Dan Chasman

Biography

Publications

• Co-occurring clonal hematopoiesis exhibits strong selection and high leukemia risk.

  Barnao KM, Hubbard AK, Chan ICC, Zhou W, Jakubek YA, Genovese G, Wong WSW, Kelly RL, Young CD, Brown DW, Huang WY, Freedman ND, Jones K, Hutchinson A, Hicks B, Tran D, Arnett D, Barnes KC, Bis JC, Boerwinkle E, Brody JA, Carson AP, Chasman DI, Cho MH, Desai P, Doyle MF, Fornage M, Guo X, Heard-Costa N, Irvin MR, Johnson AD, Kardia SLR, Kooperberg C, Levy D, Lewis JP, Li Y, Loos RJF, Mack TM, Mathias RA, Mitchell BD, North KE, Pankratz N, Peyser PA, Preuss MH, Psaty BM, Raffield LM, Redline S, Rich SS, Rotter JI, Silverman EK, Smith AV, Smith JA, Stilp A, Cao Y, Scheet P, Reiner AP, Bick AG, Chanock SJ, Auer PL, Bolton KL, Machiela MJ. Nat Commun 2026 May 21

  PMID: 42168198

• Rare coding variant architecture and gene discovery from 130,000 sequenced cases of atrial fibrillation.

  Jurgens SJ, Enzan N, Dinsmore IR, Choi SH, Luo J, Lipov A, Hartle C, Wang X, Marston NA, Weng LC, Melloni GE, Chalazan B, Gray MP, Pirruccello JP, Diaz A, Chaffin MD, Ornelas-Loredo A, Tang O, Darbar FA, Kany S, Chen Y, von Falkenhausen AS, Morrison AC, Natale A, Tveit A, Geelhoed B, Cade B, Van Wagoner DR, Haase D, Soliman EZ, Davogustto GE, Calkins H, Anderson JL, Brody JA, Barnard J, Hokanson JE, Smith JD, Bis JC, Young K, Johnson LS, Long L, Risch L, Gula LJ, Kwee LC, Kühne M, Preuss M, Gupta N, Nafissi NA, Smith NL, Nilsson PM, van der Harst P, Wells QS, Judy RL, Schnabel RB, Johnson R, Smit RA, Gabriel S, Knight S, Furukawa T, Min YI, Yoneda ZT, Laksman ZW, Alonso A, Psaty BM, Albert CM, Arking DE, Roden DM, Chasman DI, Rader DJ, Conen D, McManus DD, Fatkin D, Boerwinkle E, Marcus GM, Christophersen IE, Smith JG, Roberts JD, Raffield LM, Shoemaker MB, Cho MH, Cutler MJ, Chung MK, Olesen MS, Sinner MF, Sotoodehnia N, Kirchhof P, Loos RJ, Nazarian S, Mohanty S, Damrauer SM, Kaab S, Heckbert SR, Redline S, Shah SH, Tanaka T, Ebana Y, Lubitz SA, Lunetta KL, Benjamin EJ, Rienstra M, Figtree GA, Darbar D, Bezzina CR, Ruff CT, Sabatine MS, Mirshahi T, Ellinor PT. Res Sq 2026 May 04

  PMID: 42147184

• Genomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome.

  Moolhuijsen LME, Zhu J, Mullin BH, Pujol-Gualdo N, Actkins KV, Mack JA, Rao H, Trivedi B, Kentistou KA, Zhao Y, Westergaard D, Tyrmi JS, Thorleifsson G, Zhang Y, Wittemans L, DeVries A, Brewer K, Sisk R, Danning R, Preuss MH, Jones MR, Ruth KS, Andersen M, Azziz R, Banasik K, Boehnke M, Broer L, Brunak S, Chan YM, Chasman DI, Daly M, Ehrmann DA, Fauser BC, Fritsche LG, Hayes MG, He C, Huang H, Kowalska I, Kraft P, Legro RS, Lin N, Loos RJ, Louwers YV, Magi R, McCarthy MI, Morin-Papunen L, Morrison JV, Morton C, Nadkarni GN, Neale BM, Nielsen HS, Nyegaard M, Ostrowski SR, Pedersen OBV, Sørensen E, Mikkelsen C, Erikstrup C, Kaspersen KA, Bruun MT, Aagaard B, Ullum H, Obermayer-Pietsch B, Palotie A, Reeve MP, Salumets A, Saxena R, Spector TD, Stuckey BGA, Thorsteinsdottir U, Uitterlinden AG, Urbanek M, Zöllner S, van Heel DA, Hirschhorn JN, Stefansson K, Perry JRB, Styrkarsdottir U, Wilson SG, Piltonen T, Laisk T, Jarvelin MR, Burns K, Justice AE, Laivuori H, Ong KK, Goodarzi MO, Davis LK, Dunaif A, Lindgren CM, Laven JSE, Franks S, Visser JA, Welt CK, Karaderi T, Day FR. Nat Genet 2026

  PMID: 42026183

• Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations.

  Feitosa M, Schwander K, Miller C, Kraja A, Bentley A, Brown M, de Hesselle H, Noordam R, Lee S, Nagarajan P, Wang H, Giri A, Ammous F, Bartz T, Batini C, Brandenburg JT, Breyer M, Cordell H, Corley J, Dimotrov L, Do A, Du J, Giulianini F, Grace C, Gudmundsdottir V, Guo X, Harris S, Hasbani N, Herold J, Hikino K, Hofer E, Horimoto A, Hsu FC, Huang Z, Jackson A, Kang CH, Laguzzi F, Lakka T, Lefevre C, Luan J, Lyytikäinen LP, Meirhaeghe A, Muntaner M, Nakatochi M, Nardone GG, Nolte I, Nutile T, Palmer N, Patki A, Pecori A, Rao V, Richmond A, Richter M, Sanghvi M, Santin A, Stringham H, Takeuchi F, Tan YA, Tang J, Teder-Laving M, Trofimova O, Trompet S, van der Most P, Wang YX, Wang Z, Wang Y, Wang W, Ware E, Weiss S, Westerman K, Yu C, Zhu W, Ansari MAY, Anugu P, Argoty-Pantoja A, Attia J, Banas B, Bazzano L, Bis J, Boger C, Brody J, Broeckel U, Campbell H, Campbell A, Cennamo P, Checkley W, Chee ML, Chen G, Chen YD, Coley K, Collins S, Dallongeville J, de Silva HJ, Dupont C, Edwards T, Enzinger C, Faul J, Silva LF, Gepner A, Goel A, Gorski M, Graff M, Gu CC, He J, Heikkinen S, Hill-Burns E, Hung A, Hunt S, Irvin M, Kähönen M, Kardia S, Kho M, Koistinen H, Kolcic I, Komulainen P, Krieger JE, Launer L, Levy D, Liu J, McCormick J, McNeil J, Milaneschi Y, Miranda J, North K, Oravilahti A, Pattie A, Peyser P, Pianigiani G, Raffel L, Raitakari O, Ramsay M, Redkar S, Redmond P, Ridker P, Rosendaal F, Ruggiero D, Russ T, Sabanayagam C, Scartozzi A, Schmidt R, Scott L, Scott R, Shenkin S, Smit R, Smith JA, Da Soh Z, Spedicati B, Stott D, Sun Q, Sze G, Tai ES, Tesolin P, Triatin R, Vaitinadin NS, van Dam R, Vaucher J, Völker U, Völzke H, Wang C, Warren H, Wickremasinghe R, Willems van Dijk K, Xue C, Yamamoto K, Yao J, Yokota M, Zimmermann M, Amouyel P, Below J, Bergmann S, Bernabe-Ortiz A, Boehnke M, Boua P, Bowden D, Chasman D, Cheng CY, Ciullo M, Concas MP, Cox SR, Dauchet L, Deary I, Felix S, Fox E, Franceschini N, Freedman B, Gasparini P, Girotto G, Gudnason V, Hayward C, Heid I, Holliday E, Ichihara S, John C, Jonas J, Jukema JW, Kals M, Kato N, Keavney B, Kelly T, Laakso M, Lacaze P, Lange L, Leander K, Lee S, Lehtimäki T, Li C, Liu CT, Loos R, Penninx B, Pereira A, Polasek O, Psaty B, Rauramaa R, Rotimi C, Rotter J, Rudan I, Schmidt H, Sim X, Snieder H, Stark K, Terao C, Wagenknecht L, Wareham N, Watkins H, Weir D, Young K, Zhao W, Gauderman W, Morrison A, Fornage M, Chen H, O'Connell J, Manning A, de Vries P, de Las Fuentes L, Rao D, Munroe P, Province M, Winkler T. Res Sq 2026 Apr 03

  PMID: 41960332

• Thirty-Year Risk of Cardiovascular Disease Among Healthy Women According to Clinical Thresholds of Lipoprotein(a).

  Nordestgaard AT, Chasman DI, Moorthy V, Kraaijenhof JM, Cook NR, Lee IM, Buring JE, Ridker PM. JAMA Cardiol 2026 Feb 01

  PMID: 41499112