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Apple Women’s Health Study

The Apple Women’s Health Study is the first long-term research study of this scale and scope that aims to advance the understanding of menstrual cycles and their relationship to various health conditions.

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Publications

Trends in sensor-based health metrics during and after pregnancy: descriptive data from the apple women’s health study

American Journal of Obstetrics & Gynecology Global Reports, August 2024: This study aims to describe changes in physiologic and behavioral sensor-based health metrics during pregnancy and postpartum in the Apple Women’s Health Study and their relationship to demographic factors.

Irregular cycles, ovulatory disorders, and cardiometabolic conditions in a US-based digital cohort

The Journal of the American Medical Association Network Open, May 2024: This study examines the association of PCOS, time to regularity since menarche, and irregular cycles with cardiometabolic conditions in the Apple Women’s Health Study.

Menstrual cycle length variation by demographic characteristics from the Apple Women’s Health Study

Nature Digital Medicine, May 2023: Menstrual characteristics are important signs of overall health. Here we examine the variation of menstrual cycle length by age, ethnicity, and body weight using cycles from over 12,000 participants in the Apple Women’s Health Study.

Abnormal uterine bleeding patterns determined through menstrual tracking among participants in the Apple Women’s Health Study

American Journal of Obstetrics and Gynecology, October 2022: This study aimed to identify abnormal uterine bleeding patterns and their prevalence and confirm existing and expected associations between abnormal uterine bleeding patterns, demographics, and medical conditions.

Irregular cycles, ovulatory disorders, and cardiometabolic conditions in a US-based digital cohort

The Journal of the American Medical Association Network Open, May 2024: This study examines the association of PCOS, time to regularity since menarche, and irregular cycles with cardiometabolic conditions in the Apple Women’s Health Study.

Menstrual cycle length variation by demographic characteristics from the Apple Women’s Health Study

Nature Digital Medicine, May 2023: Menstrual characteristics are important signs of overall health. Here we examine the variation of menstrual cycle length by age, ethnicity, and body weight using cycles from over 12,000 participants in the Apple Women’s Health Study.

Menarche and time to cycle regularity among individuals born between 1950 and 2005 in the US

The Journal of the American Medical Association Network Open, May 2024: This study examines the temporal trends in age at menarche and cycle regularity of individuals born between 1950 to 2005 in the Apple Women’s Health Study.

Seasonal variations of menstrual cycle length in a large, US-based, digital cohort

International Journal of Hygiene and Environmental Health, December 2023: This study examines and quantifies seasonal patterns in menstrual cycle length of over 17,000 participants in the Apple Women’s Health Study.

Covid-19 vaccination and menstrual cycle length in the Apple Women’s Health Study

Nature Digital Medicine, November 2022: COVID-19 vaccination may be associated with change in menstrual cycle length following vaccination. We estimated covariate-adjusted differences in mean cycle length (MCL), measured in days, between pre-vaccination cycles, vaccination cycles, and post-vaccination cycles within vaccinated participants who met eligibility criteria in the Apple Women’s Health Study, a longitudinal mobile-application-based cohort of people in the U.S. with manually logged menstrual cycles.

Menarche and time to cycle regularity among individuals born between 1950 and 2005 in the US

The Journal of the American Medical Association Network Open, May 2024: This study examines the temporal trends in age at menarche and cycle regularity of individuals born between 1950 to 2005 in the Apple Women’s Health Study.

Seasonal variations of menstrual cycle length in a large, US-based, digital cohort

International Journal of Hygiene and Environmental Health, December 2023: This study examines and quantifies seasonal patterns in menstrual cycle length of over 17,000 participants in the Apple Women’s Health Study.

Covid-19 vaccination and menstrual cycle length in the Apple Women’s Health Study

Nature Digital Medicine, November 2022: COVID-19 vaccination may be associated with change in menstrual cycle length following vaccination. We estimated covariate-adjusted differences in mean cycle length (MCL), measured in days, between pre-vaccination cycles, vaccination cycles, and post-vaccination cycles within vaccinated participants who met eligibility criteria in the Apple Women’s Health Study, a longitudinal mobile-application-based cohort of people in the U.S. with manually logged menstrual cycles.