Alan Cowman

Biography

Publications

• PTRAMP, CSS and Ripr form a conserved complex required for merozoite invasion of Plasmodium species into erythrocytes.

  Cowman A, Seager B, Lim P, Lai KH, Feufack-Donfack L, Dass S, Xiao X, Jung N, Abraham A, Grigg M, Anstey N, William T, Sattabongkot J, Leis A, Longley R, Duraisingh M, Popovici J, Wilson D, Scally S. Res Sq 2025 Apr 28

  PMID: 40343341

• Optimization and Characterization of N-Acetamide Indoles as Antimalarials That Target PfATP4.

  Awalt JK, Ooi ZK, Ashton TD, Mansouri M, Calic PPS, Zhou Q, Vasanthan S, Lee S, Loi K, Jarman KE, Penington JS, Qiu D, Zhang X, Lehane AM, Mao EY, Gancheva MR, Wilson DW, Giannangelo C, MacRaild CA, Creek DJ, Yeo T, Sheth T, Fidock DA, Churchyard A, Baum J, Famodimu MT, Delves MJ, Kristan M, Stewart L, Sutherland CJ, Coyle R, Jagoe H, Lee MCS, Chowdury M, de Koning-Ward TF, Baud D, Brand S, Jackson PF, Cowman AF, Dans MG, Sleebs BE. J Med Chem 2025 Apr 24

  PMID: 40228810

• PTRAMP, CSS and Ripr form a conserved complex required for merozoite invasion of Plasmodium species into erythrocytes.

  Seager BA, Lim PS, Lai KH, Feufack-Donfack LB, Dass S, Xiao X, Jung NC, Abraham A, Grigg MJ, Anstey NM, William T, Sattabongkot J, Leis A, Longley RJ, Duraisingh MT, Popovici J, Wilson DW, Scally SW, Cowman AF. bioRxiv 2025 Mar 25

  PMID: 40196582

• Structure-activity analysis of imino-pyrimidinone-fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors.

  Hodder AN, Sleebs BE, Adams G, Rezazadeh S, Ngo A, Jarman K, Scally S, Czabotar P, Wang H, McCauley JA, Olsen DB, Cowman AF. FEBS J 2025 Mar 04

  PMID: 40035447

• Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.

  Ashton TD, Calic PPS, Dans MG, Kang Ooi Z, Zhou Q, Loi K, Jarman KE, Palandri J, Qiu D, Lehane AM, Maity B, De N, Famodimu MT, Delves MJ, Mao EY, Gancheva MR, Wilson DW, Chowdury M, de Koning-Ward TF, Baud D, Brand S, Jackson PF, Cowman AF, Sleebs BE. ChemMedChem 2024 Dec 16

  PMID: 39210733