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Globorisk

Globorisk is the first cardiovascular disease risk score that predicts risk of heart attack or stroke in healthy individuals (those who have not yet had a heart attack or stroke) for all countries in the world. It uses information on a person’s country of residence, age, sex, smoking, diabetes, blood pressure and cholesterol to predict the chance that they would have a heart attack or stroke in the next 10 years. If the person does not have a recent diabetes or cholesterol test, they can use the office-based version of Globorisk which is based on body weight and height instead.

Lab Risk Charts

Office Risk Charts

    Patients with the same risk factor profile have higher risk of heart disease or stroke in low- and middle-income countries than high-income countries.

    Proportion of adults at high-risk of heart disease or stroke ranges from 1% for South Korean women to 42% Czech men in high-income countries.

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    Screening and diagnosis of diabetes substantially increases the validity of predicted risk of heart disease or stroke.

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Who we are

Globorisk has been developed a team of collaborators from Harvard TH Chan School of Public Health, Imperial College London and The George Institute for Global Health at Oxford University. Collaborators from many other universities and public health organizations have contributed to the design and implementation of the model. The full list of collaborators is available in the corresponding publications.

Publications

Derivation, internal validation, and recalibration of a cardiovascular risk score for Latin America and the Caribbean (Globorisk-LAC): A pooled analysis of cohort studies.
Cohorts Consortium of Latin America and the Caribbean (CC-LAC). Lancet Reg Health Am. 2022 May;9:None. doi: 10.1016/j.lana.2022.100258. PMID: 35711683 Free PMC article.

Laboratory-based and office-based risk scores and charts to predict 10-year risk of cardiovascular disease in 182 countries: a pooled analysis of prospective cohorts and health surveys.
Ueda P, Woodward M, Lu Y, Hajifathalian K, Al-Wotayan R, Aguilar-Salinas CA, Ahmadvand A, Azizi F, Bentham J, Cifkova R, Di Cesare M, Eriksen L, Farzadfar F, Ferguson TS, Ikeda N, Khalili D, Khang YH, Lanska V, León-Muñoz L, Magliano DJ, Margozzini P, Msyamboza KP, Mutungi G, Oh K, Oum S, Rodríguez-Artalejo F, Rojas-Martinez R, Valdivia G, Wilks R, Shaw JE, Stevens GA, Tolstrup JS, Zhou B, Salomon JA, Ezzati M, Danaei G. Lancet Diabetes Endocrinol. 2017 Mar;5(3):196-213. doi: 10.1016/S2213-8587(17)30015-3. Epub 2017 Jan 24. PMID: 28126460 Free PMC article.

A novel risk score to predict cardiovascular disease risk in national populations (Globorisk): a pooled analysis of prospective cohorts and health examination surveys.
Hajifathalian K, Ueda P, Lu Y, Woodward M, Ahmadvand A, Aguilar-Salinas CA, Azizi F, Cifkova R, Di Cesare M, Eriksen L, Farzadfar F, Ikeda N, Khalili D, Khang YH, Lanska V, León-Muñoz L, Magliano D, Msyamboza KP, Oh K, Rodríguez-Artalejo F, Rojas-Martinez R, Shaw JE, Stevens GA, Tolstrup J, Zhou B, Salomon JA, Ezzati M, Danaei G. Lancet Diabetes Endocrinol. 2015 May;3(5):339-55. doi: 10.1016/S2213-8587(15)00081-9. Epub 2015 Mar 26. PMID: 25819778

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