Vincent Jaddoe

Biography

Dr. Jaddoe (1974) is Pediatrician and Professor of Pediatric Epidemiology. He is Principal Investigator of the Generation R Study, a population-based prospective cohort study among 10,000 pregnant women and their children in Rotterdam, The Netherlands. His research is focused on 3 main themes: (1) Maternal and fetal health;(2) Fetal and infant programming of common childhood diseases; (3) Genetics and epigenetics of common childhood diseases. General aim of this research is to explore how genetic variants and environmental exposures lead to maternal gestational complications, fetal and childhood developmental adaptation mechanisms, and risk factors for common diseases. Specific interest is in the identification of early critical periods and mechanisms leading to risk factors for diseases in later life. Main diseases of interest include cardiovascular disease, type 2 diabetes, obesity and respiratory diseases. Genetic association studies are embedded in the Early Growth Genetics (EGG) Consortium and Early Growth & Longitudinal Epidemiology (EAGLE) Consortium, in which various birth cohorts (>30,000 subjects) combine their genome wide association studies efforts.

Publications

• Maternal lifestyle risk factors and human embryonic morphologic development using 3D ultrasound: a population-based prospective cohort study.

  Graafland N, Posthumus AG, Mulders AGMGJ, Gaillard R, Koning AHJ, Jaddoe VWV, Steegers EAP, Rousian M. Hum Reprod 2026 Oct 01

  PMID: 42600051

• Genome-wide analysis of social behaviour across social domains, reporters and developmental stages: a meta-regression approach.

  de Hoyos L, Schlag F, Jahagirdar S, Corfield EC, Allegrini AG, Admiraal D, de Zeeuw EL, Nolte IM, Llonga N, Neumann A, Lange K, van den Bedem S, Du Rietz E, Motazedi E, Eising E, Ng NYT, Palviainen T, Wang CA, Thiering E, Scatolin S, Choudhary P, Vilor-Tejedor N, Liao Z, Alemany S, Pedersen CT, Fernandez-Jimenez N, Campbell ML, Girchenko P, Barthome E, Martin LC, Seelemeyer H, Kumar A, Jeanne A, Ahluwalia TS, Black MH, Buitelaar JK, Fisher SE, Heiskala A, Hernández-Lorca M, Jaddoe VW, Järvelin MR, Koopowitz SM, Lake MT, Lichtenstein P, Llop S, Luo M, Malmberg A, Marí S, Oldehinkel AJ, Pausova Z, Pennell CE, Plomin R, Reichborn-Kjennerud T, Reilly S, Rodriguez A, Rolland T, Ronald A, Räikkönen K, Shin J, Artigas MS, Tate AE, Tiemeier H, Verhoef E, Vuoksimaa E, Wake M, Warrier V, Ystrom E, Bölte S, Ecker C, Bourgeron T, Lahti J, Stein DJ, Bilbao JR, Bønnelykke K, Bustamante M, Paus T, Middeldorp CM, Sunyer J, Sebert S, Standl M, Whitehouse AJO, Kaprio J, Ramos-Quiroga JA, Ribases M, Casas M, Bosch R, Morgan AT, Vrijkotte TGM, Larsson H, Cecil CAM, Hartman CA, Boomsma DI, Rimfeld K, Havdahl A, St Pourcain B. Nat Hum Behav 2026 Sep 21

  PMID: 42768150

• Preconception and Early-Pregnancy Alcohol Consumption in Women and Men, Infertility and Risk for Miscarriage.

  Martinez Mayans M, Lin CHX, Boxem AJ, Van Brienen CP, Mulders AGMGJ, Gaillard R, Jaddoe VWV. Nutrients 2026 Sep 09

  PMID: 42796937

• Early-life primary prevention of childhood asthma.

  Jaddoe VWV, Duijts L. Lancet 2026 Sep 19

  PMID: 42705252

• Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressure.

  Xie T, Ani A, Vaez A, Nolte IM, Su S, Ishikuro M, Wang S, Zhang W, Soares AG, Motazedi E, Calas L, Ronkainen J, Pedersen CT, Lu X, Stinson SE, Felix JF, Stankevic E, Wang CA, Thiering E, Fernández D, Calvo-Serra B, Stathopoulou MG, Fore R, Kumar A, Tuhkanen J, Bilbao JR, Ibarluzea J, Isaacs A, Fonvig CE, Rivadeneira F, Lund MAV, Holm LA, van der Most PJ, Riese H, Narita A, Tamiya G, Flexeder C, Wiersma R, Argoty-Pantoja AD, Vinding R, Hansen TW, Kümler T, Estarlich M, Bustamante M, Yuan WL, Boland-Augé A, Deleuze JF, Petrelis AM, Rifas-Shiman S, Kajantie E, Fernandez-Jimenez N, Santa-Marina L, Arts ICW, Lahti J, Strandberg T, Kull I, Bergström A, Hivert MF, Bønnelykke K, Kuriyama S, Beilin LJ, Mori TA, Hartman CA, Grarup N, Thijs C, Räikkönen K, Melén E, Oken E, Visvikis-Siest S, Gützkow KB, Grazuleviciene R, Heude B, Chatzi L, Vrijheid M, Standl M, Vrijkotte T, Pennell CE, Oldehinkel AJ, Hansen T, Jaddoe VWV, Holm JC, Sebert S, Timpson NJ, Obara T, Wang X, Lawlor DA, Corpeleijn E, Ahluwalia TS, Snieder H. Eur Heart J 2026 Sep 02

  PMID: 42036355