Gerald L. Chan

Biography

Publications

• IL-1Ra protects hematopoietic cells from chemotoxicity through p53-induced quiescence.

  Ye H, Qian L, Zhu S, Deng S, Wang X, Zhu J, Chan GL, Yu Y, Han W. FASEB J 2019 11

  PMID: 31373847

• Progranulin Recruits HSP70 to ß-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease.

  Jian J, Tian QY, Hettinghouse A, Zhao S, Liu H, Wei J, Grunig G, Zhang W, Setchell KDR, Sun Y, Overkleeft HS, Chan GL, Liu CJ. EBioMedicine 2016

  PMID: 27789271

• Association Between Progranulin and Gaucher Disease.

  Jian J, Zhao S, Tian QY, Liu H, Zhao Y, Chen WC, Grunig G, Torres PA, Wang BC, Zeng B, Pastores G, Tang W, Sun Y, Grabowski GA, Kong MX, Wang G, Chen Y, Liang F, Overkleeft HS, Saunders-Pullman R, Chan GL, Liu CJ. EBioMedicine 2016

  PMID: 27515686

• Selective protection of normal cells during chemotherapy by RY4 peptides.

  Wu XR, Liu L, Zhang ZF, Zhang B, Sun H, Chan GL, Li N. Mol Cancer Res 2014

  PMID: 24874433

• IL-1Ra selectively protects intestinal crypt epithelial cells, but not tumor cells, from chemotoxicity via p53-mediated upregulation of p21(WAF1) and p27(KIP1.).

  Wang X, Zhu S, Qian L, Gao J, Wu M, Gao J, Zhang Y, Chan GL, Yu Y, Han W. Pharmacol Res 2014

  PMID: 24681512