Michael Chao

Biography

Education and Training

• BS, Biological Sciences
  Cornell University
• PhD, Biological and biomedical sciences
  Harvard University

Publications

• Complete genome sequence of a virulent barcoded Mycobacterium tuberculosis str. Erdman commonly used for non-human primate infection studies.

  Marin MG, Chase MR, Quinones N, Wakabayashi S, Mugahid D, Fortune SM, Farhat MR, Chao MC. Microbiol Resour Announc 2025 Mar 11

  PMID: 39964179

• Intravenous BCG-mediated protection against tuberculosis requires CD4+ T cells and CD8a+ lymphocytes.

  Simonson AW, Zeppa JJ, Bucsan AN, Chao MC, Pokkali S, Hopkins F, Chase MR, Vickers AJ, Sutton MS, Winchell CG, Myers AJ, Ameel CL, Kelly RJ, Krouse B, Hood LE, Li J, Lehman CC, Kamath M, Tomko J, Rodgers MA, Donlan R, Chishti H, Borish HJ, Klein E, Scanga CA, Fortune SM, Lin PL, Maiello P, Roederer M, Darrah PA, Seder RA, Flynn JL. J Exp Med 2025 Apr 07

  PMID: 39912921

• Markov field network model of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques.

  Wang S, Myers AJ, Irvine EB, Wang C, Maiello P, Rodgers MA, Tomko J, Kracinovsky K, Borish HJ, Chao MC, Mugahid D, Darrah PA, Seder RA, Roederer M, Scanga CA, Lin PL, Alter G, Fortune SM, Flynn JL, Lauffenburger DA. Cell Syst 2024 Dec 18

  PMID: 39504969

• Vaginal lactobacilli produce anti-inflammatory ß-carboline compounds.

  Glick VJ, Webber CA, Simmons LE, Martin MC, Ahmad M, Kim CH, Adams AND, Bang S, Chao MC, Howard NC, Fortune SM, Verma M, Jost M, Beura LK, James MJ, Lee SY, Mitchell CM, Clardy J, Kim KH, Gopinath S. Cell Host Microbe 2024 Nov 13

  PMID: 39423813

• Targeted protein degradation in mycobacteria uncovers antibacterial effects and potentiates antibiotic efficacy.

  Won HI, Zinga S, Kandror O, Akopian T, Wolf ID, Schweber JTP, Schmid EW, Chao MC, Waldor M, Rubin EJ, Zhu J. Nat Commun 2024 May 14

  PMID: 38744895