Shijun Deng

Biography

Publications

• Platelet integrin aIIbß3 plays a key role in a venous thrombogenesis mouse model.

  Adair BD, Field CO, Alonso JL, Xiong JP, Deng SX, Ahn HS, Mashin E, Clish CB, van Agthoven J, Yeager M, Guo Y, Tess DA, Landry DW, Poncz M, Arnaout MA. Nat Commun 2024 10 04

  PMID: 39366965

• Endogenous p53 inhibitor TIRR dissociates systemic metabolic health from oncogenic activity.

  Tsaousidou E, Chrzanowski J, Drané P, Lee GY, Bahour N, Wang ZB, Deng S, Cao Z, Huang K, He Y, Kaminski M, Michalek D, Güney E, Parmar K, Fendler W, Chowdhury D, Hotamisligil GS. Cell Rep 2024 06 25

  PMID: 38861384

• Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9 is dependent on cargo receptor protein Surf4.

  Wang B, Shen Y, Zhai L, Xia X, Gu HM, Wang M, Zhao Y, Chang X, Alabi A, Xing S, Deng S, Liu B, Wang G, Qin S, Zhang DW. J Lipid Res 2026

  PMID: 34118252

• Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis.

  Alabi A, Xia XD, Gu HM, Wang F, Deng SJ, Yang N, Adijiang A, Douglas DN, Kneteman NM, Xue Y, Chen L, Qin S, Wang G, Zhang DW. Nat Commun 2021 03 25

  PMID: 33767172

• The role of the C-terminal domain of PCSK9 and SEC24 isoforms in PCSK9 secretion.

  Deng SJ, Shen Y, Gu HM, Guo S, Wu SR, Zhang DW. Biochim Biophys Acta Mol Cell Biol Lipids 2020 06

  PMID: 32058034