Ana Arruda

Biography

Publications

• CaMKIIß Ca2+ptures ER signals to initiate autophagosome biogenesis.

  Artico LL, Arruda AP. Mol Cell 2025 Feb 06

  PMID: 39919714

• CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.

  Mathiowetz AJ, Meymand ES, Deol KK, Parlakgül G, Lange M, Pang SP, Roberts MA, Torres EF, Jorgens DM, Zalpuri R, Kang M, Boone C, Zhang Y, Morgens DW, Tso E, Zhou Y, Talukdar S, Levine TP, Ku G, Arruda AP, Olzmann JA. bioRxiv 2024 Jun 08

  PMID: 38895340

• Sterol O-acyltransferase (SOAT/ACAT) activity is required to form cholesterol crystals in hepatocyte lipid droplets.

  Bairos JA, Njoku U, Zafar M, Akl MG, Li L, Parlakgul G, Arruda AP, Widenmaier SB. Biochim Biophys Acta Mol Cell Biol Lipids 2024

  PMID: 38761895

• Spatial mapping of hepatic ER and mitochondria architecture reveals zonated remodeling in fasting and obesity.

  Parlakgül G, Pang S, Artico LL, Min N, Cagampan E, Villa R, Goncalves RLS, Lee GY, Xu CS, Hotamisligil GS, Arruda AP. Nat Commun 2024 May 10

  PMID: 38729945

• Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis.

  Chang CF, Gunawan AL, Liparulo I, Zushin PH, Vitangcol K, Timblin GA, Saijo K, Wang B, Parlakgül G, Arruda AP, Stahl A. EMBO J 2024

  PMID: 38212382