Tamar Sofer

Related Links

Biography

I am a biostatistical researcher focusing on genetic and omics analyses of diverse and complex populations. I did my PhD in Biostatistics at the Harvard T.H. Chan School of Public Health, and graduated at 2012. Then, I continued as a postdoctoral fellow there, and later became a research scientist at the Genetic Analysis Center at the University of Washington in Seattle. At UW, I worked on genetic association analyses in the Hispanic Community Health Study/Study of Latinos, and on analysis of whole genome sequencing data from the NHLBI's Trans-Omics in Precision Medicine initiative. In late 2017 I moved to BWH and Harvard University, where I continue to develop and implement methodology for genetic and omics analyses of sleep , cognitive, cardiopulmonary, and metabolic phenotypes, with the goal of understanding the genetic basis of such phenotypes, and how environmental exposures modify the pathways from genotypes to phenotypes. I extensively collaborate with minority population studies such as the Hispanic Community Health Study/Study of Latinos, the Multi-Ethnic Study of Atherosclerosis, the Jackson Heart Study, and more.

Education and Training

• BSc, Mathematics
  The Hebrew University of Jerusalem
• PhD, Biostatistics
  Harvard University

Publications

• Association between Accelerometer-Measured Irregular Sleep Duration and Longitudinal Changes in Body Mass Index in Older Adults.

  Kianersi S, Potts KS, Wang H, Sofer T, Noordam R, Rutter MK, Redline S, Huang T. medRxiv 2024 Nov 01

• Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas.

  Borda V, Loesch DP, Guo B, Laboulaye R, Veliz-Otani D, French JN, Leal TP, Gogarten SM, Ikpe S, Gouveia MH, Mendes M, Abecasis GR, Alvim I, Arboleda-Bustos CE, Arboleda G, Arboleda H, Barreto ML, Barwick L, Bezzera MA, Blangero J, Borges V, Caceres O, Cai J, Chana-Cuevas P, Chen Z, Custer B, Dean M, Dinardo C, Domingos I, Duggirala R, Dieguez E, Fernandez W, Ferraz HB, Gilliland F, Guio H, Horta B, Curran JE, Johnsen JM, Kaplan RC, Kelly S, Kenny EE, Konkle BA, Kooperberg C, Lescano A, Lima-Costa MF, Loos RJF, Manichaikul A, Meyers DA, Naslavsky MS, Nickerson DA, North KE, Padilla C, Preuss M, Raggio V, Reiner AP, Rich SS, Rieder CR, Rienstra M, Rotter JI, Rundek T, Sacco RL, Sanchez C, Sankaran VG, Santos-Lobato BL, Schumacher-Schuh AF, Scliar MO, Silverman EK, Sofer T, Lasky-Su J, Tumas V, Weiss ST, Mata IF, Hernandez RD, Tarazona-Santos E, O'Connor TD. Cell Genom 2024 Nov 13

• Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review.

  Rao H, Weiss MC, Moon JY, Perreira KM, Daviglus ML, Kaplan R, North KE, Argos M, Fernández-Rhodes L, Sofer T. HGG Adv 2024 Oct 29

• Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea Subtype.

  Nagarajan P, Kurniansyah N, Lee J, Gharib SA, Xu Y, Zhang Y, Spitzer B, Faquih T, Zhou H, Boerwinkle E, Chen H, Gottlieb DJ, Guo X, Heard-Costa NL, Hidalgo BA, Levy D, Liu PY, Mei H, Montalvan R, Mukherjee S, North KE, O'Conner GT, Palmer LJ, Patel SR, Psaty BM, Purcell SM, Raffield LM, Rich SS, Rotter JI, Saxena R, Smith AV, Stone KL, Zhu X, Cade BE, Sofer T, Redline S, Wang H. medRxiv 2024 Oct 28

• Differential prediction performance between Caribbean- and Mainland-subgroups using state-of-the-art polygenic risk scores for coronary heart disease: Findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

  Hutten CG, Boehm FJ, Smith JA, Spitzer BW, Wassertheil-Smoller S, Isasi CR, Cai J, Unkart JT, Sun J, Persky V, Daviglus ML, Sofer T, Argos M. medRxiv 2024 Sep 27