Arpit Sharma

Biography

Publications

• The CRTC-1 transcriptional domain is required for COMPASS complex-mediated longevity in C. elegans.

  Silva-García CG, Láscarez-Lagunas LI, Papsdorf K, Heintz C, Prabhakar A, Morrow CS, Pajuelo Torres L, Sharma A, Liu J, Colaiácovo MP, Brunet A, Mair WB. Nat Aging 2023

• Neuronal mTORC1 inhibition promotes longevity without suppressing anabolic growth and reproduction in C. elegans.

  Smith HJ, Lanjuin A, Sharma A, Prabhakar A, Nowak E, Stine PG, Sehgal R, Stojanovski K, Towbin BD, Mair WB. PLoS Genet 2023

• Efficacy of longevity interventions in C. elegans is determined by early life activity of RNA splicing factors

  Sneha Dutta, Caroline Heintz, Maria C. Perez-Matos, Ayse Sena Mutlu, Mary E. Piper, Meeta Mistry, Arpit Sharma, Hannah J. Smith, Porsha Howell, Rohan Sehgal, Anne Lanjuin, Meng C. Wang, William B. Mair. 2025

• Neuronal mTORC1 inhibition promotes longevity without suppressing anabolic growth and reproduction in C. elegans

  Hannah J Smith, Anne Lanjuin, Arpit Sharma, Aditi Prabhakar, Emina Tabakovic, Rohan Sehgal, William B Mair. bioRxiv 2025

• Metabolic Communication and Healthy Aging: Where Should We Focus Our Energy?

  Smith HJ, Sharma A, Mair WB. Dev Cell 2020 07 20