Nancy Mueller

Biography

Research

There is evidence that under certain conditions, viral and other infections play an integral role in carcinogenesis. These infections establish latency or are chronic; age and severity of infection are generally risk factors for malignancy. Understanding the natural history of such infections and identification of the risk factors for malignancy may provide insight for intervention strategies.

Dr. Mueller's major research has been on the role of age at infection with the Epstein -Barr virus (EBV) on the pathogenesis of Hodgkin's lymphoma (HL). Her group conducted research on the natural history of the first identified human retrovirus, HTLV- I, and hepatitis C virus in longitudial studies of endemic villages in southern Japan.

Education and Training

• BA (cum laude), Biology
  Beloit College
• SM, Epidemiology
  Harvard School of Public Health
• SD, Epidemiology
  Harvard School of Public Health

Publications

• Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine.

  Falsey AR, Sobieszczyk ME, Hirsch I, Sproule S, Robb ML, Corey L, Neuzil KM, Hahn W, Hunt J, Mulligan MJ, McEvoy C, DeJesus E, Hassman M, Little SJ, Pahud BA, Durbin A, Pickrell P, Daar ES, Bush L, Solis J, Carr QO, Oyedele T, Buchbinder S, Cowden J, Vargas SL, Guerreros Benavides A, Call R, Keefer MC, Kirkpatrick BD, Pullman J, Tong T, Brewinski Isaacs M, Benkeser D, Janes HE, Nason MC, Green JA, Kelly EJ, Maaske J, Mueller N, Shoemaker K, Takas T, Marshall RP, Pangalos MN, Villafana T, Gonzalez-Lopez A. N Engl J Med 2021 12 16

• Elevated Serum Levels of sCD30 and IL6 and Detectable IL10 Precede Classical Hodgkin Lymphoma Diagnosis.

  Levin LI, Breen EC, Birmann BM, Batista JL, Magpantay LI, Li Y, Ambinder RF, Mueller NE, Martínez-Maza O. Cancer Epidemiol Biomarkers Prev 2017 07

• Dietary pattern and risk of hodgkin lymphoma in a population-based case-control study.

  Epstein MM, Chang ET, Zhang Y, Fung TT, Batista JL, Ambinder RF, Zheng T, Mueller NE, Birmann BM. Am J Epidemiol 2015 Sep 01

• Serum IgA to Epstein-Barr virus early antigen-diffuse identifies Hodgkin's lymphoma.

  McAllister SC, Shedd D, Mueller NE, Chang ET, Miller G, Bhaduri-McIntosh S. J Med Virol 2014

• Atypical prediagnosis Epstein-Barr virus serology restricted to EBV-positive Hodgkin lymphoma.

  Levin LI, Chang ET, Ambinder RF, Lennette ET, Rubertone MV, Mann RB, Borowitz M, Weir EG, Abbondanzo SL, Mueller NE. Blood 2012 Nov 01