Jessica Paulus, ScD, BA
Biography
Jess Paulus, is Senior Director of Real World Research and leads a team of scientists with expertise
in the designs and methods specific to leveraging real-world data networks to meaningfully inform
clinical and regulatory decision making. Dr. Paulus provides senior scientific oversight regarding
study design, analytic approaches, and dissemination strategies for RWD-based studies.
Prior to joining Ontada, Dr. Paulus was faculty at Tufts Medical School for over a decade, where she
served as Research Director of the Tufts Predictive Analytics and Comparative Effectiveness Center
and Associate Director of the Clinical and Translational Science MS/PhD Graduate Program. At
Tufts, she led the conduct of federally-funded studies related to methods development in areas
including comparative effectiveness research, clinical prediction models and heterogeneity of
treatment effect. She also served on the faculty of the Harvard T.H. Chan School of Public Health and
the Heller School at Brandeis University.
Dr. Paulus graduated magna cum laude from Haverford College and received a doctorate in
Epidemiology from Harvard T.H. Chan School of Public Health, where she focused on epidemiologic
methods for the study of chronic disease using observational data. She remains engaged in teaching
epidemiologic and RWD-methods as adjunct faculty at Tufts and as a lecturer at Harvard Medical
School