Lorenzo Trippa

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Biography

I am interested in the development of adaptive clinical trial designs. My research includes the study of algorithms and methodologies for the analysis of data generated by adaptive trials. I am also particularly interested in Bayesian nonparametrics, a great source of modeling opportunity in biomedical applications as well as, both computational and theoretical problems.

Publications

• Informative censoring in externally controlled clinical trials: a potential source of bias.

  Rudra Gupta T, Schwartz DE, Saha R, Wen PY, Rahman R, Trippa L. ESMO Open 2025

• Deeper response predicts better outcomes in high-risk-smoldering-myeloma: results of the I-PRISM phase II clinical trial.

  Nadeem O, Aranha MP, Redd R, Timonian M, Magidson S, Lightbody ED, Alberge JB, Bertamini L, Dutta AK, El-Khoury H, Bustoros M, Laubach JP, Bianchi G, O'Donnell E, Wu T, Tsuji J, Anderson KC, Getz G, Trippa L, Richardson PG, Sklavenitis-Pistofidis R, Ghobrial IM. Nat Commun 2025 Jan 03

• Serum free light chains in a racially diverse population including African Americans and populations from South Africa.

  Bertamini L, Alberge JB, Lee DJ, El-Khoury H, Kim S, Fleming G, Murphy CSM, Colchie J, Davis MI, Perry J, Lightbody ED, Allam S, Goqwana LN, Philip V, Smyth NA, Sakrikar D, Perkins MC, Harding S, Troske D, Getz G, Karlson EW, Munshi NC, Anderson KC, Trippa L, Marinac CR, Chen WC, Joffe M, Ghobrial IM. Blood 2024 Nov 21

• Toxicity Adaptive Lists Design: A Practical Design for Phase I Drug Combination Trials in Oncology.

  Russo M, Mariani F, Cleary JM, Shapiro GI, Coté GM, Trippa L. JCO Precis Oncol 2024

• Unleashing the power of clinical trial data: a proposal for enhancing informed consent and data sharing.

  Trippa L, Khozin S. Oncologist 2024 Aug 05