Krystle Kalafut

Biography

Publications

• AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth.

  Cormerais Y, Lapp SC, Kalafut KC, Cissé MY, Shin J, Stefadu B, Personnaz J, Schrotter S, D'Amore A, Martin ER, Salussolia CL, Sahin M, Menon S, Byles V, Manning BD. bioRxiv 2024 Sep 23

• mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species.

  Hosios AM, Wilkinson ME, McNamara MC, Kalafut KC, Torrence ME, Asara JM, Manning BD. Nat Metab 2022 12

• Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization.

  MacArthur MR, Mitchell SJ, Chadaideh KS, Treviño-Villarreal JH, Jung J, Kalafut KC, Reynolds JS, Mann CG, Trocha KM, Tao M, Aye Cho TZ, Koontanatechanon A, Yeliseyev V, Bry L, Longchamp A, Ozaki CK, Lewis CA, Carmody RN, Mitchell JR. Cell Rep 2022 08 16

• Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice.

  Bernier M, Enamorado IN, Gómez-Cabrera MC, Calvo-Rubio M, González-Reyes JA, Price NL, Cortés-Rodríguez AB, Rodríguez-Aguilera JC, Rodríguez-López S, Mitchell SJ, Murt KN, Kalafut K, Williams KM, Ward CW, Stains JP, Brea-Calvo G, Villalba JM, Cortassa S, Aon MA, de Cabo R. NPJ Aging 2022 Jun 27

• Short-Term Ketogenic Diet Induces a Molecular Response That Is Distinct From Dietary Protein Restriction.

  Kalafut KC, Mitchell SJ, MacArthur MR, Mitchell JR. Front Nutr 2025