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Nature Mental Health: Article Publication

Nature Mental Health: Article Publication

A new article published in Nature Mental Health used FEP-CAUSAL Collaboration data to examine comparative effectiveness of antipsychotic medications after first-episode psychosis.

The study used two target trials with different timeframes to examine relapse and hospitalization risk for patients who switched to long-acting injectable (LAI) medications versus those who remained on oral antipsychotics following first episode psychosis (FEP).

Researchers found little impact of long-acting injectable (LAI) therapies on hospitalization risk in the 18 months following first-episode psychosis. However, 3-year psychotic relapse risk indicated that long-acting injectable (LAI) medications may reduce relapse and have increased benefits in vulnerable patient subgroups.

CAUSALab researchers include Alejandro Szmulewicz, Gonzalo Martínez-Alés, Roger Logan, Miguel Hernán.

Read the Nature Mental Health article now.

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