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Summary

AI is reshaping industries, with Large Language Models and Generative AI poised to revolutionize health care. Responsible AI for Health Care: Concepts and Applications introduces these technologies’ core principles, emphasizing responsible AI use, ethical considerations, and safety measures under the tutelage of distinguished Harvard faculty. It transitions health care professionals from traditional to data-driven AI-augmented practices using a “zero-to-AI” strategy, providing foundational concepts tailored for health care applications. 

Participants will engage in a dynamic learning experience through group discussions, active learning, case studies, and master classes that explore AI’s origins and implementation challenges. The course examines viable business models for AI in health care and forecasts future developments over the next five years. It also fosters a networking environment for collaboration among participants, serving as a lasting resource beyond the program. 

Program Overview

AI is Transforming Industries—Understand its Role in Healthcare’s Future

Large Language Models (LLMs), machine learning, and other forms of artificial intelligence (AI) are reshaping how healthcare is delivered, managed, and regulated. But with this promise comes complexity and risk. Responsible AI for Health Care: Concepts and Applications is a four-day, intensive live online program that equips healthcare professionals with the knowledge and tools to critically assess, implement, and govern AI technologies in clinical, operational, and public health settings. 

Led by renowned Harvard faculty and AI ethics experts, this program focuses on ethical principles, regulatory frameworks, fairness, transparency, and implementation science. Participants will examine real-world case studies—both successes and failures—to explore how to apply responsible AI in high-stakes environments while avoiding unintended harms. 

Through interactive lectures, group discussion, and applied learning, participants will engage with timely questions at the intersection of innovation, safety, and health equity. The program also fosters a strong peer network, designed to support continued learning and collaboration well beyond the course. 

Harvard Chan School invites you to learn more about our AI in Health Care Certificate of Specialization program. While each program can be taken independently, completing three healthcare AI courses in our portfolio earns the Certificate of Specialization.

For those who have taken earlier versions of Applied AI in Health Care, this updated program reflects the latest developments in AI for healthcare, with fresh group projects and collaborative learning opportunities. For any questions about the programs or Certificate of Specialization, please email enrollment@hsph.harvard.edu.

See Our Faculty in Action

In the video below, you can hear directly from course faculty on how AI is reshaping healthcare operations and patient care. This discussion offers a preview of the key concepts and case studies you’ll explore more deeply in this program.

Certificate of Specialization

Advance your Career with a Certificate of Specialization

This program contributes to the AI in Health Care Certificate of Specialization.  Click here for more information. 

Objectives & Highlights

  • Define foundational AI concepts and differentiate types of AI tools relevant to clinical, operational, and population health use cases 
  • Identify sources of algorithmic bias stemming from data, design, or deployment, and evaluate their impact on health equity 
  • Apply leading ethical frameworks to assess fairness, transparency, accountability, and safety in healthcare AI 
  • Compare and contrast U.S. and global regulatory approaches to healthcare AI, and assess implications for compliance and innovation 
  • Evaluate the trade-offs between explainability and model complexity, and explain the role of transparency in building trust in clinical AI 
  • Assess post-deployment risks and accountability mechanisms, including model drift, adverse event reporting, and human oversight 
  • Analyze real-world AI successes and failures to identify lessons learned and implementation challenges 
  • Develop strategies for responsible AI implementation aligned with ethical standards, clinical workflows, and organizational readiness
  • Led by Harvard faculty with deep expertise in AI, ethics, regulation, and healthcare implementation 
  • Explore real-world case studies of both successful and flawed AI implementations 
  • Engage with ethical and regulatory frameworks shaping AI in healthcare globally 
  • Gain tools to evaluate and monitor AI systems, including bias detection, transparency practices, and risk assessments 
  • Participate in interactive learning through group discussion, applied exercises, and optional Q&A 
  • Develop strategies for responsible AI implementation aligned with clinical, regulatory, and organizational realities 
  • Join a global network of healthcare professionals committed to safe, equitable, and effective AI 

Tackling AI Challenges in Healthcare: 

  • Diagnosis
    Responsible AI leverages large-scale multimodal health data to enhance diagnostic accuracy, reduce misdiagnosis, and ease clinician workload, all while prioritizing ethical data use and patient privacy.
  • Precision Medicine
    By enabling data-driven, patient-specific treatment plans, responsible AI shifts care from generic protocols to personalized medicine. This approach improves outcomes, optimizes resource use, and ensures equity through bias-aware, ethical design.
  • Prediction Models
    Ethical AI-powered prediction models support clinicians in forecasting disease progression and tailoring interventions. These models enhance decision-making, reduce risks, and promote transparent, accountable care strategies.
  • Course Focus
    To unlock AI’s full potential and prevent harm, practitioners must understand the responsibilities that extend beyond algorithm development. This course emphasizes pre- and post-deployment considerations, including algorithmic bias, equity, and public health impacts. Students will gain the tools to implement responsible AI solutions that improve patient outcomes and drive systemic efficiency.

Throughout this program, you’ll learn directly from distinguished Harvard faculty and leading industry experts. Interactive live sessions and small group discussions provide plenty of opportunities to ask questions and exchange experiences with faculty. Core instructors include:

  • Trishan Panch, MD, MPH: Instructor, Harvard T.H. Chan School of Public Health
  • Heather Mattie, PhD, SM, MS: Lecturer, Co-Director, Health Data Science Master’s Program, Director of EDIB Programs, Harvard T.H. Chan School of Public Health
  • John Brownstein: Chief Innovation Officer, Boston Children’s Hospital. Professor of Pediatrics, Harvard Medical School
  • Ray Campbell: President, FAIR Health
  • Lindsay Jubelt: Chief Clinical Officer, Optum
  • Emily Lindemer, PhD: VP Data & Healthcare Innovation, Morgan Health – JP Morgan Chase
  • Gianluca Mauro: CEO, AI Academy
  • Santiago Romero-Brufau, MD, PhD: Director of AI and Systems Engineering, Mayo Clinic. Adjunct Assistant Professor, Harvard T.H. Chan School of Public Health

Frequently Asked Questions

Responsible AI for Health Care: Concepts and Applications is a live online program from Harvard T.H. Chan School of Public Health Executive and Continuing Education designed for healthcare professionals who want to understand and apply artificial intelligence responsibly in their organizations. 

Over four days, you will explore AI fundamentals, ethical frameworks, regulatory guidance, and real-world case studies to evaluate and implement AI solutions in clinical, operational, and public health settings. The course emphasizes interactive discussion and applied learning so participants can immediately apply insights to their organizations. 

This online program is designed for senior managers, clinicians, and executives from sectors such as healthcare delivery, healthcare technology, primary care systems, payers, and governments. Healthcare professionals across the U.S. and internationally have found the program immensely valuable. 

This program is right for you if you are responsible for decisions around innovation, data, or technology in healthcare organizations, or want to be responsible for such decisions.  

You will gain practical tools to: 

  • Understand foundational AI concepts tailored to healthcare settings 
  • Implement responsible AI strategies in clinical and public health contexts 
  • Identify and reduce algorithmic bias 
  • Apply ethical and regulatory frameworks 
  • Evaluate AI risks, transparency, and compliance 

The full agenda is available here

No. The program is accessible to professionals from clinical, policy, and administrative roles. The focus is on ethical implementation, decision-making, and leadership, tailored to healthcare and public health settings—not programming. 

Becoming an AI leader in healthcare requires a blend of ethical, technical, and strategic skills. You can build this expertise by gaining a solid understanding of artificial intelligence and studying frameworks for fairness, governance, and regulatory compliance. Programs like Harvard T.H. Chan School of Public Health’s Responsible AI for Health Care program can help you move from awareness to leadership—equipping you with the confidence and knowledge to guide AI strategy, oversight, and innovation across health systems. 

While on-the-job experience with AI is very valuable, it often lacks the structured frameworks, ethical grounding, and cross-sector perspectives needed to lead AI responsibly in healthcare. The Responsible AI for Health Care program from Harvard T.H. Chan School of Public Health Executive Education offers structured learning guided by Harvard faculty and enriched by peers from diverse disciplines. Through interactive discussions and real-world case studies, you’ll explore what has worked (and what hasn’t) in different organizations. This shared learning helps you return to your own workplace with proven strategies, practical insights, and a stronger foundation for responsible AI implementation. 

You’ll learn from Harvard faculty, healthcare leaders, and industry experts, including: 

  • Program DirectorTrishan Panch – CEO, LUNRStudio; Executive Chair and Chief Strategy Officer, Lumin Health; Co-founder, Wellframe 
  • Program Director: Heather Mattie – Lecturer on Biostatistics, Co-Director of the Health Data Science Master’s Program, Director of EDIB Programs at Harvard Chan School 
  • Santiago Romero-Brufau – Director of AI and Systems Engineering, Department of Otolaryngology — Head and Neck Surgery, Mayo Clinic 

Note: This list may not include all faculty and is subject to change. 

This course is part of the Harvard T. H. Chan School of Public Health’s Executive Education AI in Health Care Certificate of Specialization. Completing this and two other AI courses (Innovation with AI in Health Care and Implementing Health Care AI in Clinical Practice) earns the certificate, showing advanced skills in healthcare AI leadership. 

All individual Harvard Chan Executive Education programs also award a Certificate of Participation upon completion. 

Note: If you have previously completed a healthcare AI course at Harvard Chan School, or enroll in Responsible AI for Healthcare in February 2026, you will be eligible to earn the Certificate of Specialization with 2 courses, per the prior criteria. 

Yes, we offer customized programs for organizations that can be adapted from open-enrollment courses like Responsible AI for Health Care or designed as a new, bespoke program

  • Teams of 4–20: We can offer a discounted cohort of an existing open enrollment program to accommodate your group. 
  • Teams of 21+ : We recommend a fully customized design—either a modified version of an existing course or a new program built around your goals. 

We’d be happy to have an informal conversation about how we can help you to customize your organizational training needs.  Please contact Priya Ponnappan for more information at Priya_ponnappan@hsph.harvard.edu 

Advance Your Career at Harvard with Responsible AI for Health Care: Concepts and Applications