34515027
245. Phipatanakul W, Koutrakis P, Coull BA, Petty CR, Gaffin JM, Sheehan WJ, Lai PS, Bartnikas LM, Kang CM, Wolfson JM, Samnaliev M, Cunningham A, Baxi SN, Permaul P, Hauptman M, Trivedi M, Louisias M, Liang L, Thorne PS, Metwali N, Adamkiewicz G, Israel E, Baccarelli AA, Gold DR; School Inner-City Asthma Intervention study team. (2021) Effect of School Integrated Pest Management or Classroom Air Filter Purifiers on Asthma Symptoms in Students With Active Asthma: A Randomized Clinical Trial. JAMA. 2021 Sep 7;326(9):839-850. PMID: 34547084
246. Nanishi M, Fujiogi M, Stevenson M, Liang L, Qi YS, Raita Y, Hasegawa K, Camargo CA Jr.(2021) Association of growth trajectory profiles with asthma development in infants hospitalized with bronchiolitis. J Allergy Clin Immunol Pract. 2021 Nov 14:S2213-2198(21)01263-0. doi: 10.1016/j.jaip.2021.11.001.
247. Bulló M, Papandreou C, García-Gavilán J, Ruiz-Canela M, Li J, Guasch-Ferré M, Toledo E, Clish C, Corella D, Estruch R, Ros E, Fitó M, Lee CH, Pierce K, Razquin C, Arós F, Serra-Majem L, Liang L, Martínez-González MA, Hu FB, Salas-Salvadó J. (2021) Tricarboxylic acid cycle related-metabolites and risk of atrial fibrillation and heart failure. Metabolism.2021 Dec;125:154915. doi: 10.1016/j.metabol.2021.154915. Epub 2021 Oct 20.
248. Cao T#, Zhao J#, Hong X, Wang G, Hu F, Wang X*, Liang L* (2021) Cord Blood Metabolome and BMI Trajectory from Birth to Adolescence: A Prospective Birth Cohort Study on Early Life Biomarkers of Persistent Obesity. Metabolites. 11(11):739. doi: 10.3390/metabo11110739. PMID: 34822398
249. Ruiz-Canela M, Guasch-Ferré M, Razquin C, Toledo E, Hernández-Alonso P, Clish CB, Li J, Wittenbecher C, Dennis C, Alonso-Gómez Á, Almanza-Aguilera E, Liang L, Corella D, Gómez-Gracia E, Estruch R, Fiol M, Lapetra J, Serra-Majem L, Ros E, Arós F, Salas-Salvadó J, Hu FB, Martínez-González MÁ. (2021) Plasma acylcarnitines and risk of incident heart failure and atrial fibrillation: the Prevención con dieta mediterránea study. Rev Esp Cardiol (Engl Ed). 2021 Dec 2:S1885-5857(21)00313-3. doi: 10.1016/j.rec.2021.10.005. PMID: 34866031

2022

250. Hong X, Liang L, Ji H, Frischmeyer-Guerrerio P, Wang G, Pearson C, Stampfer M, Hu FB, Wang X. (2022) Fetal lipidome and incident risk of food allergy: A prospective birth cohort study. Pediatr Allergy Immunol. 2022 Feb;33(2):e13722. doi: 10.1111/pai.13722. PMID: 34918394
251. Wittenbecher C, Guasch-Ferré M, Haslam DE, Dennis C, Li J, Bhupathiraju SN, Lee CH, Qi Q, Liang L, Eliassen AH, Clish C, Sun Q, Hu FB. (2022) Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses’ Health Study. EBioMedicine. 2022 Jan;75:103799. doi: 10.1016/j.ebiom.2021.103799. Epub 2021 Dec 31. PMID: 34979341
252. Zhang M, Buckley JP, Liang L, Hong X, Wang G, Wang MC, Wills-Karp M, Wang X, Mueller NT. (2022) A metabolome-wide association study of in utero metal and trace element exposures with cord blood metabolome profile: Findings from the Boston Birth Cohort. Environ Int. 2022 Jan;158:106976. doi: 10.1016/j.envint.2021.106976. Epub 2021 Nov 19. PMID: 34991243
253. Hang D, Zeleznik OA, Lu J, Joshi AD, Wu K, Hu Z, Shen H, Clish CB, Liang L, Eliassen AH, Ogino S, Meyerhardt JA, Chan AT, Song M. (2022) Plasma metabolomic profiles for colorectal cancer precursors in women. Eur J Epidemiol. 2022 Jan 15. doi: 10.1007/s10654-021-00834-5. Online ahead of print. PMID: 35032257
254. Lains I, Mendez K, Nigalye A, Katz R, Douglas VP, Kelly RS, Kim IK, Miller JB, Vavvas DG, Liang L, Lasky-Su J, Miller JW, Husain D. (2022) Plasma Metabolomic Profiles Associated with Three-Year Progression of Age-Related Macular Degeneration. Metabolites. 2022 Jan 1;12(1):32. doi: 10.3390/metabo12010032. PMID: 35050154

255. Lains I, Mendez KM, Gil JQ, Miller JB, Kelly RS, Barreto P, Kim IK, Vavvas DG, Murta JN, Liang L, Silva R, Miller JW, Lasky-Su J, Husain D. (2022) Urinary Mass Spectrometry Profiles in Age-Related Macular Degeneration. J Clin Med. 2022 Feb 11;11(4):940. doi: 10.3390/jcm11040940. PMID: 35207212
256. Wang F, Chandler PD, Zeleznik OA, Wu K, Wu Y, Yin K, Song R, Avila-Pacheco J, Clish CB, Meyerhardt JA, Zhang X, Song M, Ogino S, Lee IM, Eliassen AH, Liang L, Smith-Warner SA, Willett WC, Giovannucci EL. (2022) Plasma Metabolite Profiles of Red Meat, Poultry, and Fish Consumption, and Their Associations with Colorectal Cancer Risk. Nutrients. 2022 Feb 25;14(5):978. doi: 10.3390/nu14050978. PMID: 35267954
257. Garrison-Desany HM, Hong X, Maher BS, Beaty TH, Wang G, Pearson C, Liang L, Wang X, Ladd-Acosta C. (2022) Individual and Combined Association Between Prenatal Polysubstance Exposure and Childhood Risk of Attention-Deficit/Hyperactivity Disorder. JAMA Netw Open. 2022 Mar 1;5(3):e221957. doi: 10.1001/jamanetworkopen.2022.1957. PMID: 35275164
258. Wang F, Baden MY, Guasch-Ferré M, Wittenbecher C, Li J#, Li Y, Wan Y, Bhupathiraju SN, Tobias DK, Clish CB, Mucci LA, Eliassen AH, Costenbader KH, Karlson EW, Ascherio A, Rimm EB, Manson JE, Liang L, Hu FB. (2022) Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes. Diabetologia. 2022 Jul;65(7):1119-1132. doi: 10.1007/s00125-022-05692-8. Epub 2022 Apr 8. PMID: 35391539
259. Merino J, Guasch-Ferré M, Li J#, Chung W#, Hu Y, Ma B#, Li Y, Kang JH, Kraft P, Liang L, Sun Q, Franks PW, Manson JE, Willet WC, Florez JC, Hu FB. (2022) Polygenic scores, diet quality, and type 2 diabetes risk: An observational study among 35,759 adults from 3 US cohorts. PLoS Med. 2022 Apr 26;19(4):e1003972. doi: 10.1371/journal.pmed.1003972. eCollection 2022 Apr. PMID: 35472203
260. Goni L, Razquin C, Toledo E, Guasch-Ferré M, Clish CB, Babio N, Wittenbecher C, Atzeni A, Li J#, Liang L, Dennis C, Alonso-Gómez Á, Fitó M, Corella D, Gómez-Gracia E, Estruch R, Fiol M, Lapetra J, Serra-Majem L, Ros E, Arós F, Salas-Salvadó J, Hu FB, Martínez-González MA, Ruiz-Canela M. (2022) Arginine catabolism metabolites and atrial fibrillation or heart failure risk: 2 case-control studies within the Prevención con Dieta Mediterránea (PREDIMED) trial. Am J Clin Nutr. 2022 Sep 2;116(3):653-662. doi: 10.1093/ajcn/nqac139. PMID: 35575609
261. Luo Y, Wang J, Sun L, Gu W, Zong G, Song B, Shen C, Zhou P, Chen Y, Wu Y, Lin H, Zheng H, Ni M, Yang X, Chen Y, Xu X, Zhang J, Shi J, Zhang R, Hu J, Hou H, Lu L, Xu X, Liang L, Liu R, Liu X, Li H, Hong J, Wang W, Lin X, Ning G. (2022) Isocaloric-restricted Mediterranean Diet and Chinese Diets High or Low in Plants in Adults With Prediabetes. J Clin Endocrinol Metab.2022 Jul 14;107(8):2216-2227. doi: 10.1210/clinem/dgac303. PMID: 35579171
262. Haslam DE, Li J#, Dillon ST, Gu X, Cao Y, Zeleznik OA, Sasamoto N, Zhang X, Eliassen AH, Liang L, Stampfer MJ, Mora S, Chen ZZ, Terry KL, Gerszten RE, Hu FB, Chan AT, Libermann TA, Bhupathiraju SN. (2022) Stability and reproducibility of proteomic profiles in epidemiological studies: comparing the Olink and SOMAscan platforms. Proteomics. 2022 Jul;22(13-14):e2100170. doi: 10.1002/pmic.202100170. Epub 2022 May 31. PMID: 35598103
263. Rivas-Tumanyan S, Pacheco LS, Haslam DE, Liang L, Tucker KL, Joshipura KJ, Bhupathiraju SN. (2022) Novel Plasma Metabolomic Markers Associated with Diabetes Progression in Older Puerto Ricans. Metabolites. 2022 Jun 2;12(6):513. doi: 10.3390/metabo12060513. PMID: 35736445
264. Yaskolka Meir A#, Liang L*. (2022) The gut microbiota’s role in diet-related cardiovascular health – an innocent bystander or a key mediator; the question remains. Eur J Prev Cardiol. 2022 Aug 5:167. doi: 10.1093/eurjpc/zwac167. Online ahead of print. PMID: 35929653
265. Wang F, Ugai T, Haruki K, Wan Y, Akimoto N, Arima K, Zhong R, Twombly TS, Wu K, Yin K, Chan AT, Giannakis M, Nowak JA, Meyerhardt JA, Liang L, Song M, Smith-Warner SA, Zhang X, Giovannucci EL, Willett WC, Ogino S. (2022) Healthy and unhealthy plant-based diets in relation to the incidence of colorectal cancer overall and by molecular subtypes. Clin Transl Med. 2022 Aug;12(8):e893. doi: 10.1002/ctm2.893. PMID: 35998061
266. Zhang M, Brady TM, Buckley JP, Appel LJ, Hong X, Wang G, Liang L, Wang X, Mueller NT. (2022) Metabolome-Wide Association Study of Cord Blood Metabolites With Blood Pressure in Childhood and Adolescence. Hypertension. 2022 Sep 16:101161HYPERTENSIONAHA12220139. doi: 10.1161/HYPERTENSIONAHA.122.20139. Online ahead of print. PMID: 36111548
267. Lin Y#, Ma B#, Yang Y#, Chen Y#, Huang J, Li W, Yu X, Liang L*. (2022) Impaired kidney function biomarkers and risk of severe COVID-19: Analysis of population-based cohort data. Mol Genet Genomic Med. 2022 Sep 20:e2047. doi: 10.1002/mgg3.2047. Online ahead of print. PMID: 36124564
268. Han X#, Liang L*. (2022) metabolomicsR: a streamlined workflow to analyze metabolomic data in R. Bioinform Adv. 2022 Sep 16;2(1):vbac067. doi: 10.1093/bioadv/vbac067. eCollection 2022. PMID: 36177485
269. Han X#, Zhu Z#, Xiao Q#, Li J#, Hong X, Wang X, Hasegawa K,Camargo CA, Liang L*. (2022) Unique genetic architecture shared between childhood body mass index and childhood asthma linking to underlying obesity-related biomarkers. Communications Biology 2022 Oct 17;5(1):1098. PMID: 36253437
270. García-Gavilán J, Nishi SK, Paz-Graniel I, Guasch-Ferré M, Razquin C, Clish CB, Toledo E, Ruiz-Canela M, Corella D, Deik A, Drouin-Chartier JP, Wittenbecher C, Babio N, Estruch R, Ros E, Fitó M, Arós F, Fiol M, Serra-Majem L, Liang L, Martínez-González MA, Hu FB, Salas-Salvadó J. (2022) Plasma Metabolite Profiles Associated with the Amount and Source of Meat and Fish Consumption and the Risk of Type 2 Diabetes. Mol Nutr Food Res. 2022 Oct 10:e2200145. doi: 10.1002/mnfr.202200145. Online ahead of print. PMID: 36214069
271. Razquin C, Ruiz-Canela M, Toledo E, Clish CB, Guasch-Ferré M, García-Gavilán JF, Wittenbecher C, Alonso-Gómez A, Fitó M, Liang L, Corella D, Gómez-Gracia E, Estruch R, Fiol M, Santos-Lozano JM, Serra-Majem L, Ros E, Aros F, Salas-Salvadó J, Hu FB, Martínez-González MA. (2022) Circulating Amino Acids and Risk of Peripheral Artery Disease in the PREDIMED Trial. Int J Mol Sci. 2022 Dec 23;24(1):270. PMID: 36613713

2023

272. Santos JL, Ruiz-Canela M, Razquin C, Clish CB, Guasch-Ferré M, Babio N, Corella D, Gómez-Gracia E, Fiol M, Estruch R, Lapetra J, Fitó M, Aros F, Serra-Majem L, Liang L, Martínez MÁ, Toledo E, Salas-Salvadó J, Hu FB, Martínez-González MA. (2023) Circulating citric acid cycle metabolites and risk of cardiovascular disease in the PREDIMED study. Nutr Metab Cardiovasc Dis. 2023 Jan 12:S0939-4753(23)00007-8. PMID: 36739229

273. Semnani-Azad Z, Toledo E, Babio N, Ruiz-Canela M, Wittenbecher C, Razquin C, Wang F, Dennis C, Deik A, Clish CB, Corella D, Fitó M, Estruch R, Arós F, Ros E, García-Gavilan J, Liang L, Salas-Salvadó J, Martínez-González MA, Hu FB, Guasch-Ferré M. (2023) Plasma metabolite predictors of metabolic syndrome incidence and reversion. Metabolism. 2023 Nov 24;151:155742. doi: 10.1016/j.metabol.2023.155742. Online ahead of print. PMID: 38007148

274. Guo Y#, Chung W, Shan Z, Zhu Z, Costenbader KH, Liang L*. (2023) Genome-Wide Assessment of Shared Genetic Architecture Between Rheumatoid Arthritis and Cardiovascular Diseases. J Am Heart Assoc. 2023 Nov 10;12(22):e030211. doi: 10.1161/JAHA.123.030211. Online ahead of print. PMID: 37947095

275. Yaskolka Meir A#, Yun H, Stampfer MJ, Liang L, Hu FB. (2023) Nutrition, DNA methylation and obesity across life stages and generations. Epigenomics. 2023 Oct;15(19):991-1015. doi: 10.2217/epi-2023-0172. Epub 2023 Nov 7. PMID: 37933548

276. Lains I, Han X, Gil J, Providencia J, Nigalye A, Alvarez R, Douglas VP, Mendez K, Katz R, Tsougranis G, Li J, Kelly RS, Kim IK, Lasky-Su J, Silva R, Miller JW, Liang L, Vavvas D, Miller JB, Husain D. (2023) Plasma Metabolites Associated with OCT Features of Age-Related Macular Degeneration. Ophthalmol Sci. 2023 Jul 1;4(1):100357. doi: 10.1016/j.xops.2023.100357. eCollection 2024 Jan-Feb. PMID: 37869026

277. Lee DH, Jin Q, Shi N, Wang F, Bever AM, Liang L, Hu FB, Song M, Zeleznik OA, Zhang X, Joshi A, Wu K, Jeon JY, Meyerhardt JA, Chan AT, Eliassen AH, Clish C, Clinton SK, Giovannucci EL, Li J, Tabung FK. (2023) The metabolic potential of inflammatory and insulinaemic dietary patterns and risk of type 2 diabetes. Diabetologia. 2024 Jan;67(1):88-101. doi: 10.1007/s00125-023-06021-3. Epub 2023 Oct 11. PMID: 37816982

278. Hou W, Zhang M, Ji Y, Hong X, Wang G, Xu R, Liang L, Saria S, Ji H. (2023) A prospective birth cohort study of maternal prenatal cigarette smoking assessed by self-report and biomarkers on childhood risk of overweight or obesity. Precis Nutr. 2022 Dec 7;1(3):e00017. doi: 10.1097/PN9.0000000000000017. eCollection 2022 Dec. PMID: 37744083

279. Li X, Hur J, Cao Y, Song M, Smith-Warner SA, Liang L, Mukamal KJ, Rimm EB, Giovannucci EL. (2023) Moderate alcohol consumption, types of beverages and drinking pattern with cardiometabolic biomarkers in three cohorts of US men and women. Eur J Epidemiol. 2023 Nov;38(11):1185-1196. doi: 10.1007/s10654-023-01053-w. Epub 2023 Sep 25. PMID: 37747628

280. Huang W, Meir AY#, Olapeju B, Wang G, Hong X, Venkataramani M, Cheng TL, Igusa T,Liang L*, Wang X*. (2023) Defining longitudinal trajectory of body mass index percentile and predicting childhood obesity: methodologies and findings in the Boston Birth Cohort. Precis Nutr. 2023 Apr 21;2(2):e00037. doi: 10.1097/PN9.0000000000000037. eCollection 2023 Jun. PMID: 37745028

281. Yaskolka Meir A#, Keller M, Hoffmann A, Rinott E, Tsaban G, Kaplan A, Zelicha H, Hagemann T, Ceglarek U, Isermann B, Shelef I, Blüher M, Stumvoll M, Li J, Haange SB, Engelmann B, Rolle-Kampczyk U, von Bergen M, Hu FB, Stampfer MJ, Kovacs P, Liang L*, Shai I*. (2023) The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial. BMC Med. 2023 Sep 25;21(1):364. doi: 10.1186/s12916-023-03067-3. PMID: 37743489

282. Wang F, Tessier AJ, Liang L, Wittenbecher C, Haslam DE, Fernández-Duval G, Heather Eliassen A, Rexrode KM, Tobias DK, Li J, Zeleznik O, Grodstein F, Martínez-González MA, Salas-Salvadó J, Clish C, Lee KH, Sun Q, Stampfer MJ, Hu FB, Guasch-Ferré M. (2023) Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals. Nat Commun. 2023 Sep 16;14(1):5744. doi: 10.1038/s41467-023-41515-z. PMID: 37717037

283. Rios S, García-Gavilán JF, Babio N, Paz-Graniel I, Ruiz-Canela M, Liang L, Clish CB, Toledo E, Corella D, Estruch R, Ros E, Fitó M, Arós F, Fiol M, Guasch-Ferré M, Santos-Lozano JM, Li J, Razquin C, Martínez-González MÁ, Hu FB, Salas-Salvadó J. (2023) Plasma metabolite profiles associated with the World Cancer Research Fund/American Institute for Cancer Research lifestyle score and future risk of cardiovascular disease and type 2 diabetes. Cardiovasc Diabetol. 2023 Sep 16;22(1):252. doi: 10.1186/s12933-023-01912-6. PMID: 37716984

284. Zhu Z, Li Y, Freishtat RJ, Celedón JC, Espinola JA, Harmon B, Hahn A, Camargo CA Jr, Liang L*, Hasegawa K*. (2023) Epigenome-wide association analysis of infant bronchiolitis severity: a multicenter prospective cohort study. Nat Commun. 2023 Sep 7;14(1):5495. doi: 10.1038/s41467-023-41300-y. PMID: 37679381

285. Si J#, Meir AY#, Hong X, Wang G, Huang W, Pearson C, Adams WG, Wang X, Liang L.* (2023) Maternal pre-pregnancy BMI, offspring epigenome-wide DNA methylation, and childhood obesity: findings from the Boston Birth Cohort. BMC Med. 2023 Aug 23;21(1):317. doi: 10.1186/s12916-023-03003-5. PMID: 37612641

286. Li Y, Hong X, Liang L, Wang X, Ladd-Acosta C. (2023) Association between acetaminophen metabolites and CYP2E1 DNA methylation level in neonate cord blood in the Boston Birth Cohort. Clin Epigenetics. 2023 Aug 18;15(1):132. doi: 10.1186/s13148-023-01551-4. PMID: 37596607

287. Liu J, Roberts AL, Lawn RB, Jha SC, Sampson L, Sumner JA, Kang JH, Rimm EB, Grodstein F, Liang L, Haneuse S, Kubzansky LD, Koenen KC, Chibnik LB. (2023) Post-traumatic stress disorder symptom remission and cognition in a large cohort of civilian women. Psychol Med. 2023 Aug 14:1-12. doi: 10.1017/S0033291723001915. Online ahead of print. PMID: 37577959

288. Lee DH, Jin Q, Shi N, Wang F, Bever AM, Li J, Liang L, Hu FB, Song M, Zeleznik OA, Zhang X, Joshi A, Wu K, Jeon JY, Meyerhardt JA, Chan AT, Eliassen AH, Clish CB, Clinton SK, Giovannucci EL, Tabung FK. (2023) Dietary Inflammatory and Insulinemic Potentials, Plasma Metabolome and Risk of Colorectal Cancer. Metabolites. 2023 Jun 12;13(6):744. doi: 10.3390/metabo13060744. PMID: 37367904

289. Han X#, Lains I, Li J#, Li J#, Chen Y, Yu B, Qi Q, Boerwinkle E, Kaplan R, Thyagarajan B, Daviglus M, Joslin CE, Cai J, Guasch-Ferré M, Tobias DK, Rimm E, Ascherio A, Costenbader K, Karlson E, Mucci L, Eliassen AH, Zeleznik O, Miller J, Vavvas DG, Kim IK, Silva R, Miller J, Hu F, Willett W, Lasky-Su J, Kraft P, Richards JB, MacGregor S, Husain D, Liang L.* (2023) Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration. Cell Rep Med. 2023 Jul 18;4(7):101085. doi: 10.1016/j.xcrm.2023.101085. Epub 2023 Jun 21. PMID: 37348500

290. Hoffmann A, Meir AY, Hagemann T, Czechowski P, Müller L, Engelmann B, Haange SB, Rolle-Kampczyk U, Tsaban G, Zelicha H, Rinott E, Kaplan A, Shelef I, Stumvoll M, Blüher M, Liang L, Ceglarek U, Isermann B, von Bergen M, Kovacs P, Keller M, Shai I. (2023) A polyphenol-rich green Mediterranean diet enhances epigenetic regulatory potential: the DIRECT PLUS randomized controlled trial. Metabolism. 2023 Aug;145:155594. doi: 10.1016/j.metabol.2023.155594. Epub 2023 May 24. PMID: 37236302

291. Xu R, Hong X, Ladd-Acosta C, Buckley JP, Choi G, Wang G, Hou W, Wang X, Liang L, Ji H. J (2023) Contrasting Association of Maternal Plasma Biomarkers of Smoking and 1-Carbon Micronutrients with Offspring DNA Methylation: Evidence of Aryl Hydrocarbon Receptor Repressor Gene-Smoking-Folate Interaction. Nutr. 2023 Aug;153(8):2339-2351. doi: 10.1016/j.tjnut.2023.05.002. Epub 2023 May 6. PMID: 37156443

292. Meir AY#, Huang W, Cao T, Hong X, Wang G, Pearson C, Adams WG, Wang X, Liang L*. (2023) Umbilical cord DNA methylation is associated with body mass index trajectories from birth to adolescence. EBioMedicine. 2023 May;91:104550. doi: 10.1016/j.ebiom.2023.104550. Epub 2023 Apr 21. PMID: 37088033

293. Wang G, Xu R, Zhang B, Hong X, Bartell TR, Pearson C, Liang L, Wang X. (2023) Impact of intrauterine exposure to maternal diabetes on preterm birth: fetal DNA methylation alteration is an important mediator. Clin Epigenetics. 2023 Apr 7;15(1):59. doi: 10.1186/s13148-023-01473-1. PMID: 37029435

294. Toledo E, Wittenbecher C, Razquin C, Ruiz-Canela M, Clish CB, Liang L, Alonso A, Hernández-Alonso P, Becerra-Tomás N, Arós-Borau F, Corella D, Ros E, Estruch R, García-Rodríguez A, Fitó M, Lapetra J, Fiol M, Alonso-Gomez ÁM, Serra-Majem L, Deik A, Salas-Salvadó J, Hu FB, Martínez-González MA. (2023) Plasma lipidome and risk of atrial fibrillation: results from the PREDIMED trial. J Physiol Biochem. 2023 May;79(2):355-364. doi: 10.1007/s13105-023-00958-0. Epub 2023 Apr 1. PMID: 37004634

295. Si J, Chen L, Yu C, Guo Y, Sun D, Pang Y, Millwood IY, Walters RG, Yang L, Chen Y, Du H, Feng S, Yang X, Avery D, Chen J, Chen Z, Liang L, Li L, Lv J; China Kadoorie Biobank Collaborative Group. (2023) Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease. Clin Epigenetics. 2023 Mar 28;15(1):52. doi: 10.1186/s13148-023-01464-2. PMID: 36978155

296. Hu J#, Xu X, Li J, Jiang Y, Hong X, Rexrode KM, Wang G, Hu FB, Zhang H, Karmaus WJ, Wang X, Liang L.* (2023) Sex differences in the intergenerational link between maternal and neonatal whole blood DNA methylation: a genome-wide analysis in 2 birth cohorts. Clin Epigenetics. 2023 Mar 25;15(1):51. doi: 10.1186/s13148-023-01442-8. PMID: 36966332

297. Ooka T, Zhu Z, Liang L, Celedon JC, Harmon B, Hahn A, Rhee EP, Freishtat RJ, Camargo CA Jr, Hasegawa K. (2023) Integrative genetics-metabolomics analysis of infant bronchiolitis-childhood asthma link: A multicenter prospective study. Front Immunol. 2023 Feb 2;13:1111723. doi: 10.3389/fimmu.2022.1111723. eCollection 2022. PMID: 36818476

298. Cao T#, Zhao J#, Hong X, Wang G, Pearson C, Adams WG, Hu FB, Wang X, Liang L.* (2023) Cord Blood Plasma Metabolome-wide Associations With Height From Birth to Adolescence. J Bone Miner Res. 2023 May;38(5):707-718. doi: 10.1002/jbmr.4790. Epub 2023 Mar 8. PMID: 36805685

299. Hu Y, Liu G, Yu E, Wang B, Wittenbecher C, Manson JE, Rimm EB, Liang L, Rexrode K, Willett WC, Hu FB, Sun Q. (2023) Low-Carbohydrate Diet Scores and Mortality Among Adults With Incident Type 2 Diabetes. Diabetes Care. 2023 Apr 1;46(4):874-884. doi: 10.2337/dc22-2310. PMID: 36787923

Other publications

Development and/or publication of educational materials

Liang, L. (2012) Using genomics-based approaches to uncover genes linked to asthma. Frontiers in Research Articles Series, Nature Education/Bedford Freeman Worth (invited article, in press)