Luca Pinello

Instructor

Biostatistics, Harvard T.H. Chan School of Public Health

Departments

Department of Biostatistics

Other Positions

Associate Professor of Pathology

Pathology-Massachusetts General Hospital, Harvard Medical School

Biography

Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations.

Lederer AR, Leonardi M, Talamanca L, Bobrovskiy DM, Herrera A, Droin C, Khven I, Carvalho HJF, Valente A, Dominguez Mantes A, Mulet Arabí P, Pinello L, Naef F, La Manno G. Nat Methods 2024
Selective Enhancer Gain of Function Deregulates MYC Expression in Multiple Myeloma.

Rahmat M, Clement K, Alberge JB, Sklavenitis-Pistofidis R, Kodgule R, Fulco CP, Heilpern-Mallory D, Nilsson K, Dorfman D, Engreitz JM, Getz G, Pinello L, Ryan R, Ghobrial IM. Cancer Res 2024 Sep 23
CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing.

Becerra B, Wittibschlager S, Patel ZM, Kutschat AP, Delano J, Che E, Karjalainen A, Wu T, Starrs M, Jankowiak M, Bauer DE, Seruggia D, Pinello L. bioRxiv 2024 Sep 09
EPInformer: a scalable deep learning framework for gene expression prediction by integrating promoter-enhancer sequences with multimodal epigenomic data.

Lin J, Luo R, Pinello L. bioRxiv 2024 Aug 01
Scalable assessment of genome editing off-targets associated with genetic variants.

Lin J, Nguyen MA, Lin LY, Zeng J, Verma A, Neri NR, da Silva LF, Mucci A, Wolfe S, Shaw KL, Clement K, Brendel C, Pinello L, Pellin D, Bauer DE. bioRxiv 2024 Jul 25

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