Tomotaka Ugai

Biography

Dr. Ugai is a junior faculty member at Brigham and Women's Hospital/Harvard Medical School and an MD/PhD physician scientist with expertise in pathology, clinical oncology, cancer epidemiology, and molecular epidemiology. His current research focuses on early-onset cancers and tumor biomarkers, including immune and microbial characteristics of cancer. Dr. Ugai is a founder of the International Cancer Spectrum Consortium, which is an interdisciplinary working group with faculty, postdocs, and students from various institutions all over the world. Dr. Ugai's group aims to build up a resource that integrates lifestyles and biomarkers including genetics and tissue molecular markers to (a) develop effective prevention and early-detection strategies, and (b) identify novel biomarkers to guide early-stage clinical decisions.

Awards and Honors

• AACR Scholar-in-Training Award for AACR Annual Meeting 2023, 2023
  American Association for Cancer Research
• Brigham and Women's Hospital Faculty Career Development Award, 2023
  Brigham and Women's Hospital
• MPE Rising Faculty Investigator Award, 2023
  The 6th International MPE Meeting
• Rose Traveling Fellowship Program in Chronic Disease Epidemiology and Biostatistics, 2022
  Harvard Th. Chan School of Public Health
• AACR Scholar-in-Training Award for AACR Special Conference: Colorectal Cancer, 2022
  American Association for Cancer Research
• Harvey V. Fineberg Fellowship in Cancer Prevention, 2022
  Harvard Th. Chan School of Public Health
• AACR Scholar-in-Training Award for AACR Annual Meeting 2022, 2022
  American Association for Cancer Research
• Japanese Cancer Association Young Investigator Award, 2021
  Japanese Cancer Association

Publications

• An Empirical Dietary Pattern Associated With the Gut Microbial Features in Relation to Colorectal Cancer Risk.

  Wang K, Lo CH, Mehta RS, Nguyen LH, Wang Y, Ma W, Ugai T, Kawamura H, Ugai S, Takashima Y, Mima K, Arima K, Okadome K, Giannakis M, Sears CL, Meyerhardt JA, Ng K, Segata N, Izard J, Rimm EB, Garrett WS, Huttenhower C, Giovannucci EL, Chan AT, Ogino S, Song M. Gastroenterology 2024

• Alcohol and colorectal cancer risk, subclassified by mutational signatures of DNA mismatch repair deficiency.

  Fang A, Ugai T, Gurjao C, Zhong R, Liu Z, Zhang X, Wang P, Nowak J, Wang M, Giannakis M, Ogino S, Zhang X, Giovannucci E. J Natl Cancer Inst 2024 Aug 01

• Risk of colorectal cancer and adenoma after an appendectomy: results from three large prospective cohort studies and meta-analysis.

  Zhang Y, Khil J, Feng X, Ugai T, Ogino S, Giovannucci E. Cancer Causes Control 2024

• Clinicopathological, molecular, and prognostic features of colorectal carcinomas with KRAS c.34G>T (p.G12C) mutation.

  Ugai S, Yao Q, Takashima Y, Zhong Y, Matsuda K, Kawamura H, Imamura Y, Okadome K, Mima K, Arima K, Kosumi K, Song M, Meyerhardt JA, Giannakis M, Nowak JA, Ugai T, Ogino S. Cancer Sci 2024

• Addressing the Rising Trend in Early-Age-Onset Cancers in Canada.

  Wildgoose P, Servidio-Italiano F, Raphael MJ, Slovinec D'Angelo M, Macaulay C, Kassam S, Nixon N, Perea J, Hamilton S, Ramjeesingh R, Gill S, Pollett A, Ogino S, Ugai T, Gupta A. Curr Oncol 2024 Jul 19