Research Scientists

Yann Cormerais

Research Scientist

Molecular Metabolism, Harvard T.H. Chan School of Public Health

Departments

Department of Molecular Metabolism

Biography

Growth factor-independent mTORC1 signaling promotes primary cilia length via suppression of autophagy.

Shin J, Tighanimine K, Cormerais Y, Rosenthal DM, Niroula P, Lapp SC, Kalafut KC, Cisse MY, Schrötter S, Manning BD. iScience 2025 Dec 19

PMID: 41476940
Dietary protein governs the role of insulin signaling in the postprandial regulation of hepatic mTORC1.

Kalafut KC, Cormerais Y, Cissé MY, Lapp SC, Inouye KE, Hotamisligil GS, Manning BD. bioRxiv 2025 Oct 03

PMID: 41256362
AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth.

Cormerais Y, Lapp SC, Kalafut KC, Cissé MY, Shin J, Stefadu B, Personnaz J, Schrötter S, Freed J, D'Amore A, Martin ER, Salussolia CL, Sahin M, Menon S, Byles V, Manning BD. Dev Cell 2025 Oct 06

PMID: 40480230
De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma.

Teisseire M, Sahu U, Parola J, Tsai MC, Vial V, Durivault J, Grépin R, Cormerais Y, Molina C, Gouraud A, Pagès G, Ben-Sahra I, Giuliano S. Cancer Res 2025 May 15

PMID: 40029310
Growth Factor-Independent mTORC1 Signaling Promotes Primary Cilia Length via Suppression of Autophagy.

Shin J, Cormerais Y, Tighanimine K, Niroula P, Cisse MY, Lapp SC, Kalafut KC, Schrötter S, Manning BD. bioRxiv 2025 May 07

PMID: 40654821

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