A new article published in Nature Mental Health used FEP-CAUSAL Collaboration data to examine comparative effectiveness of antipsychotic medications after first-episode psychosis.
The study used two target trials with different timeframes to examine relapse and hospitalization risk for patients who switched to long-acting injectable (LAI) medications versus those who remained on oral antipsychotics following first episode psychosis (FEP).
Researchers found little impact of long-acting injectable (LAI) therapies on hospitalization risk in the 18 months following first-episode psychosis. However, 3-year psychotic relapse risk indicated that long-acting injectable (LAI) medications may reduce relapse and have increased benefits in vulnerable patient subgroups.
CAUSALab researchers include Alejandro Szmulewicz, Gonzalo Martínez-Alés, Roger Logan, Miguel Hernán.
Read the Nature Mental Health article now.
