2023 PQG Conference: Diversity in Genetics and Genomics

Tuesday, October 17, 2023

8:30-9:00 am Registration & Breakfast | Joseph B. Martin Conference Center, 3rd Floor Rotunda

9:00-9:05 Opening Remarks

SESSION 1: Diversity for gene mapping and studying variant functions
Moderators: Yun Li and Kyle Vogan

* last 5 minutes of all session talks reserved for questions and discussion

9:05-9:55
Catherine Tcheandjieu Gueliatcha, | KEYNOTE SPEAKER
University of California, San Francisco
Why global genetic diversity matters in gene mapping and genetic discovery: Example of Coronary Artery Diseases 

9:55-10:25
Hailiang Huang| Massachusetts General Hospital, Harvard Medical School, Broad Institute
Leveraging genetic diversity to identify causal variants underlying human complex disorders

10:25-10:40
Zeyun Lu | Abstract Winner Platform Talk I
Multi-ancestry correlation-adjusted fine-mapping of molecular data identifies more cis-regulatory mechanisms

10:40-11:00  BREAK

11:00-11:30
Linda Kachuri | Stanford University
Ancestry-specific patterns of the genetic architecture of whole blood gene expression

11:30-12:00
Bogdan Pasaniuc |  University of California Los Angeles
Calibrated prediction intervals for polygenic scores across diverse contexts

12:00-1:15  LUNCH

SESSION 2: Diversity for translational genetics: polygenic risk and clinical implementation
Moderators: Jibril Hirbo and Nicholas Mancuso

1:15-2:05
Eimear Kenny | KEYNOTE SPEAKER
Icahn School of Medicine at Mt. Sinai
Race, identity, and genetic ancestry as variables in science and medicine

2:05-2:35
Jason Vassy | Harvard Medical School, l, Veterans Affairs (VA) Boston Healthcare System and Brigham and Women’s Hospital
Beyond the score: Promoting diversity in clinical PRS implementation

2:35-3:05
Paola Giusti-Rodriguez | University of Florida
Latin American Genomics Consortium: meaningful partnerships to advance psychiatric genomics studies in Latin America

3:05-3:30 BREAK

3:30-3:45
Haoyu Zhang | Abstract Winner Platform Talk II
Novel methods for multi-ancestry polygenic prediction and their evaluations in 5.1 million individuals of diverse ancestry

3:45-4:15
Tian Ge | Massachusetts General Hospital, Harvard Medical School
Improving the transferability and clinical utility of polygenic risk scores across global populations

4:15-6:00  Poster Session and Reception | 2nd floor lounge

Wednesday, October 18, 2023

8:30-9:00 am  Breakfast | Joseph B. Martin Conference Center, 3rd Floor Rotunda

SESSION 3: How do we move forward while acknowledging the past?
Moderators: Tamar Sofer and Linda Kachuri

9:00-9:50
Vence Bonham Jr | KEYNOTE SPEAKER
National Human Genome Research Institute
Enhancing Transparency in the Use of Population Descriptors in Genomics Research

9:50-10:20
Alicia Martin | Massachusetts General Hospital (MGH),  Harvard Medical School, Broad Institute
Genomics for the world: a comprehensive framework for genetic studies in diverse populations

10:25-10:40
Shoumita Dasgupta | Abstract Winner Platform Talk III
This is Our Lane: Scientific Advocacy and Allyship

10:40-11:00  BREAK

11:00 – 11:30
Daphne O. Martschenko | Stanford University
Genomics Beyond Medicine: Promise, Peril, and Social Responsibility

11:30 -12:15    PANEL DISCUSSION
Moderator:  Gen Wojcik
Panelists:
Vence Bonham Jr
Eimear Kenny
Alicia Martin
Daphne O. Martschenko
Catherine Tcheandjieu Gueliatcha

12:15-12:30  Closing Remarks and  Stellar Abstract Awards