Ralph Mazitschek

Assistant Professor in the Department of Immunology and Infectious Diseases

Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health

Departments

Department of Immunology and Infectious Diseases

Other Positions

Assistant Professor of Radiology

Radiology-Massachusetts General Hospital, Harvard Medical School

Biography

What is chemical biology?

Antolin AA, Aye Y, Bar-Peled L, De Vita E, Dudkina N, Jewett MC, Kiely-Collins H, Mazitschek R, Zhang ZJ. Cell Chem Biol 2024 Sep 19
Identification of a Polypeptide Inhibitor of O-GlcNAc Transferase with Picomolar Affinity.

Hammel FA, Payne NC, Marando VM, Mazitschek R, Walker S. J Am Chem Soc 2024 Sep 25
Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology.

Payne NC, Ichikawa S, Woo CM, Mazitschek R. STAR Protoc 2024 Jun 21
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes.

Xie X, Zhang O, Yeo MJR, Lee C, Harry SA, Paul L, Li Y, Payne NC, Nam E, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB. bioRxiv 2024 May 14
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.

Yeo MJ, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N. bioRxiv 2024 May 14

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